Novel synthesis of nicotinamide derivatives of cytotoxic properties

2006 ◽  
Vol 14 (13) ◽  
pp. 4466-4476 ◽  
Author(s):  
Adel S. Girgis ◽  
Hanaa M. Hosni ◽  
Flora F. Barsoum
ChemInform ◽  
2010 ◽  
Vol 29 (18) ◽  
pp. no-no
Author(s):  
R. A. BISSELL ◽  
N. BODEN ◽  
R. J. BUSHBY ◽  
C. W. G. FISHWICK ◽  
E. HOLLAND ◽  
...  

ChemInform ◽  
2004 ◽  
Vol 35 (42) ◽  
Author(s):  
Buchammagari Haritha ◽  
Valluru Krishna Reddy ◽  
Masaki Takahashi ◽  
Mitsuji Yamashita

1997 ◽  
Vol 62 (5) ◽  
pp. 809-815 ◽  
Author(s):  
Velimir Popsavin ◽  
Ostoja Beric ◽  
Mirjana Popsavin ◽  
János Csanádi ◽  
Stevan Lajšic ◽  
...  

The key chiral synthon in a novel synthesis of (-)-allo-muscarine from D-glucose has been prepared by three independent routes. The most efficient one includes a four-step conversion via the 4-O-benzoyl derivatives of starting 2,5-anhydro-3,5-di-O-methanesulfonyl-L-idose ethylene acetal (2a) into 2,5-anhydro-3,6-dideoxy-L-lyxo-hexose ethylene acetal (4b). The intermediate 4b was efficiently converted into the chiral synthon 2,5-anhydro-4-O-benzoyl-3,6-dideoxy-L-arabino-hexose (4c) by Mitsunobu reaction.


1972 ◽  
Vol 37 (10) ◽  
pp. 1532-1537 ◽  
Author(s):  
Daniel L. Klayman ◽  
Robert J. Shine ◽  
J. David. Bower

1992 ◽  
Vol 47 (11) ◽  
pp. 1628-1632 ◽  
Author(s):  
Ahmed Hafez Hussein El-Ghandour ◽  
Mohamed Kamal Ahmed Ibrahim ◽  
Ibrahim Saad Abdel-Hafiz ◽  
Mohamed Hilmy Elnagdi

A novel synthesis of derivatives of the title ring system by reacting methylpyrazolo[5,1-c]-1,2,4-triazin-6-carbonitriles (9) with sulphur and subsequent treatment of the resulting thienopyrazolotriazines with acetivated double bond system is described.


Sign in / Sign up

Export Citation Format

Share Document