Anemic Patients with Heart Failure and a Normal Ejection Fraction Have a Reduced Red Cell Volume, True Anemia, and Concomitant Plasma Volume Expansion

2006 ◽  
Vol 12 (6) ◽  
pp. S9
Author(s):  
Rose S. Cohen ◽  
Raja J. Wajahat ◽  
Inna Titova ◽  
Ellie J. Coromilas ◽  
Mathew S. Maurer
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Cell Volume ◽  
Plasma Volume ◽  
Volume Expansion ◽  
Normal Ejection Fraction ◽  
Red Cell ◽  
Plasma Volume Expansion ◽  
Red Cell Volume ◽  
Patients With Heart Failure

scholarly journals TOTAL RED CELL VOLUME, PLASMA VOLUME, AND SODIUM SPACE IN CONGESTIVE HEART FAILURE 1

1951 ◽  
Vol 30 (12 Pt 2) ◽  
pp. 1471-1482 ◽  
Author(s):  
Theodore C. Prentice ◽  
Nathaniel I. Berlin ◽  
Grace M. Hyde ◽  
Robert J. Parsons ◽  
John H. Lawrence ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Cell Volume ◽  
Plasma Volume ◽  
Red Cell ◽  
Red Cell Volume

scholarly journals Chronic heart failure leads to an expanded plasma volume and pseudoanaemia, but does not lead to a reduction in the body's red cell volume

2008 ◽  
Vol 29 (19) ◽  
pp. 2343-2350 ◽  
Author(s):  
C. Adlbrecht ◽  
S. Kommata ◽  
M. Hulsmann ◽  
T. Szekeres ◽  
C. Bieglmayer ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Cell Volume ◽  
Plasma Volume ◽  
Red Cell ◽  
Red Cell Volume

Physiological and hematologic responses to summer and winter dry-heat acclimation

1981 ◽  
Vol 50 (4) ◽  
pp. 792-798 ◽  
Author(s):  
Y. Shapiro ◽  
R. W. Hubbard ◽  
C. M. Kimbrough ◽  
K. B. Pandolf
Keyword(s):  
Cell Volume ◽  
Plasma Volume ◽  
Volume Expansion ◽  
Sweat Rate ◽  
Heat Acclimation ◽  
Red Cell ◽  
Plasma Volume Expansion ◽  
Set Point ◽  
Dry Heat ◽  
C 30

Differences between acclimation to heat at the end of winter (W) and at the end of summer (S) were studied on the same eight male volunteers. Subjects were exposed to 40 degrees C, 30% rh for 10 consecutive days on two separate occasions approximately 5 mo apart (S and W). Daily exposures lasted 120 min: 10 min rest, 50 min walking 1.34 m . s-1 on the level, 10 min rest, 50 min walking. During W acclimation, rectal temperature (Tre) and heart rate (HR) decreased, sweat rate (msw) remained unchanged, and plasma and red cell volume of the blood expanded. During S acclimation, HR decreased while Tre and msw remained unchanged, and plasma volume increased. The Tre of the acclimated subjects remained higher in W, and the msw lower, than in S. It was concluded that acclimation does not totally eliminate the seasonal differences in thermoregulatory set point and sweating sensitivity. Further, acclimation to a more severe heat did not lower the thermoregulatory set point that was achieved by natural acclimatization to a milder heat but affected the cardiovascular adjustment and caused greater plasma volume expansion. W acclimation caused both plasma and blood cell volume expansion, whereas S acclimation affected only plasma volume.

scholarly journals Time course of red cell volume and plasma volume over six months in compensated chronic heart failure

2021 ◽  
Author(s):  
Christoph Ahlgrim ◽  
Florian Seiler ◽  
Philipp Birkner ◽  
Dawid Leander Staudacher ◽  
Sebastian Grundmann ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Cell Volume ◽  
Plasma Volume ◽  
Time Course ◽  
Red Cell ◽  
Red Cell Volume

Blood Volume Measurement in Baboons: Simultaneous Estimation of Red Cell Volume and Plasma Volume

1985 ◽  
Vol 14 (6) ◽  
pp. 345-356
Author(s):  
Michael G. Garner ◽  
Andrew F. Phippard ◽  
John S. Horvath ◽  
Geoffrey G. Duggin ◽  
David J. Tiller
Keyword(s):  
Cell Volume ◽  
Blood Volume ◽  
Plasma Volume ◽  
Volume Measurement ◽  
Simultaneous Estimation ◽  
Red Cell ◽  
Red Cell Volume ◽  
Blood Volume Measurement

Plasma volume during stress in man: osmolality and red cell volume

1979 ◽  
Vol 47 (5) ◽  
pp. 1031-1038 ◽  
Author(s):  
J. E. Greenleaf ◽  
V. A. Convertino ◽  
G. R. Mangseth
Keyword(s):  
Cell Volume ◽  
Plasma Volume ◽  
Heat Exposure ◽  
Plasma Osmolality ◽  
Red Cell ◽  
Short Term ◽  
Red Cell Volume ◽  
Altitude Exposure ◽  
Periods Of Stress

Our purpose was 1) to test the hypothesis that in man there is a range of plasma osmolality within which the red cell volume (RCV) and mean corpuscular volume (MCV) remain essentially constant and 2) to determine the upper limit of this range. During a variety of stresses--submaximal and maximal exercise, heat and altitude exposure, +Gz acceleration, and tilting--changes in plasma osmolality between -1 and +13 mosmol/kg resulted in essentially no change in the regression of percent change in plasma volume (PV) calculated from a change in hematocrit (Hct) on that calculated from a change in Hct + hemoglobin (Hb), i.e., the RCV and MCV were constant. Factors that do not influence RCV are the level of metabolism, heat exposure at rest, and short-term orthostasis (heat-to-foot acceleration). Factors that may influence RCV are exposure to high altitude and long-term orthostasis (head-up tilting). Factors that definitely influence RCV are prior dehydration and extended (greater than 2 h) periods of stress. Thus, either the Hct or the Hct + Hb equations can be used to calculate percent changes in PV under short-term (less than 2 h) periods of stress when the change in plasma osmolality is less than 13 mosmol/kg.

Circulating and tissue hematocrits of normal unanesthetized mice

1959 ◽  
Vol 196 (2) ◽  
pp. 420-422 ◽  
Author(s):  
Julius J. Friedman
Keyword(s):  
Serum Albumin ◽  
Cell Volume ◽  
Plasma Volume ◽  
Venous Blood ◽  
Red Cells ◽  
Red Cell ◽  
Volume Data ◽  
Red Cell Volume ◽  
Volume Measurements ◽  
Total Body

The circulating and tissue hematocrits of normal unanesthetized mice were determined by means of independent red cell and plasma volume measurements. The red cell volume-indicator which was used in this study was radioiron (Fe59) tagged red cells. The plasma volume data were derived by means of radioiodine (I131) labeled serum albumin and were reported earlier (Friedman, Proc. Soc. Exper. Biol. & Med. 88: 323, 1955). The hematocrits of the various tissues were found to be: for spleen 51.3, lung 47.9, muscle 49.9, liver 38.9, intestine, 32.2, skin 29.2 and kidney 24.0%. The total body hematocrit was 35.4% as compared to 48.4 for venous blood. All tissues, with the exception of spleen and lung, contained hematocrits which were lower than that of venous blood suggesting the presence of some mechanism within the various tissues which is capable of effectively separating plasma from red cells.

Adjustments of the Circulatory System in Normal Dogs to Massive Transfusions

1956 ◽  
Vol 186 (1) ◽  
pp. 92-96 ◽  
Author(s):  
R. A. Huggins ◽  
E. L. Smith ◽  
R. A. Seibert
Keyword(s):  
Cell Volume ◽  
Plasma Volume ◽  
Vascular System ◽  
Circulatory System ◽  
Red Cell ◽  
Group V ◽  
Red Cell Volume ◽  
Group Iii ◽  
Group I ◽  
Transfusion Volume

On the basis of the amount of blood transfused in cubic centimeters per kilogram the dogs were arranged into five groups: group I, 0.0–49.0 cc/kg, group II, 50.0–99.0 cc/kg, group III, 100.0–149.0 cc/kg, group IV, 150.0– 199.0 cc/kg and group V, 200.0–249.0 cc/kg. The determinations made in each group were plasma volume, plasma proteins, hematocrit and hemoglobin. Plasma including protein escaped rapidly from the vascular system even with the smallest transfusion and in the last two groups the plasma lost exceeded that infused. Thus, any method of determining blood volume based on measurement of plasma volume must be in error. The loss of plasma protein became progressively greater as the amount of transfusion increased. The apparent increase in measured red cell volume over the expected in groups I, II and III was probably the result of loss of dye from the circulation, giving an overestimate of plasma and red cell volume. There was no evidence that cells leave the circulation until the transfusion volume became very large ( groups IV, V) and hemorrhage supervened.

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