scholarly journals Growth of cortical bone thickness and trabecular bone density in Japanese children

Bone ◽  
2020 ◽  
Vol 141 ◽  
pp. 115669
Author(s):  
Etsuko Ozaki ◽  
Mami Matsukawa ◽  
Isao Mano ◽  
Daisuke Matsui ◽  
Yutaro Yoneda ◽  
...  
Keyword(s):  
Bone Density ◽  
Trabecular Bone ◽  
Cortical Bone ◽  
Trabecular Bone Density ◽  
Bone Thickness ◽  
Japanese Children ◽  
Cortical Bone Thickness

scholarly journals POS1092 SUBCHONDRAL BONE NORMALIZATION AFTER KNEE JOINT DISTRACTION TREATMENT AS MEASURED WITH CT

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 825.2-826
Author(s):  
M. Jansen ◽  
A. Ooms ◽  
T. D. Turmezei ◽  
J. W. Mackay ◽  
S. Mastbergen ◽  
...  
Keyword(s):  
Bone Density ◽  
Trabecular Bone ◽  
Cortical Bone ◽  
Subchondral Bone ◽  
Trabecular Bone Density ◽  
Bone Thickness ◽  
Cortical Bone Thickness ◽  
Bone Changes ◽  
One Year ◽  
Shape Changes

Background:In addition to cartilage degeneration, knee osteoarthritis (OA) causes bone changes, including cortical bone thickening, subchondral bone density decrease, and bone shape changes as a result of widening and flattening condyles and osteophyte formation. Knee joint distraction (KJD) is a joint-preserving treatment for younger (<65 years) knee OA patients that has been shown to reverse OA cartilage degradation. On radiographs, KJD showed a decrease in subchondral bone density and an increase in osteophyte formation. However, these bone changes have never been evaluated with a 3D imaging technique.Objectives:To evaluate cortical bone thickness, subchondral trabecular bone density, and bone shape on CT scans before and one year after KJD treatment.Methods:19 KJD patients were included in an extended imaging protocol, undergoing a CT scan before and one year after treatment. Stradview v6.0 was used for semi-automatic tibia and femur segmentation from axial thin-slice (0.45mm) CT scans. Cortical bone thickness (mm) and trabecular bone density (Hounsfield units, HU) were measured with an automated algorithm. Osteophytes were excluded. Afterwards, wxRegSurf v18 was used for surface registration. Registration data was used for bone shape measurements. MATLAB R2020a and the SurfStat MATLAB package were used for data analysis and visualization. Two-tailed F-tests were used to calculate changes over time. Two separate linear regression models were used to show the influence of baseline Kellgren-Lawrence grade and sex on the changes over time. Statistical significance was calculated with statistical parametric mapping; a p-value <0.05 was considered statistically significant. Bone shape changes were explored visually using vertex by vertex displacements between baseline and follow-up. Patients were separated into two groups based on whether their most affected compartment (MAC) was medial or lateral. Only patients with axial CT scans at both time points available for analysis were included for evaluation.Results:3 Patients did not have complete CTs and in 1 patient the imaged femur was too short, leaving 16 patients for tibial analyses and 15 patients for femoral analyses. The MAC was predominantly the medial side (medial MAC n=14; lateral n=2). Before treatment, the MAC cortical bone was compared to the rest of the joint (Figure 1). One year after treatment, MAC cortical thickness decreased, although this decrease of up to approximately 0.25 mm was not statistically significant. The trabecular bone density was also higher before treatment in the MAC, and a decrease was seen throughout the entire joint, although statistically significant only for small areas on mostly the MAC where this decrease was up to approximately 80 HU (Figure 1). Female patients and patients with a higher Kellgren-Lawrence grade showed a somewhat larger decrease in cortical bone thickness. Trabecular density decreased less for patients with a higher Kellgren-Lawrence grade, and female patients showed a higher density decrease interiorly while male patients showed a higher decrease exteriorly. None of this was statistically significant. The central areas of both compartments showed an outward shape change, while the outer ring showed inward changes.Conclusion:MAC cortical bone thickness shows a partial decrease after KJD. Trabecular bone density decreased on both sides of the joint, likely as a direct result of the bicompartmental unloading. For both subchondral bone parameters, MAC values became more similar to the LAC, indicating (partial) subchondral bone normalization in the most affected parts of the joint. The bone shape changes may indicate a reversal of typical OA changes, although the inward difference that was seen on the outer edges may be a result of osteophyte-related changes that might have affected the bone segmentation. In conclusion, KJD treatment shows subchondral bone normalization in the first year after treatment, and longer follow-up might show whether these changes are a temporary result of joint unloading or indicate more prolonged bone changes.Disclosure of Interests:None declared.

scholarly journals Effects of cortical bone thickness and trabecular bone density on primary stability of orthodontic mini-implants

2019 ◽  
Vol 14 (4) ◽  
pp. 383-388
Author(s):  
Chin-Yun Pan ◽  
Pao-Hsin Liu ◽  
Yu-Chuan Tseng ◽  
Szu-Ting Chou ◽  
Chao-Yi Wu ◽  
...  
Keyword(s):  
Bone Density ◽  
Trabecular Bone ◽  
Cortical Bone ◽  
Primary Stability ◽  
Trabecular Bone Density ◽  
Bone Thickness ◽  
Cortical Bone Thickness ◽  
Mini Implants

scholarly journals Relationship between Cortical Bone Thickness and Cancellous Bone Density at Dental Implant Sites in the Jawbone

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 710
Author(s):  
Shiuan-Hui Wang ◽  
Yen-Wen Shen ◽  
Lih-Jyh Fuh ◽  
Shin-Lei Peng ◽  
Ming-Tzu Tsai ◽  
...  
Keyword(s):  
Bone Density ◽  
Cortical Bone ◽  
Dental Implant ◽  
Cancellous Bone ◽  
Bone Thickness ◽  
Anterior Maxilla ◽  
Cortical Bone Thickness ◽  
Posterior Maxilla ◽  
Dental Implant Surgery ◽  
Anterior Mandible

Dental implant surgery is a common treatment for missing teeth. Its survival rate is considerably affected by host bone quality and quantity, which is often assessed prior to surgery through dental cone-beam computed tomography (CBCT). Dental CBCT was used in this study to evaluate dental implant sites for (1) differences in and (2) correlations between cancellous bone density and cortical bone thickness among four regions of the jawbone. In total, 315 dental implant sites (39 in the anterior mandible, 42 in the anterior maxilla, 107 in the posterior mandible, and 127 in the posterior maxilla) were identified in dental CBCT images from 128 patients. All CBCT images were loaded into Mimics 15.0 to measure cancellous bone density (unit: grayscale value (GV) and cortical bone thickness (unit: mm)). Differences among the four regions of the jawbone were evaluated using one-way analysis of variance and Scheffe’s posttest. Pearson coefficients for correlations between cancellous bone density and cortical bone thickness were also calculated for the four jawbone regions. The results revealed that the mean cancellous bone density was highest in the anterior mandible (722 ± 227 GV), followed by the anterior maxilla (542 ± 208 GV), posterior mandible (535 ± 206 GV), and posterior maxilla (388 ± 206 GV). Cortical bone thickness was highest in the posterior mandible (1.15 ± 0.42 mm), followed by the anterior mandible (1.01 ± 0.32 mm), anterior maxilla (0.89 ± 0.26 mm), and posterior maxilla (0.72 ± 0.19 mm). In the whole jawbone, a weak correlation (r = 0.133, p = 0.041) was detected between cancellous bone density and cortical bone thickness. Furthermore, except for the anterior maxilla (r = 0.306, p = 0.048), no correlation between the two bone parameters was observed (all p > 0.05). Cancellous bone density and cortical bone thickness varies by implant site in the four regions of the jawbone. The cortical and cancellous bone of a jawbone dental implant site should be evaluated individually before surgery.

Turner's syndrome is associated with reduced cortical bone density with preservation of trabecular bone density

Bone ◽  
2009 ◽  
Vol 45 ◽  
pp. S55-S56
Author(s):  
C. Holroyd ◽  
P. Taylor ◽  
C. Rivett ◽  
K. Jameson ◽  
C. Cooper ◽  
...  
Keyword(s):  
Bone Density ◽  
Trabecular Bone ◽  
Cortical Bone ◽  
Turner's Syndrome ◽  
Trabecular Bone Density ◽  
Turner’S Syndrome ◽  
Cortical Bone Density

scholarly journals Bone microarchitecture and estimated bone strength in men with active acromegaly

2017 ◽  
Vol 177 (5) ◽  
pp. 409-420 ◽  
Author(s):  
Paula P B Silva ◽  
Fatemeh G Amlashi ◽  
Elaine W Yu ◽  
Karen J Pulaski-Liebert ◽  
Anu V Gerweck ◽  
...  
Keyword(s):  
Bone Density ◽  
Trabecular Bone ◽  
Cortical Bone ◽  
Bone Strength ◽  
Bone Microarchitecture ◽  
Healthy Controls ◽  
Trabecular Bone Density ◽  
Trabecular Bone Microarchitecture ◽  
Skeletal Site ◽  
Active Acromegaly

Context Both acromegaly and adult growth hormone deficiency (GHD) are associated with increased fracture risk. Sufficient data are lacking regarding cortical bone microarchitecture and bone strength, as assessed by microfinite element analysis (µFEA). Objective To elucidate both cortical and trabecular bone microarchitecture and estimated bone strength in men with active acromegaly or GHD compared to healthy controls. Design and subjects Cross-sectional study at a clinical research center, including 48 men (16 with acromegaly, 16 with GHD and 16 healthy controls). Outcome measures Areal bone mineral density (aBMD), cortical and trabecular bone microarchitecture and estimated bone strength (µFEA) at the radius and tibia. Results aBMD was not different between the 3 groups at any skeletal site. At the radius, patients with acromegaly had greater cortical area (P < 0.0001), cortical thickness (P = 0.0038), cortical pore volume (P < 0.0001) and cortical porosity (P = 0.0008), but lower trabecular bone density (P = 0.0010) compared to controls. At the tibia, patients with acromegaly had lower trabecular bone density (P = 0.0082), but no differences in cortical bone microstructure. Compressive strength and failure load did not significantly differ between groups. These findings persisted after excluding patients with hypogonadism. Bone microarchitecture was not deficient in patients with GHD. Conclusions Both cortical and trabecular microarchitecture are altered in men with acromegaly. Our data indicate that GH excess is associated with distinct effects in cortical vs trabecular bone compartments. Our observations also affirm the limitations of aBMD testing in the evaluation of patients with acromegaly.

scholarly journals Bone Density and Cortical Thickness in Normal, Osteopenic, and Osteoporotic Sacra

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Andrew M. Richards ◽  
Nathan W. Coleman ◽  
Trevor A. Knight ◽  
Stephen M. Belkoff ◽  
Simon C. Mears
Keyword(s):  
Bone Density ◽  
Cortical Bone ◽  
Cortical Thickness ◽  
Cancellous Bone ◽  
Quantitative Computed Tomography ◽  
Insufficiency Fractures ◽  
Bone Thickness ◽  
Cortical Bone Thickness ◽  
Local Reduction ◽  
Sacral Insufficiency Fractures

It is unclear if a decrease in cancellous bone density or cortical bone thickness is related to sacral insufficiency fractures. We hypothesized that reduction in overall bone density leads to local reductions in bone density and cortical thickness in cadaveric sacra that match clinically observed fracture patterns in patients with sacral insufficiency fractures. We used quantitative computed tomography to measure cancellous density and cortical thickness in multiple areas of normal, osteopenic, and osteoporotic sacra. Cancellous bone density was significantly lower in osteoporotic specimens in the central and anterior regions of the sacral ala compared with other regions of these specimens. Cortical thickness decreased uniformly in all regions of osteopenic and osteoporotic specimens. These results support our hypothesis that areas of the sacrum where sacral insufficiency fractures often occur have significantly larger decreases in cancellous bone density; however, they do not support the hypothesis that these areas have local reduction of cortical bone thickness.

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