Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A 2 inhibitors––reducing the lipophilicity of the arachidonyl chain isostere

2004 ◽  
Vol 14 (14) ◽  
pp. 3645-3649 ◽  
Author(s):  
Iain Walters ◽  
Colin Bennion ◽  
Stephen Connolly ◽  
Pamela J Croshaw ◽  
Kim Hardy ◽  
...  
Keyword(s):  
Phospholipase A ◽  
Cytosolic Phospholipase ◽  
Phospholipase A 2

Cytosolic phospholipase A 2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid‐β peptide

2004 ◽  
Vol 19 (1) ◽  
pp. 85-87 ◽  
Author(s):  
Badreddine Kriem ◽  
Isabelle Sponne ◽  
Alexandre Fifre ◽  
Catherine Malaplate‐Armand ◽  
Karine Lozac'h‐Pillot ◽  
...  
Keyword(s):  
Neuronal Apoptosis ◽  
Amyloid Β ◽  
Phospholipase A ◽  
Amyloid Β Peptide ◽  
Cytosolic Phospholipase ◽  
Phospholipase A 2

scholarly journals Cytosolic phospholipase A 2 protein as a novel therapeutic target for spinal cord injury

2014 ◽  
Vol 75 (5) ◽  
pp. 644-658 ◽  
Author(s):  
Nai‐Kui Liu ◽  
Ling‐Xiao Deng ◽  
Yi Ping Zhang ◽  
Qing‐Bo Lu ◽  
Xiao‐Fei Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Therapeutic Target ◽  
Phospholipase A ◽  
Cytosolic Phospholipase ◽  
Cord Injury ◽  
Novel Therapeutic ◽  
Phospholipase A 2

scholarly journals Inherited human group IVA cytosolic phospholipase A 2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation

2015 ◽  
Vol 29 (11) ◽  
pp. 4568-4578 ◽  
Author(s):  
Nicholas S. Kirkby ◽  
Daniel M. Reed ◽  
Matthew L. Edin ◽  
Francesca Rauzi ◽  
Stefania Mataragka ◽  
...  
Keyword(s):  
Phospholipase A ◽  
Human Group ◽  
Cytosolic Phospholipase ◽  
Group Iva ◽  
Phospholipase A 2

scholarly journals Cytosolic Phospholipase A 2 α Is Critical for Angiotensin II–Induced Hypertension and Associated Cardiovascular Pathophysiology

Hypertension ◽  
2015 ◽  
Vol 65 (4) ◽  
pp. 784-792 ◽  
Author(s):  
Nayaab S. Khan ◽  
Chi Young Song ◽  
Brett L. Jennings ◽  
Anne M. Estes ◽  
Xiao R. Fang ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Phospholipase A ◽  
Cytosolic Phospholipase ◽  
Induced Hypertension ◽  
Phospholipase A 2

Cardioprotective adaptation to chronic hypoxia stimulates the ROS-dependent/cytosolic phospholipase A 2 a pathway in rat heart

2017 ◽  
Vol 112 ◽  
pp. 157
Author(s):  
Marketa Hlavackova ◽  
Petra Micova ◽  
Klara Hahnova ◽  
Barbora Elsnicova ◽  
Anna Chytilova ◽  
...  
Keyword(s):  
Rat Heart ◽  
Chronic Hypoxia ◽  
Phospholipase A ◽  
Cytosolic Phospholipase ◽  
Phospholipase A 2
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