An experiment on in vitro bone tissue formation by HMS0014 human mesenchymal cells cultured on surface modified titanium plates

Bone ◽  
2012 ◽  
Vol 51 (6) ◽  
pp. S17
Author(s):  
M. Nakatsuka ◽  
S. Kumabe ◽  
Y. Hashimoto ◽  
A. Hosoya ◽  
C. An ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Mesenchymal Cells ◽  
Tissue Formation ◽  
Surface Modified ◽  
Bone Tissue Formation ◽  
Cells Cultured

Bioactive and Biocompatible Silica/Pseudowollastonite Aerogels

2014 ◽  
Vol 96 ◽  
pp. 21-26 ◽  
Author(s):  
P.J. Reséndiz-Hernández ◽  
D.A. Cortés-Hernández ◽  
Juan Méndez Nonell ◽  
J.C. Escobedo-Bocardo
Keyword(s):  
Bone Tissue ◽  
Ambient Pressure ◽  
Sol Gel ◽  
Ambient Pressure Drying ◽  
Bone Tissue Regeneration ◽  
Tissue Formation ◽  
Potential Applications ◽  
Ft Ir ◽  
Bone Tissue Formation

Silica aerogels have attracted increasingly more attention due to their extraordinary properties and their existing and potential applications in a wide variety of technological areas. Materials that promote bone-tissue formation at their surface and bond to osseous tissues when implanted are called bioactive, such as pseudowollastonite particles. In this work, the synthesis of aerogels with pseudowollastonite particles was performed. The synthesis involved the preparation of an alcogel by a two step sol-gel route followed by ambient pressure drying. To promote a higher bioactivity the obtained aerogels were then biomimetically treated using simulated body fluids, SBF and 1.5 SBF. A high bioactivity was demonstrated by FT-IR, SEM, EDS, and XRD. The in vitro biocompatibility was assessed by testing cytotoxicity using rat osteoblasts cultures. The results obtained indicate that these materials are highly potential aerogels for bone tissue regeneration.

Carbon Nanotube Reinforced Collagen/Hydroxyapatite Scaffolds Improve Bone Tissue Formation In Vitro and In Vivo

2017 ◽  
Vol 45 (9) ◽  
pp. 2075-2087 ◽  
Author(s):  
Zheng Jing ◽  
Yeke Wu ◽  
Wen Su ◽  
Mi Tian ◽  
Wenlu Jiang ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Bone Tissue ◽  
Tissue Formation ◽  
Bone Tissue Formation

scholarly journals Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model

2014 ◽  
pp. 4277 ◽  
Author(s):  
Antonio Barrientos-Duran ◽  
Ellen M. Carpenter ◽  
Nicole I. zur Nieden ◽  
Theodore I. Malinin ◽  
Juan Carlos Rodriguez-Manzaneque ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Bone Tissue ◽  
Rat Model ◽  
Single Wall Carbon Nanotubes ◽  
Tissue Formation ◽  
Single Wall Carbon ◽  
Bone Tissue Formation

scholarly journals Vascularized Bone Tissue Formation Induced by Fiber-Reinforced Scaffolds Cultured with Osteoblasts and Endothelial Cells

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Xinhui Liu ◽  
Guoping Zhang ◽  
Chuanyong Hou ◽  
Hua Wang ◽  
Yelin Yang ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Bone Tissue ◽  
Bone Repair ◽  
Composite Scaffold ◽  
Tissue Formation ◽  
General Observation ◽  
Repair Materials ◽  
Bone Tissue Formation ◽  
Vascularized Bone

The repair of the damaged bone tissue caused by damage or bone disease was still a problem. Current strategies including the use of autografts and allografts have the disadvantages, namely, diseases transmission, tissue availability and donor morbidity. Bone tissue engineering has been developed and regarded as a new way of regenerating bone tissues to repair or substitute damaged or diseased ones. The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel system, the vascularization. In this paper, a new-typed hydroxyapatite/collagen composite scaffold which was reinforced by chitosan fibers and cultured with osteoblasts and endothelial cells was fabricated. General observation, histological observation, detection of the degree of vascularization, and X-ray examination had been done to learn the effect of vascularized bone repair materials on the regeneration of bone. The results show that new vessel and bone formed using implant cultured with osteoblasts and endothelial cells. Nanofiber-reinforced scaffold cultured with osteoblasts and endothelial cells can induce vascularized bone tissue formation.

55S® Bioglass Stimulates in Vitro Osteoblast Differentiation and Creates a Favorable Template for Bone Tissue Formation

2000 ◽  
Vol 192-195 ◽  
pp. 605-608
Author(s):  
S. Loty ◽  
J.M. Sautier ◽  
C. Loty ◽  
M.T. Tan ◽  
D.C. Greenspan ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Osteoblast Differentiation ◽  
Tissue Formation ◽  
Bone Tissue Formation

Nanomaterial-based scaffolds for bone tissue engineering and regeneration

Nanomedicine ◽  
2020 ◽  
Vol 15 (20) ◽  
pp. 1995-2017
Author(s):  
Guo Ye ◽  
Fangyuan Bao ◽  
Xianzhu Zhang ◽  
Zhe Song ◽  
Youguo Liao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Bone Tissue Regeneration ◽  
Tissue Formation ◽  
Topological Features ◽  
Potential Risks ◽  
Underlying Mechanisms ◽  
Nanocomposite Scaffolds ◽  
Bone Tissue Formation

The global incidence of bone tissue injuries has been increasing rapidly in recent years, making it imperative to develop suitable bone grafts for facilitating bone tissue regeneration. It has been demonstrated that nanomaterials/nanocomposites scaffolds can more effectively promote new bone tissue formation compared with micromaterials. This may be attributed to their nanoscaled structural and topological features that better mimic the physiological characteristics of natural bone tissue. In this review, we examined the current applications of various nanomaterial/nanocomposite scaffolds and different topological structures for bone tissue engineering, as well as the underlying mechanisms of regeneration. The potential risks and toxicity of nanomaterials will also be critically discussed. Finally, some considerations for the clinical applications of nanomaterials/nanocomposites scaffolds for bone tissue engineering are mentioned.

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