The effects of Roundup® in embryo development and energy metabolism of the zebrafish (Danio rerio)

2019 ◽  
Vol 222 ◽  
pp. 74-81 ◽  
Author(s):  
Ottassano S. Panetto ◽  
Helga F. Gomes ◽  
Danielle S. Fraga Gomes ◽  
Eldo Campos ◽  
Nelilma C. Romeiro ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Embryo Development ◽  
Danio Rerio

HIF-1 regulates energy metabolism of Tibetan chicken brain during embryo development under hypoxia

2021 ◽  
Author(s):  
Qiguo Tang ◽  
Qinqin Xu ◽  
Cui Ding ◽  
Hao Zhang ◽  
Yao Ling ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Embryo Development ◽  
Target Genes ◽  
Tca Cycle ◽  
Tibet Plateau ◽  
Chicken Breed ◽  
Indigenous Breed ◽  
Hypoxic Environment ◽  
Tibetan Chicken ◽  
Qinghai Tibet Plateau

The Tibetan chickens (Gallus gallus; TBC) are an indigenous breed distributed in Qinghai-Tibet Plateau that are well adapted to a hypoxic environment. The energy metabolism of embryo brains in TBCs under hypoxia has been little reported. This study investigated changes in energy metabolism of TBCs brain during embryo development under hypoxia. We found TBCs exhibited a change of glycolysis and TCA cycle during embryo development under hypoxia. HIF-1 potentially involved this by directly inducing the overexpression of PDK1 and glycolytic genes, hexokinase(HK1) and lactate dehydrogenase A (LDHA) to increase glycolysis of TBCs to adapt hypoxia. Although these may not be unique to TBCs, as we had also found similar results in Dwarf Laying Chickens (DLCs), a lowland chicken breed, TBCs had stronger regulating ability. In summary, our study revealed HIF-1 induced energy metabolism change in TBCs brain via upregulating expressions of PDK1 and other HIF-1 target genes like HK1, LDHA to increase glycolysis for TBCs hypoxia adaptation during embryo development. It indicates the potential application of TBCs energy metabolism research for other animals living on the Qinghai-Tibet Plateau.

Monobutyl phthalate (MBP) induces energy metabolism disturbances in the gills of adult zebrafish (Danio rerio)

2020 ◽  
Vol 266 ◽  
pp. 115288
Author(s):  
Yue Tao ◽  
Yang Yang ◽  
Yaqi Jiao ◽  
Song Wu ◽  
Guangxue Zhu ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Danio Rerio ◽  
Adult Zebrafish ◽  
Monobutyl Phthalate

Acute exposure to bis(2-ethylhexyl)phthalate disrupts calcium homeostasis, energy metabolism and induces oxidative stress in the testis of Danio rerio

Biochimie ◽  
2020 ◽  
Vol 175 ◽  
pp. 23-33 ◽  
Author(s):  
Hemily Batista-Silva ◽  
Betina Fernanda Dambrós ◽  
Keyla Rodrigues ◽  
Patrícia Acordi Cesconetto ◽  
Ariane Zamoner ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Energy Metabolism ◽  
Calcium Homeostasis ◽  
Danio Rerio ◽  
Acute Exposure ◽  
Ethylhexyl Phthalate

scholarly journals Dichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio

BMC Genomics ◽  
2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Tri M. Bui-Nguyen ◽  
Christine E. Baer ◽  
John A. Lewis ◽  
Dongren Yang ◽  
Pamela J. Lein ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Danio Rerio ◽  
Large Scale

Phenanthrene exposure produces cardiac defects during embryo development of zebrafish (Danio rerio) through activation of MMP-9

Chemosphere ◽  
2013 ◽  
Vol 93 (6) ◽  
pp. 1168-1175 ◽  
Author(s):  
Youyu Zhang ◽  
Lixing Huang ◽  
Chonggang Wang ◽  
Dongxu Gao ◽  
Zhenghong Zuo
Keyword(s):  
Embryo Development ◽  
Danio Rerio ◽  
Cardiac Defects
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