Cloning, characterization and tissue distribution of a pi-class glutathione S-transferase from clam (Venerupis philippinarum): Response to benzo[α]pyrene exposure

2010 ◽  
Vol 152 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Chaoqun Xu ◽  
Luqing Pan ◽  
Na Liu ◽  
Lin Wang ◽  
Jingjing Miao
Keyword(s):  
Tissue Distribution ◽  
Glutathione S Transferase ◽  
Venerupis Philippinarum

Molecular cloning and tissue distribution of a 26-kilodalton Schistosoma mansoni glutathione S-transferase

1990 ◽  
Vol 41 (1) ◽  
pp. 35-44 ◽  
Author(s):  
François Trottein ◽  
Marie Paule Kieny ◽  
Claudie Verwaerde ◽  
Gérard Torpier ◽  
Raymond J. Pierce ◽  
...  
Keyword(s):  
Schistosoma Mansoni ◽  
Tissue Distribution ◽  
Molecular Cloning ◽  
Glutathione S Transferase

Expression and tissue distribution of plaice glutathione S-transferase A

1992 ◽  
Vol 34 (1-4) ◽  
pp. 237-241 ◽  
Author(s):  
Michael J. Leaver ◽  
Karen Scott ◽  
Stephen G. George
Keyword(s):  
Tissue Distribution ◽  
Glutathione S Transferase

scholarly journals Tissue distribution and subunit structures of the multiple forms of glutathione S-transferase in the rat

1981 ◽  
Vol 193 (1) ◽  
pp. 367-370 ◽  
Author(s):  
N C Scully ◽  
T J Mantle
Keyword(s):  
Tissue Distribution ◽  
Rat Kidney ◽  
Multiple Forms ◽  
Glutathione S Transferase

A study of the subunit structures of the multiple forms of glutathione S-transferase in rat kidney, testis, lung and spleen is shown to be consistent with a proteolytic model for the generation of the multiple forms.

scholarly journals Secretion of glutathione S-transferase isoforms in the seminiferous tubular fluid, tissue distribution and sex steroid binding by rat GSTM1

1999 ◽  
Vol 340 (1) ◽  
pp. 309 ◽  
Author(s):  
Sikha Bettina MUKHERJEE ◽  
S. ARAVINDA ◽  
B. GOPALAKRISHNAN ◽  
Sushma NAGPAL ◽  
Dinakar M. SALUNKE ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Sex Steroid ◽  
Glutathione S Transferase ◽  
Steroid Binding

Tissue Distribution and Properties of Glutathione S-transferases in Micromelalopha troglodyta (Lepidoptera: Notodontidae)

2008 ◽  
Vol 43 (3) ◽  
pp. 268-278 ◽  
Author(s):  
Fang Tang ◽  
Xiu-Bo Zhang ◽  
Yu-Sheng Liu ◽  
Xi-Wu Gao
Keyword(s):  
Tissue Distribution ◽  
Tannic Acid ◽  
Fat Body ◽  
Inhibitory Effect ◽  
Transferase Activity ◽  
Glutathione S Transferase ◽  
Important Pest ◽  
Glutathione S Transferases ◽  
Gst Activity ◽  
Different Tissues

The small prominent, Micromelalopha troglodyta (Graeser) (Lepidoptera: Notodontidae), is an important pest of poplar in China. Glutathione S-transferases are known to be responsible for adaptation mechanisms of M. troglodyta. Thus, the tissue distribution and kinetic constants of glutathione S-transferase activity in the small prominent were studied. Significant differences in glutathione S-transferase (GST) activity and distribution percentages of GST activity and kinetic characteristics were observed among 4 tissues (head, midgut, fat body and integument). Furthermore, the inhibition of glutathione S-transferase activity in 4 tissues by 21 inhibitors was conducted. The results showed the inhibition of GST activity of different tissues by 21 inhibitors is different. For GST activity in heads, chlorpyrifos, profenofos, lambda-cyhalothrin, fipronil and quercetin were the best inhibitors tested. Tannic acid was the most potent inhibitor of midgut GST activity. In the fat body, GST activity was inhibited most by tannic acid, chlorpyrifos and profenofos. The inhibitory effect of profenofos and phoxim was highest for GST activity in the integument. Our results showed that glutathione S-transferases in different tissues are qualitatively different in isozyme composition and thus different in sensitivity to inhibitors.

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