Effect of Brain Natriuretic Peptide and Body Mass Index on Plasma Adiponectin Level

2006 ◽  
Vol 12 (8) ◽  
pp. S170
Author(s):  
Tanaka Toshinari ◽  
Takayoshi Tsutamoto ◽  
Hiroshi Sakai ◽  
Masanori Fujii ◽  
Takashi Yamamoto ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Body Mass ◽  
Adiponectin Level ◽  
Plasma Adiponectin ◽  
Plasma Adiponectin Level

THU0140 Plasma Adiponectin Level and Body Mass Index (BMI) Predict Response to Treatment in Patients with Rheumatoid Arthritis

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A210.2-A210 ◽  
Author(s):  
D. X. Xibille ◽  
S. E. Hernández Góngora ◽  
C. Bustos Bahena ◽  
E. Ortíz Panozo ◽  
J. L. Montiel Hernandez
Keyword(s):  
Rheumatoid Arthritis ◽  
Body Mass Index ◽  
Body Mass ◽  
Adiponectin Level ◽  
Response To Treatment ◽  
Plasma Adiponectin ◽  
Plasma Adiponectin Level

In hemodialysis, adiponectin, and pro-brain natriuretic peptide levels may be subjected to variations in body mass index

2011 ◽  
Vol 15 (4) ◽  
pp. 477-484 ◽  
Author(s):  
Hernan TRIMARCHI ◽  
Alexis MURYAN ◽  
Mariana DICUGNO ◽  
Mariano FORRESTER ◽  
Fernando LOMBI ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Body Mass

Inverse Correlation of Venous Brain Natriuretic Peptide Levels with Body Mass Index Is due to Decreased Production

Cardiology ◽  
2017 ◽  
Vol 137 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Zubair Shah ◽  
Mark Wiley ◽  
Arun Mahankali Sridhar ◽  
Reza Masoomi ◽  
Mazda Biria ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Body Mass ◽  
Inverse Relationship ◽  
Univariate Analysis ◽  
Cardiac Resynchronization ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Objective: The aim of this paper was to study the association between body mass index (BMI) and coronary sinus (CS) brain natriuretic peptide (BNP) levels in patients with heart failure and reduced systolic function (HFrEF). Background: There is an inverse relationship between systemic venous BNP (V-BNP) levels and BMI in patients with HFrEF. It is unclear whether this finding is due to decreased production or due to an increased metabolism of BNP. Since CS-BNP levels reflect BNP production, we hypothesized that assessing the correlation of CS-BNP levels with BMI would provide insight into the mechanism of this inverse relationship of V-BNP and BMI. Methods: We prospectively enrolled 54 subjects with HFrEF who were to undergo cardiac resynchronization device implantation. CS-BNP, V-BNP, and arterial BNP (A-BNP) levels were measured during the implant procedure. Subjects were divided into 2 groups based on their BMI (group 1: BMI <30 and group 2: BMI ≥30). Results: The mean age of the overall study group was 64 ± 10 years. Average BMI for group 1 was 25.8 ± 2.8 and 36.8 ± 4.6 for group 2 (p < 0.03). A history of hypertension was present in 55% (n = 26) of the subjects, while diabetes was reported in 31% (n = 15). Serum creatinine was 1.0 ± 0.2 mg/dL and TSH 2.1 ± 1.4 mIU/L. 79% of the subjects were receiving β-blockers, while 94% were receiving angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. The mean CS-BNP, V-BNP, and A-BNP levels in group 2 were significantly lower than in group 1 (286.2 ± 170.5 vs. 417.5 ± 247.5 pg/mL, p = 0.04; 126.6 ± 32.5 vs. 228 ± 96.4 pg/mL, p = 0.01; and 151.9 ± 28.6 vs. 242 ± 88.8 pg/mL, p = 0.04, respectively). Univariate analysis and multivariate regression adjusted for age, diabetes mellitus, sex, glomerular filtration rate, and left atrial size confirmed BMI as an independent predictor of CS-BNP levels (β = -0.372, p = 0. 03) in our study. Conclusions: In this study, we demonstrate an inverse relationship between CS-BNP levels and BMI in patients with HFrEF. These findings suggest that the previously established inverse relationship between V-BNP and BMI is due to a decreased cardiac production of BNP in obese patients rather than from increased peripheral metabolism.

Gender Dimorphic Associations between N-Terminal Pro-Brain Natriuretic Peptide, Body Mass Index and Blood Pressure in Children and Adolescents

2010 ◽  
Vol 73 (5) ◽  
pp. 341-348 ◽  
Author(s):  
Panagiota Pervanidou ◽  
Athanassios Akalestos ◽  
Sophia Sakka ◽  
Christina Kanaka-Gantenbein ◽  
Ioannis Papassotiriou ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Brain Natriuretic Peptide ◽  
Children And Adolescents ◽  
Natriuretic Peptide ◽  
Body Mass
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