Advances in rationally designed dual inhibitors of HIV-1 reverse transcriptase and integrase

2016 ◽  
Vol 24 (21) ◽  
pp. 5007-5016 ◽  
Author(s):  
Shuang-Xi Gu ◽  
Ping Xue ◽  
Xiu-Lian Ju ◽  
Yuan-Yuan Zhu
Keyword(s):  
Reverse Transcriptase ◽  
Dual Inhibitors ◽  
Hiv 1

scholarly journals Structure–Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

2015 ◽  
Vol 58 (4) ◽  
pp. 1915-1928 ◽  
Author(s):  
Giuliana Cuzzucoli Crucitti ◽  
Mathieu Métifiot ◽  
Luca Pescatori ◽  
Antonella Messore ◽  
Valentina Noemi Madia ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Structure Activity Relationship ◽  
Ribonuclease H ◽  
Activity Relationship ◽  
Structure Activity ◽  
Dual Inhibitors ◽  
Relationship Of ◽  
Hiv 1

Fullerene derivatives as dual inhibitors of HIV-1 reverse transcriptase and protease

2021 ◽  
Vol 31 ◽  
pp. 127675
Author(s):  
Takumi Yasuno ◽  
Tomoyuki Ohe ◽  
Hiroki Kataoka ◽  
Kosho Hashimoto ◽  
Yumiko Ishikawa ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Fullerene Derivatives ◽  
Dual Inhibitors ◽  
Hiv 1

Design, Synthesis, and Biological Evaluation of 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 Reverse Transcriptase

ChemMedChem ◽  
2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Rita Meleddu ◽  
Valeria Cannas ◽  
Simona Distinto ◽  
Giorgia Sarais ◽  
Claudia Del Vecchio ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Dual Inhibitors ◽  
Synthesis And Biological Evaluation ◽  
Hiv 1

Identification of HIV-1 Reverse Transcriptase Dual Inhibitors by a Combined Shape-, 2D-Fingerprint- and Pharmacophore-based Virtual Screening Approach

2011 ◽  
Vol 90 (2) ◽  
pp. A31 ◽  
Author(s):  
Simona Distinto ◽  
Francesca Esposito ◽  
Johannes Kirchmair ◽  
Cristina M. Cardia ◽  
Elias Maccioni ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Reverse Transcriptase ◽  
Screening Approach ◽  
Dual Inhibitors ◽  
Hiv 1 ◽  
Virtual Screening Approach

(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase

2015 ◽  
Vol 93 ◽  
pp. 452-460 ◽  
Author(s):  
Rita Meleddu ◽  
Simona Distinto ◽  
Angela Corona ◽  
Giulia Bianco ◽  
Valeria Cannas ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Dual Inhibitors ◽  
Hiv 1

Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase

2017 ◽  
Vol 130 ◽  
pp. 248-260 ◽  
Author(s):  
Vijay P. Sonar ◽  
Angela Corona ◽  
Simona Distinto ◽  
Elias Maccioni ◽  
Rita Meleddu ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Natural Product ◽  
Caffeic Acid ◽  
Dual Inhibitors ◽  
Hiv 1
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