Sost down-regulation following mechanical strain in human osteoblastic cells in vitro involves the PGE2/EP4 and ERK signalling pathways

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S109 ◽  
Author(s):  
G.L. Galea ◽  
A. Sunters ◽  
L.E. Lanyon ◽  
J.S. Price
Keyword(s):  
Mechanical Strain ◽  
Osteoblastic Cells ◽  
Signalling Pathways ◽  
Down Regulation ◽  
Human Osteoblastic Cells

scholarly journals Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

FEBS Letters ◽  
2011 ◽  
Vol 585 (15) ◽  
pp. 2450-2454 ◽  
Author(s):  
Gabriel L. Galea ◽  
Andrew Sunters ◽  
Lee B. Meakin ◽  
Gul Zaman ◽  
Toshihiro Sugiyama ◽  
...  
Keyword(s):  
Mechanical Strain ◽  
Osteoblastic Cells ◽  
Down Regulation ◽  
Human Osteoblastic Cells

Cultures of human osteoblastic cells from dialysis patients: Influence of bone turnover rate on in vitro secretion of interleukin-6 and osteoblastic cell markers

2001 ◽  
Vol 37 (1) ◽  
pp. 30-37 ◽  
Author(s):  
M. Carmen Sánchez ◽  
M. Auxiliadora Bajo ◽  
Rafael Selgas ◽  
Alberto Mate ◽  
M. Jesús Sánchez-Cabezudo ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Interleukin 6 ◽  
Turnover Rate ◽  
Osteoblastic Cells ◽  
Osteoblastic Cell ◽  
Dialysis Patients ◽  
Cell Markers ◽  
Human Osteoblastic Cells

Human cementum tumor cells have different features from human osteoblastic cells in vitro

1998 ◽  
Vol 33 (5) ◽  
pp. 249-258 ◽  
Author(s):  
Higinio Arzate ◽  
Marco A. Alvarez-Perez ◽  
Ma. Eugenia Aguilar-Mendoza ◽  
Octavio Alvarez-Fregoso
Keyword(s):  
Tumor Cells ◽  
Osteoblastic Cells ◽  
Human Osteoblastic Cells

In vitro evaluation of dose-effects of ethanol on human osteoblastic cells

1993 ◽  
Vol 22 (2) ◽  
pp. 95-103 ◽  
Author(s):  
Pascale Chavassieux ◽  
Claire Marie Serre ◽  
Philippe Vergnaud ◽  
Pierre D. Delmas ◽  
Pierre J. Meunier
Keyword(s):  
Osteoblastic Cells ◽  
In Vitro Evaluation ◽  
Dose Effects ◽  
Human Osteoblastic Cells

Prosthetic particles modify the expression of bone-related proteins by human osteoblastic cells in vitro

Biomaterials ◽  
2003 ◽  
Vol 24 (2) ◽  
pp. 337-346 ◽  
Author(s):  
H. Zreiqat ◽  
T.N. Crotti ◽  
C.R. Howlett ◽  
M. Capone ◽  
B. Markovic ◽  
...  
Keyword(s):  
Osteoblastic Cells ◽  
Related Proteins ◽  
Human Osteoblastic Cells

scholarly journals Factorial Study of Compressive Mechanical Properties and PrimaryIn VitroOsteoblast Response of PHBV/PLLA Scaffolds

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Naznin Sultana ◽  
Tareef Hayat Khan
Keyword(s):  
Mechanical Properties ◽  
Polymer Matrix ◽  
Tissue Regeneration ◽  
Degradation Rate ◽  
Bone Tissue Regeneration ◽  
Osteoblastic Cells ◽  
Composite Scaffolds ◽  
Biomimetic Systems ◽  
Human Osteoblastic Cells

For bone tissue regeneration, composite scaffolds containing biodegradable polymers and nanosized osteoconductive bioceramics have been regarded as promising biomimetic systems. Polymer blends of poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) and poly(L-lactic acid) (PLLA) can be used as the polymer matrix to control the degradation rate. In order to render the scaffolds osteoconductive, nano-sized hydroxyapatite (nHA) particles can be incorporated into the polymer matrix. In the first part of this study, a factorial design approach to investigate the influence of materials on the initial compressive mechanical properties of the scaffolds was studied. In the second part, the protein adsorption behavior and the attachment and morphology of osteoblast-like cells (Saos-2) of the scaffoldsin vitrowere also studied. It was observed that nHA incorporated PHBV/PLLA composite scaffolds adsorbed more bovine serum albumin (BSA) protein than PHBV or PHBV/PLLA scaffolds.In vitrostudies also revealed that the attachment of human osteoblastic cells (SaOS-2) was significantly higher in nHA incorporated PHBV/PLLA composite scaffolds. From the SEM micrographs of nHA incorporated PHBV/PLLA composite scaffolds seeded with SaOS-2 cells after a 7-day cell culture period, it was observed that the cells were well expanded and spread in all directions on the scaffolds.

scholarly journals Evaluation of the direct effects of poly(dopamine) on the in vitro response of human osteoblastic cells

2016 ◽  
Vol 4 (18) ◽  
pp. 3145-3156 ◽  
Author(s):  
Alexander J. Steeves ◽  
Aman Atwal ◽  
Sarah C. Schock ◽  
Fabio Variola
Keyword(s):  
Osteoblastic Cells ◽  
Direct Effects ◽  
Efficient Strategy ◽  
Bioactive Properties ◽  
In Vitro Response ◽  
Human Osteoblastic Cells

Functional poly(dopamine) coatings promise to become an efficient strategy to endow biomaterials with enhanced bioactive properties.

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