Low level lead exposure and oxidative stress: Current opinions

2007 ◽  
Vol 383 (1-2) ◽  
pp. 57-64 ◽  
Author(s):  
M. Ahamed ◽  
M.K.J. Siddiqui
2014 ◽  
pp. 391-420
Author(s):  
Monica Bastos Paoliello ◽  
Ana Carolina de Almeida Lopes

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Michał Dobrakowski ◽  
Marta Boroń ◽  
Ewa Birkner ◽  
Aleksandra Kasperczyk ◽  
Ewa Chwalińska ◽  
...  

The present study was designed to explore the possible influence of subacute exposure to lead on the levels of selected essential metals, selected proteins related to them, and oxidative stress parameters in occupationally exposed workers. The study population included 36 males occupationally exposed to lead for 36 to 44 days. Their blood lead level at the beginning of the study was 10.7 ± 7.67 μg/dl and increased to the level of 49.1 ± 14.1 μg/dl at the end of the study. The levels of calcium, magnesium, and zinc increased significantly after lead exposure compared to baseline by 3%, 3%, and 8%, respectively, while the level of copper decreased significantly by 7%. The malondialdehyde (MDA) level and the activities of catalase (CAT) and superoxide dismutase (SOD) did not change due to lead exposure. However, the level of lipid hydroperoxides (LPH) in serum increased significantly by 46%, while the level of erythrocyte lipofuscin (LPS) decreased by 13%. The serum levels of essential metals are modified by a short-term exposure to lead in occupationally exposed workers. A short-term exposure to lead induces oxidative stress associated with elevated levels of LPH but not MDA.


2017 ◽  
Vol 24 (19) ◽  
pp. 16050-16061 ◽  
Author(s):  
Dharmendra K. Gupta ◽  
Frank Tawussi ◽  
Alex Hölzer ◽  
Linda Hamann ◽  
Clemens Walther

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0128567 ◽  
Author(s):  
Aline Barbosa Macedo ◽  
Luis Henrique Rapucci Moraes ◽  
Daniela Sayuri Mizobuti ◽  
Aline Reis Fogaça ◽  
Fernanda dos Santos Rapucci Moraes ◽  
...  

2019 ◽  
Vol 7 (3) ◽  
pp. 42
Author(s):  
Emmanuel Obeng-Gyasi

Lead exposure among pregnant U.S. women was examined via the National Health and Nutrition Examination Survey (NHANES) 2009–2016 data to examine its role in bad cholesterol and oxidative stress. Mean values of the clinical markers non-high density lipoprotein cholesterol (non-HDL-c) and gamma-glutamyl transferase (GGT), a marker of oxidative stress, were explored. In four quartiles of lead exposure, clinical makers were compared. Binary logistic regression predicted the likelihood of elevated clinical markers in pregnant compared to non-pregnant women, while linear regression was used to examine associations between blood lead levels (BLL) and the clinical markers of interest. Mean non-HDL-c was statistically significantly more elevated in pregnant women than non-pregnant women. Mean GGT levels were more statistically significantly elevated in the highest quartile of BLL exposure among pregnant women than in the lower quartiles. In binary logistic regression models, pregnant women were statistically significantly more likely to have elevated non-HDL-c, while in linear regression BLL was statistically significantly associated with GGT levels in pregnant women. Lead exposure in pregnant women is an issue of public health concern that must continue to be studied.


2017 ◽  
Vol 190 ◽  
pp. 52-59 ◽  
Author(s):  
Eveline Geiser ◽  
Chrysa Retsa ◽  
Jean-François Knebel ◽  
Carina Ferrari ◽  
Raoul Jenni ◽  
...  

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