Computer-aided quantification of contrast agent spatial distribution within atherosclerotic plaque in contrast-enhanced ultrasound image sequences

2014 ◽  
Vol 13 ◽  
pp. 50-61 ◽  
Author(s):  
Qi Zhang ◽  
Chaolun Li ◽  
Hong Han ◽  
Lijing Yang ◽  
Yuanyuan Wang ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Contrast Agent ◽  
Atherosclerotic Plaque ◽  
Ultrasound Image ◽  
Image Sequences ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Computer Aided

Nonrigid motion compensation in B-mode and contrast enhanced ultrasound image sequences of the carotid artery

2014 ◽  
Author(s):  
Diego D. B. Carvalho ◽  
Zeynettin Akkus ◽  
Johan G. Bosch ◽  
Stijn C. H. van den Oord ◽  
Wiro J. Niessen ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Motion Compensation ◽  
Ultrasound Image ◽  
Image Sequences ◽  
Nonrigid Motion ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

scholarly journals Comparison of transducers with different frequencies in breast contrast-enhanced ultrasound (CEUS) using SonoVue as contrast agent

2016 ◽  
Vol 89 (1063) ◽  
pp. 20151050 ◽  
Author(s):  
Yong-Mei Wang ◽  
Wei Fan ◽  
Kai Zhang ◽  
Li Zhang ◽  
Zhen Tan ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Contrast-enhanced ultrasound (CEUS) in assessing early response among patients with invasive breast cancer undergoing neoadjuvant chemotherapy

2016 ◽  
Vol 58 (4) ◽  
pp. 394-402 ◽  
Author(s):  
Ariel Saracco ◽  
Botond K Szabó ◽  
Ervin Tánczos ◽  
Jonas Bergh ◽  
Thomas Hatschek
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Contrast Agent ◽  
Real Time ◽  
Invasive Breast Cancer ◽  
Early Response ◽  
Contrast Enhanced Ultrasound ◽  
Time Harmonic ◽  
Contrast Enhanced ◽  
Significant Difference

Background One of the big challenges in onco-radiology is to find a reliable imaging method that may predict early response during the first cycles of any neoadjuvant chemotherapy. Purpose To evaluate the use of real-time harmonic contrast-enhanced ultrasound (CEUS) in predicting early response in breast cancer tumors under neoadjuvant chemotherapy (NAC) treatment. Material and Methods Nineteen consecutive patients with invasive breast cancer were evaluated with a bolus dose of 2.4 mL contrast agent using CEUS, before and after two cycles of epirubicin and docetaxel. The lognormal function was used for quantitative analysis of kinetic data to evaluate early response. Results There was statistically significant difference in time-to-peak ( tp) between responders and non-responders (two sample t-test, P = 0.027) where tp was significantly longer at the week 5 than at the baseline scan among responders when compared to non-responders. Conclusion In-flow of intravascular contrast agent in tumors is significantly slower in responders at real-time harmonic CEUS, and might be effectively used for the evaluation of early response to chemotherapy in invasive breast cancer. However, further investigations in a larger and more heterogeneous population should be performed to corroborate the reliability of the method.

scholarly journals K-Means Clustering Algorithm-Based Detection of Carotid Atherosclerotic Plaque Using Contrast-Enhanced Ultrasound Images

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Ruitao Zhou ◽  
Ruijie Zhou ◽  
Zhibo Zhu
Keyword(s):  
Atherosclerotic Plaque ◽  
Clustering Algorithm ◽  
Detection Method ◽  
Control Group ◽  
Carotid Atherosclerotic Plaque ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Group A ◽  
Group B ◽  
Sensitivity Specificity

The aim of this study was to investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) based on the K-means clustering (KMC) algorithm for the vulnerability of carotid atherosclerotic plaque (CAA). In this study, 90 patients with CAA were enrolled into a control group (group A) and an experimental group (group B). The angiography method and KMC-based ultrasound detection were applied to diagnose the CAA patients from the two groups, respectively. The results showed that the sensitivity, specificity, and positive predictive value of patients from group B (92.3%, 90.1%, and 94.8%) for diagnosing CAA were obviously higher than those of patients from group A (81.4%, 88.6%, and 75.3%) ( P < 0.05 ). The detection rate of patients from group B (83%, 85%) was dramatically higher than that of patients from group A (65%, 71%) in terms of artery bifurcation and CAA ( P < 0.05 ). Besides, patients from group B were more satisfied with their diagnostic method than group A ( P < 0.05 ). In conclusion, the ultrasound detection method based on KMC had high sensitivity, specificity, and accuracy in the detection of CAA. In addition, ultrasound detection was better than angiography in the diagnosis of plaque in different parts, and it was worthwhile to apply the ultrasound detection method based on KMC in clinical practice.

scholarly journals Contrast Enhanced Ultrasound in the Diagnosis and Evaluation of the Efficiency of Chemotherapy in Patients with Colorectal Liver Metastases

2021 ◽  
Vol 101 (6) ◽  
pp. 324-332
Author(s):  
E. V. Kovaleva ◽  
G. T. Sinyukova ◽  
T. Yu. Danzanova ◽  
P. I. Lepedatu ◽  
E. A. Gudilina ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Arterial Phase ◽  
Contrast Enhanced Ultrasound ◽  
Time Curve ◽  
Entire Volume ◽  
Contrast Enhanced ◽  
Group 2 ◽  
Group 1

Objective: to determine the possibilities of contrast-enhanced ultrasound (CEUS) in identifying and evaluating the efficiency of chemotherapy in patients with colorectal liver metastases (CLM).Material and methods. The investigation enrolled 28 patients with CLM. The patients were divided into two groups: Group 1 – 15 pretreatment patients; Group 2 – 13 posttreatment patients with process stabilization. All the patients underwent standard B-mode ultrasound of the liver and that using the contrast agent SonoVue ® (Bracco, Italy), by recording and estimating the parameters of the intensity-time curve (CIV). Liver CEUS assesses the nature of contrasting metastases in three phases (arterial, venous, and delay ones).Results. The investigators identified three types of contrast agent accumulation in CLM in the arterial phase: along the periphery of the lesions (in 60% of the patients of Group 1, in 76.9% in Group 2), homogeneously over the entire volume (in 26.7% in Group 1 and in 0.08% in Group 2), in parallel with intact liver parenchyma (13.3% in Group 1 and 23.02% in Group 2). In the delay phase, more metastases were detected in 4 cases (14.3%). Estimation of CIV parameters showed a difference at the beginning of contrast enhancement stages between the patients in both groups. Group 1 exhibited the early contrasting of liver metastases (19.3 sec); Group 2 displayed the late washout of a contrast agent (65.9 sec).Conclusion. CEUS versus B-mode ultrasound improves the imaging of liver metastases. The change in the vascular architectonics and hemodynamics in CLM after chemotherapy is reflected in the alteration of the rate of contrast accumulation and washout from the metastases, which allows CEUS to be used in the evaluation of the efficiency of this treatment.

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