Comparative structure–activity relationships of benztropine analogues at the dopamine transporter and histamine H1 receptors

Santosh S. Kulkarni; Theresa A. Kopajtic; Jonathan L. Katz; Amy Hauck Newman

doi:10.1016/j.bmc.2006.01.017

Comparative structure–activity relationships of benztropine analogues at the dopamine transporter and histamine H1 receptors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.01.017 ◽

2006 ◽

Vol 14 (11) ◽

pp. 3625-3634 ◽

Cited By ~ 8

Author(s):

Santosh S. Kulkarni ◽

Theresa A. Kopajtic ◽

Jonathan L. Katz ◽

Amy Hauck Newman

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Comparative Structure ◽

Histamine H1 Receptors

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Structure–activity relationships for substrate recognition by the human dopamine transporter

Biochemical Pharmacology ◽

10.1016/j.bcp.2003.09.013 ◽

2004 ◽

Vol 67 (2) ◽

pp. 293-302 ◽

Cited By ~ 14

Author(s):

Michael Appell ◽

Janet L. Berfield ◽

Lijuan C. Wang ◽

William J. Dunn ◽

Nianhang Chen ◽

...

Keyword(s):

Dopamine Transporter ◽

Substrate Recognition ◽

Structure Activity Relationships ◽

Structure Activity

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Dopamine Transporter Uptake Blockers: Structure-Activity Relationships

Neurotransmitter Transporters ◽

10.1385/0-89603-372-4:263 ◽

2003 ◽

pp. 263-296

Author(s):

F. Ivy Carroll ◽

Anita H. Lewin ◽

Michael J. Kuhar

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Uptake Blockers

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Dopamine-Transporter Uptake Blockers: Structure-Activity Relationships

Neurotransmitter Transporters ◽

10.1385/1-59259-158-2:381 ◽

2003 ◽

pp. 381-432 ◽

Cited By ~ 8

Author(s):

F. Ivy Carroll ◽

Anita H. Lewin ◽

S. Wayne Mascarella

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Uptake Blockers

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ChemInform Abstract: COMPARATIVE STRUCTURE-ACTIVITY RELATIONSHIPS OF ANTIFOLATE TRIAZINES INHIBITING MURINE TUMOR CELLS SENSITIVE AND RESISTANT TO METHOTREXATE

Chemischer Informationsdienst ◽

10.1002/chin.198432251 ◽

1984 ◽

Vol 15 (32) ◽

Author(s):

C. D. SELASSIE ◽

C. HANSCH ◽

T. A. KHWAJA ◽

C. B. DIAS ◽

S. PENTECOST

Keyword(s):

Tumor Cells ◽

Structure Activity Relationships ◽

Murine Tumor ◽

Structure Activity ◽

Comparative Structure ◽

Murine Tumor Cells

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Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogs at the dopamine transporter

Journal of Medicinal Chemistry ◽

10.1021/jm00084a001 ◽

1992 ◽

Vol 35 (6) ◽

pp. 969-981 ◽

Cited By ~ 190

Author(s):

F. Ivy Carroll ◽

Anita H. Lewin ◽

John W. Boja ◽

Michael J. Kuhar

Keyword(s):

Dopamine Transporter ◽

Biochemical Characterization ◽

Structure Activity Relationships ◽

Structure Activity

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Uptake of serotonin into rat platelets and synaptosomes: comparative structure-activity relationships, energetics and evaluation of the effects of acute and chronic nortriptyline administration

Brain Research Bulletin ◽

10.1016/0361-9230(86)90162-0 ◽

1986 ◽

Vol 17 (1) ◽

pp. 67-73 ◽

Cited By ~ 13

Author(s):

T.A. Slotkin ◽

W.L. Whitmore ◽

K.L. Dew ◽

C.D. Kilts

Keyword(s):

Structure Activity Relationships ◽

Structure Activity ◽

Comparative Structure ◽

Rat Platelets

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Discovery of a Novel Dopamine Transporter Inhibitor, 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketone, as a Potential Cocaine Antagonist through 3D-Database Pharmacophore Searching. Molecular Modeling, Structure−Activity Relationships, and Behavioral Pharmacological Studies

Journal of Medicinal Chemistry ◽

10.1021/jm990516x ◽

2000 ◽

Vol 43 (3) ◽

pp. 351-360 ◽

Cited By ~ 53

Author(s):

Shaomeng Wang ◽

Sukumar Sakamuri ◽

Istvan J. Enyedy ◽

Alan P. Kozikowski ◽

Olivier Deschaux ◽

...

Keyword(s):

Molecular Modeling ◽

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Pharmacological Studies ◽

3D Database

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Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112674 ◽

2020 ◽

Vol 208 ◽

pp. 112674 ◽

Cited By ~ 1

Author(s):

JoLynn B. Giancola ◽

Alessandro Bonifazi ◽

Jianjing Cao ◽

Therese Ku ◽

Alexandra J. Haraczy ◽

...

Keyword(s):

Dopamine Transporter ◽

Metabolic Stability ◽

Structure Activity Relationships ◽

Bioisosteric Replacement ◽

Structure Activity

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Three-Dimensional Quantitative Structure−Activity Relationships of Mazindol Analogues at the Dopamine Transporter

Journal of Medicinal Chemistry ◽

10.1021/jm0102093 ◽

2002 ◽

Vol 45 (19) ◽

pp. 4119-4127 ◽

Cited By ~ 17

Author(s):

Santosh S. Kulkarni ◽

Amy Hauck Newman ◽

William J. Houlihan

Keyword(s):

Dopamine Transporter ◽

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Molecular Modeling, Structure–Activity Relationships and Functional Antagonism Studies of 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketones as a Novel Class of Dopamine Transporter Inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(01)00090-6 ◽

2001 ◽

Vol 9 (7) ◽

pp. 1753-1764 ◽

Cited By ~ 16

Author(s):

Shaomeng Wang ◽

Sukumar Sakamuri ◽

Istvan J. Enyedy ◽

Alan P. Kozikowski ◽

Wahiduz A. Zaman ◽

...

Keyword(s):

Molecular Modeling ◽

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Functional Antagonism

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