Methods and reliability of radiographic vertebral fracture detection in older men; methodological issues to avoid misinterpretation

Bone ◽  
2015 ◽  
Vol 75 ◽  
pp. 244-245 ◽  
Author(s):  
Siamak Sabour
Bone ◽  
2014 ◽  
Vol 67 ◽  
pp. 152-155 ◽  
Author(s):  
Peggy M. Cawthon ◽  
Jane Haslam ◽  
Robin Fullman ◽  
Katherine W. Peters ◽  
Dennis Black ◽  
...  

Rheumatology ◽  
2020 ◽  
Author(s):  
Anaïs Guiot ◽  
Charline Estublier ◽  
Marine Gaude ◽  
Pawel Szulc ◽  
Roland Chapurlat

Abstract Objective To analyse the risk of incident vertebral and non-vertebral fracture in men with DISH. Methods In 782 men ages 50–85 years, DISH was diagnosed using Resnick’s criteria. In men followed prospectively for 7.5 years, a radiographic incident vertebral fracture was defined by a decrease of ≥20% or ≥4mm in any vertebral height vs baseline. Self-reported incident non-vertebral fractures were confirmed by medical records. Results Men with DISH had higher BMD at the lumbar spine (P < 0.05), but not at other skeletal sites. After adjustment for confounders including disc space narrowing (DSN) and endplate irregularity, the risk of vertebral fracture was higher in men with DISH vs men without DISH [10/164 (6.1%) vs 16/597 (2.7%), P < 0.05; odds ratio (OR) 2.89 (95% CI 1.15, 7.28), P < 0.05]. DISH and low spine BMD were each associated with a higher vertebral fracture risk. The vertebral fracture risk was higher in men who had both DISH and severe DSN. DISH and endplate irregularities (EIs) were each associated with higher vertebral fracture risk. DISH, DSN and EIs define the intervertebral space dysfunction, which was associated with higher vertebral fracture risk [OR 3.99 (95% CI 1.45, 10.98), P < 0.01]. Intervertebral space dysfunction improved the vertebral fracture prediction (ΔAUC = +0.111, P < 0.05), mainly in men with higher spine BMD (>0.9 g/cm2; ΔAUC = +0.189, P < 0.001). DISH was not associated with the risk of non-vertebral fracture. Conclusion DISH is associated with higher vertebral fracture risk, independently of other risk factors. Assessment of the intervertebral space dysfunction components may improve the vertebral fracture prediction in older men.


2007 ◽  
Vol 14 (10) ◽  
pp. 1166-1178 ◽  
Author(s):  
Martin Roberts ◽  
Tim Cootes ◽  
Elisa Pacheco ◽  
Judith Adams

2015 ◽  
Vol 31 (3) ◽  
pp. 690-697 ◽  
Author(s):  
John T Schousboe ◽  
Tien Vo ◽  
Brent C Taylor ◽  
Peggy M Cawthon ◽  
Ann V Schwartz ◽  
...  

2019 ◽  
Vol 35 (3) ◽  
pp. 460-468
Author(s):  
Jinhui Ma ◽  
Kerry Siminoski ◽  
Peiyao Wang ◽  
Nathalie Alos ◽  
Elizabeth A Cummings ◽  
...  

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