scholarly journals Declining incidence trends for hip fractures have not been accompanied by improvements in lifetime risk or post-fracture survival – A nationwide study of the Swedish population 60years and older

Bone ◽  
2015 ◽  
Vol 78 ◽  
pp. 55-61 ◽  
Author(s):  
Korinna Karampampa ◽  
Anders Ahlbom ◽  
Karl Michaëlsson ◽  
Tomas Andersson ◽  
Sven Drefahl ◽  
...  
Author(s):  
John Berntsson ◽  
Xinjun Li ◽  
Bengt Zöller ◽  
Andreas Martinsson ◽  
Pontus Andell ◽  
...  

Background It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF . Methods and Results In this nationwide study of the Swedish population, patients with AF and their siblings were identified from the Swedish patient registers and the Swedish MGR (Multi‐Generation Register). Ischemic stroke events were retrieved from the Swedish patient registers and CDR (Cause of Death Register). Risk of ischemic stroke was compared between patients with AF with and without a sibling affected by ischemic stroke, AF , or both ischemic stroke and AF . The total study population comprised 113 988 subjects (mean age, 60±12 years) diagnosed with AF between 1989 and 2012. In total, 11 709 of them were diagnosed with a first ischemic stroke and 20 097 died during a mean follow‐up time of 5.5 years for ischemic stroke and 5.9 years for mortality. After adjustment for covariates having a sibling with ischemic stroke, or both ischemic stroke and AF , was associated with increased risk of ischemic stroke (hazard ratio, 1.31; 95% CI, 1.23–1.40 or hazard ratio, 1.36; 95% CI , 1.24–1.49, respectively). Furthermore, ischemic stroke in a sibling was associated with all‐cause mortality (hazard ratio, 1.09; 95% CI , 1.05–1.14). In contrast, the risk of stroke was only marginally increased for patients with AF with a spouse affected by ischemic stroke. Conclusions Having a sibling affected by ischemic stroke confers an increased risk of ischemic stroke and death independently of traditional risk factors in patients with AF.


2014 ◽  
Vol 71 (5) ◽  
pp. 573 ◽  
Author(s):  
Carsten Bøcker Pedersen ◽  
Ole Mors ◽  
Aksel Bertelsen ◽  
Berit Lindum Waltoft ◽  
Esben Agerbo ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Darja Urlep ◽  
Rok Blagus ◽  
Rok Orel

Background. The aims of the study were to determine the incidence rate of pediatric inflammatory bowel disease (PIBD) and its trends for the period of 2002–2010 and to assess the geographical distribution of PIBD in Slovenia.Materials and Methods. Medical records of patients (0–18 years) with newly diagnosed IBD during the study period were retrospectively reviewed.Results. The mean incidence rate for IBD in 2002–2010 was 7.6 per 100,000 children and adolescents per year, 4.5 for Crohn’s disease (CD), 2.9 for ulcerative colitis (UC), and 0.2 for IBD-unclassified, respectively. The incidence rate increased from 5.8 per 100,000 per year in 2002–2004 to 8.6 in 2005–2007 and remained stable afterwards. Statistically significant difference in the incidence rate between the Northeastern and Southwestern parts of the country was observed (p=0.025).Conclusion. This nationwide study demonstrates that Slovenia is among the European countries with the highest PIBD incidence. During the study period a substantial rise of PIBD incidence was observed during the first half of the study and it seems to have stabilized in the second half. The significant difference in PIBD incidence between Northeastern and Southwestern parts of the country merits further exploration of the possible environmental factors.


2011 ◽  
Vol 17 (8) ◽  
pp. 1778-1783 ◽  
Author(s):  
Pieta Lehtinen ◽  
Merja Ashorn ◽  
Sari Iltanen ◽  
Raimo Jauhola ◽  
Pekka Jauhonen ◽  
...  

1998 ◽  
Vol 8 (6) ◽  
pp. 599-603 ◽  
Author(s):  
A. Oden ◽  
A. Dawson ◽  
W. Dere ◽  
O. Johnell ◽  
B. Jonsson ◽  
...  
Keyword(s):  

2021 ◽  
Vol 184 (2) ◽  
pp. 209-216
Author(s):  
Konstantina Vouzouneraki ◽  
Daniela Esposito ◽  
Sebastian Mukka ◽  
Daniel Granfeldt ◽  
Oskar Ragnarsson ◽  
...  

Objective Carpal tunnel syndrome (CTS) is common in patients with acromegaly, with a reported prevalence of 19–64%. We studied CTS in a large national cohort of patients with acromegaly and the temporal relationship between the two diagnoses. Design Retrospective, nationwide, cohort study including patients diagnosed with acromegaly in Sweden, 2005–2017, identified in the Swedish Healthcare Registries. Methods CTS (diagnosis and surgery in specialised healthcare) was analysed from 8.5 years before the diagnosis of acromegaly until death or end of the study. Standardised incidence ratios (SIRs) with 95% CIs were calculated for CTS with the Swedish population as reference. Results The analysis included 556 patients with acromegaly (50% women) diagnosed at mean (s.d.) age 50.1 (15.0) years. During the study period, 48 patients were diagnosed with CTS and 41 patients underwent at least one CTS surgery. In the latter group, 35 (85%) were operated for CTS before the acromegaly diagnosis; mean interval (range) 2.2 (0.3–8.5) years and the SIR for having CTS surgery before the diagnosis of acromegaly was 6.6 (4.8–8.9). Women with acromegaly had a higher risk for CTS than men (hazard ratio: 2.5, 95% CI: 1.3–4.7). Conclusions Patients with acromegaly had a 6-fold higher incidence for CTS surgery before the diagnosis of acromegaly compared with the general population. The majority of patients with both diagnoses were diagnosed with CTS prior to acromegaly. Increased awareness of signs of acromegaly in patients with CTS might help to shorten the diagnostic delay in acromegaly, especially in women.


HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 826-827
Author(s):  
P. Johansson ◽  
C. Lewerin ◽  
H. Kristjansdottir ◽  
H. Johansson ◽  
D. Mellström

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