Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum Reproducibly Improves Symptoms of Body Dysmorphic Disorder

2016 ◽  
Vol 9 (6) ◽  
pp. 957-959 ◽  
Author(s):  
Juan Carlos Baldermann ◽  
Sina Kohl ◽  
Veerle Visser-Vandewalle ◽  
Martin Klehr ◽  
Daniel Huys ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Body Dysmorphic Disorder ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression

2009 ◽  
Vol 65 (4) ◽  
pp. 267-275 ◽  
Author(s):  
Donald A. Malone ◽  
Darin D. Dougherty ◽  
Ali R. Rezai ◽  
Linda L. Carpenter ◽  
Gerhard M. Friehs ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Resistant Depression ◽  
Deep Brain ◽  
Stimulation Of

S.07.05 Deep brain stimulation of the ventral striatum affects consummatory and motivated behaviour in a location-specific manner

2011 ◽  
Vol 21 ◽  
pp. S196-S197
Author(s):  
G. van der Plasse ◽  
R. Schrama ◽  
S. van Seters ◽  
H.G.M. Westenberg ◽  
L.J.M.J. Vanderschuren
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Specific Manner ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals Deep Brain Stimulation of the ventral striatum impairs extinction of morphine place preference (LB76)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Janelle Miranda ◽  
Freddyson Martinez ◽  
José Rodríguez ◽  
Fabricio Do Monte ◽  
Oscar Muñiz ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Place Preference ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals Weight Change after Striatal/Capsule Deep Brain Stimulation Relates to Connectivity to the Bed Nucleus of the Stria Terminalis and Hypothalamus

2019 ◽  
Vol 9 (10) ◽  
pp. 264 ◽  
Author(s):  
Juan Baldermann ◽  
Lisa Hahn ◽  
Till Dembek ◽  
Sina Kohl ◽  
Jens Kuhn ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Food Intake ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Therapeutic Potential ◽  
Weight Changes ◽  
Bed Nucleus ◽  
Compulsive Disorder ◽  
Deep Brain ◽  
Stimulation Of

Weight changes are insufficiently understood adverse events of deep brain stimulation. In this context, exploring neural networks of weight control may inform novel treatment strategies for weight-related disorders. In this study, we investigated weight changes after deep brain stimulation of the ventral striatum/ventral capsule and to what extent changes are associated with connectivity to feeding-related networks. We retrospectively analyzed 25 patients undergoing deep brain stimulation for obsessive-compulsive disorder or substance dependency. Weight changes were assessed preoperatively and six to twelve months after surgery and then matched with individual stimulation sites and stimulation-dependent functional connectivity to a priori defined regions of interest that are involved in food intake. We observed a significant weight gain after six to twelve months of continuous stimulation. Weight increases were associated with medial/apical localization of stimulation sites and with connectivity to hypothalamic areas and the bed nucleus. Thus, deep brain stimulation of the ventral striatum/ventral capsule influences weight depending on localization and connectivity of stimulation sites. Bearing in mind the significance of weight-related disorders, we advocate further prospective studies investigating the neuroanatomical and neuropsychological underpinnings of food intake and their neuromodulatory therapeutic potential.

scholarly journals Deep brain stimulation of the ventral striatum increases BDNF in the fear extinction circuit

2013 ◽  
Vol 7 ◽  
Author(s):  
Fabricio H. Do-Monte ◽  
Jose Rodriguez-Romaguera ◽  
Luis E. Rosas-Vidal ◽  
Gregory J. Quirk
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Fear Extinction ◽  
Deep Brain ◽  
Stimulation Of
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