Cloning and expression characterization of peroxisome proliferator-activated receptors (PPARs) with their agonists, dietary lipids, and ambient salinity in rabbitfish Siganus canaliculatus

Author(s):  
Cuihong You ◽  
Danli Jiang ◽  
Qinghao Zhang ◽  
Dizhi Xie ◽  
Shuqi Wang ◽  
...  
2009 ◽  
Vol 33 (5) ◽  
pp. 844-850 ◽  
Author(s):  
Fei-Fei YU ◽  
Jian-Fang GUI ◽  
Li ZHOU ◽  
Mei-Fang WANG ◽  
Xiang-Yong YU

Lipids ◽  
2016 ◽  
Vol 51 (9) ◽  
pp. 1051-1063 ◽  
Author(s):  
Qinghao Zhang ◽  
Cuihong You ◽  
Fang Liu ◽  
Wendi Zhu ◽  
Shuqi Wang ◽  
...  

PPAR Research ◽  
2007 ◽  
Vol 2007 ◽  
pp. 1-6 ◽  
Author(s):  
Céline Gaudel ◽  
Paul A. Grimaldi

Peroxisome proliferator-activated receptors (PPARs) are transcription factors that act as lipid sensors and adapt the metabolic rates of various tissues to the concentration of dietary lipids. PPARs are pharmacological targets for the treatment of metabolic disorders. PPARαand PPARγare activated by hypolipidemic and insulin-sensitizer compounds, such as fibrates and thiazolidinediones. The roles of PPARβ/δin metabolic regulations remained unclear until recently. Treatment of obese monkeys and rodents by specific PPARβ/δagonists promoted normalization of metabolic parameters and reduction of adiposity. Recent evidences strongly suggested that some of these beneficial actions are related to activation of fatty acid catabolism in skeletal muscle and also that PPARβ/δis involved in the adaptive responses of skeletal muscle to environmental changes, such as long-term fasting or physical exercise, by controlling the number of oxidative myofibers. These observations indicated that PPARβ/δagonists might have therapeutic usefulness in metabolic syndrome by increasing fatty acid consumption in skeletal muscle and reducing obesity.


Lipids ◽  
2004 ◽  
Vol 39 (11) ◽  
pp. 1085-1092 ◽  
Author(s):  
Evridiki Boukouvala ◽  
Efthimia Antonopoulou ◽  
Laurence Favre-Krey ◽  
Amalia Diez ◽  
José M. Bautista ◽  
...  

2002 ◽  
Vol 45 (6) ◽  
pp. 655-662 ◽  
Author(s):  
Xiaodong Sun ◽  
Yehua Ge ◽  
Jing Ma ◽  
Zuoren Yu ◽  
Sai Li ◽  
...  

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