25-hydroxyvitamin D3 treatment normalize the vitamin D status and the innate immune response mediated by cathelicidin in critically ill patients

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S146-S147 ◽  
Author(s):  
J. Vargas-Vasserot ◽  
J.M. Mata-Granados ◽  
M. Luque de Castro ◽  
R. Guerrero Pavón ◽  
J. Quesada Gomez
Keyword(s):  
Vitamin D ◽  
Immune Response ◽  
Critically Ill ◽  
Innate Immune Response ◽  
Critically Ill Patients ◽  
Innate Immune ◽  
Vitamin D Status

The Effects of Brain Injury on Heart Rate Variability and the Innate Immune Response in Critically Ill Patients

2012 ◽  
Vol 29 (5) ◽  
pp. 747-755 ◽  
Author(s):  
Matthijs Kox ◽  
Maarten Q. Vrouwenvelder ◽  
Jan C. Pompe ◽  
Johannes G. van der Hoeven ◽  
Peter Pickkers ◽  
...  
Keyword(s):  
Heart Rate ◽  
Immune Response ◽  
Heart Rate Variability ◽  
Brain Injury ◽  
Critically Ill ◽  
Innate Immune Response ◽  
Critically Ill Patients ◽  
Innate Immune

scholarly journals Acute Kidney Injury Induces Innate Immune Response and Neutrophil Activation in the Lung

2020 ◽  
Vol 7 ◽  
Author(s):  
Akinori Maeda ◽  
Naoki Hayase ◽  
Kent Doi
Keyword(s):  
Immune Response ◽  
Acute Kidney Injury ◽  
Critically Ill ◽  
Innate Immune Response ◽  
Critically Ill Patients ◽  
Ischemia Reperfusion ◽  
Kidney Injury ◽  
Neutrophil Activation ◽  
Innate Immune ◽  
Organ Crosstalk

Complication in acute kidney injury (AKI) is significantly associated with developing acute respiratory failure (ARF), while ARF is one of the most important risks for AKI. These data suggest AKI and ARF may synergistically worsen the outcomes of critically ill patients and these organ injuries may not occur independently. Organ crosstalk between the kidney and the lung has been investigated by using animal models so far. This review will focus on innate immune response and neutrophil activation among the mechanisms that contribute to this organ crosstalk. AKI increased the blood level of an inflammatory mediator in high-mobility group box 1, which induces an innate immune reaction via toll-like receptor 4. The remarkable infiltration of neutrophils to the lung was observed in animal AKI models. IL-6 and IL-8 have been demonstrated to contribute to pulmonary neutrophil activation in AKI. In addition, the formation of a neutrophil extracellular trap was also observed in the lung after the exposure of renal ischemia reperfusion in the animal model. Further investigation is necessary to determine whether targeting innate immune response and neutrophil activation will be useful for developing new therapeutics that could improve multiple organ failure in critically ill patients.

scholarly journals Vitamin D status and overall and sepsis mortality in critically ill patients

Critical Care ◽  
2013 ◽  
Vol 17 (S2) ◽  
Author(s):  
P Zajic ◽  
C Schnedl ◽  
T Valentin ◽  
A Grisold ◽  
A Holl ◽  
...  
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status ◽  
Sepsis Mortality

MON-PO611: Vitamin D Status and Inflammatory Bio-Markers in Critically Ill Patients with Sepsis

2019 ◽  
Vol 38 ◽  
pp. S285-S286
Author(s):  
L.S. Alnasrallah ◽  
M.M.A. Abulmeaty ◽  
A.M. Almajwal ◽  
Y. Arabi ◽  
H. Aldorzih ◽  
...  
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status

scholarly journals Respond to Vitamin D status in adult critically ill patients in Eastern India: An observational retrospective study

Lung India ◽  
2015 ◽  
Vol 32 (2) ◽  
pp. 201
Author(s):  
Rajesh Padhi ◽  
Baikunthanath Panda ◽  
Snehalata Jagati ◽  
SubhasChandra Patra
Keyword(s):  
Vitamin D ◽  
Retrospective Study ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status ◽  
Eastern India

scholarly journals The impact of vitamin D on the innate immune response to uropathogenic Escherichia coli during pregnancy

2015 ◽  
Vol 21 (5) ◽  
pp. 482.e1-482.e7 ◽  
Author(s):  
N.L. Ramos ◽  
M. Sekikubo ◽  
F. Kironde ◽  
F. Mirembe ◽  
M. Sääf ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Vitamin D ◽  
Immune Response ◽  
Innate Immune Response ◽  
Uropathogenic Escherichia Coli ◽  
Innate Immune ◽  
The Impact
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