Amino acid derived amides and hydroxamic acids as ligands for asymmetric transfer hydrogenation in aqueous media

2011 ◽  
Vol 12 (12) ◽  
pp. 1118-1121 ◽  
Author(s):  
Katrin Ahlford ◽  
Hans Adolfsson
Keyword(s):  
Amino Acid ◽  
Aqueous Media ◽  
Hydroxamic Acids ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation

scholarly journals Design of Iridium N-Heterocyclic Carbene Amino Acid Catalysts for Asymmetric Transfer Hydrogenation of Aryl Ketones

Catalysts ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 671
Author(s):  
Chad M. Bernier ◽  
Joseph S. Merola
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Enantiomeric Excess ◽  
Transfer Hydrogenation ◽  
Acid Catalysts ◽  
Asymmetric Transfer Hydrogenation ◽  
Reaction Conditions ◽  
Chiral Complexes ◽  
Acetophenone Derivatives ◽  
Aryl Ketones

A series of chiral complexes of the form Ir(NHC)2(aa)(H)(X) (NHC = N-heterocyclic carbene, aa = chelated amino acid, X = halide) was synthesized by oxidative addition of -amino acids to iridium(I) bis-NHC compounds and screened for asymmetric transfer hydrogenation of ketones. Following optimization of the reaction conditions, NHC, and amino acid ligands, high enantioselectivity was achieved when employing the Ir(IMe)2(l-Pro)(H)(I) catalyst (IMe = 1,3-dimethylimidazol-2-ylidene), which asymmetrically reduces a range of acetophenone derivatives in up to 95% enantiomeric excess.

Third-Generation Amino Acid Furanoside-Based Ligands from d -Mannose for the Asymmetric Transfer Hydrogenation of Ketones: Catalysts with an Exceptionally Wide Substrate Scope

2016 ◽  
Vol 358 (24) ◽  
pp. 4006-4018 ◽  
Author(s):  
Jèssica Margalef ◽  
Tove Slagbrand ◽  
Fredrik Tinnis ◽  
Hans Adolfsson ◽  
Montserrat Diéguez ◽  
...  
Keyword(s):  
Amino Acid ◽  
Transfer Hydrogenation ◽  
Third Generation ◽  
Asymmetric Transfer Hydrogenation

Asymmetric transfer hydrogenation of prochiral ketones in aqueous media with chiral water-soluble and heterogenized bifunctional catalysts of the RhCp*-type ligand

Chirality ◽  
2010 ◽  
Vol 23 (2) ◽  
pp. 178-184 ◽  
Author(s):  
Angélica Barrón-Jaime ◽  
Oscar F. Narvaez-Garayzar ◽  
Jorge González ◽  
Valentín Ibarra-Galván ◽  
Gerardo Aguirre ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Water Soluble ◽  
Transfer Hydrogenation ◽  
Bifunctional Catalysts ◽  
Asymmetric Transfer Hydrogenation ◽  
Prochiral Ketones

Surfactant-accelerated asymmetric transfer hydrogenation with recyclable water-soluble catalyst in aqueous media

RSC Advances ◽  
2013 ◽  
Vol 3 (6) ◽  
pp. 1825-1834 ◽  
Author(s):  
Jiahong Li ◽  
Xuefeng Li ◽  
Yaping Ma ◽  
Jiashou Wu ◽  
Fei Wang ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Water Soluble ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation
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