Structure–activity relationships for substrate recognition by the human dopamine transporter

Michael Appell; Janet L. Berfield; Lijuan C. Wang; William J. Dunn; Nianhang Chen; Maarten E.A. Reith

doi:10.1016/j.bcp.2003.09.013

Structure–activity relationships for substrate recognition by the human dopamine transporter

Biochemical Pharmacology ◽

10.1016/j.bcp.2003.09.013 ◽

2004 ◽

Vol 67 (2) ◽

pp. 293-302 ◽

Cited By ~ 14

Author(s):

Michael Appell ◽

Janet L. Berfield ◽

Lijuan C. Wang ◽

William J. Dunn ◽

Nianhang Chen ◽

...

Keyword(s):

Dopamine Transporter ◽

Substrate Recognition ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Dopamine Transporter Uptake Blockers: Structure-Activity Relationships

Neurotransmitter Transporters ◽

10.1385/0-89603-372-4:263 ◽

2003 ◽

pp. 263-296

Author(s):

F. Ivy Carroll ◽

Anita H. Lewin ◽

Michael J. Kuhar

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Uptake Blockers

Download Full-text

Dopamine-Transporter Uptake Blockers: Structure-Activity Relationships

Neurotransmitter Transporters ◽

10.1385/1-59259-158-2:381 ◽

2003 ◽

pp. 381-432 ◽

Cited By ~ 8

Author(s):

F. Ivy Carroll ◽

Anita H. Lewin ◽

S. Wayne Mascarella

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Uptake Blockers

Download Full-text

Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogs at the dopamine transporter

Journal of Medicinal Chemistry ◽

10.1021/jm00084a001 ◽

1992 ◽

Vol 35 (6) ◽

pp. 969-981 ◽

Cited By ~ 190

Author(s):

F. Ivy Carroll ◽

Anita H. Lewin ◽

John W. Boja ◽

Michael J. Kuhar

Keyword(s):

Dopamine Transporter ◽

Biochemical Characterization ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Comparative structure–activity relationships of benztropine analogues at the dopamine transporter and histamine H1 receptors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.01.017 ◽

2006 ◽

Vol 14 (11) ◽

pp. 3625-3634 ◽

Cited By ~ 8

Author(s):

Santosh S. Kulkarni ◽

Theresa A. Kopajtic ◽

Jonathan L. Katz ◽

Amy Hauck Newman

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Comparative Structure ◽

Histamine H1 Receptors

Download Full-text

Discovery of a Novel Dopamine Transporter Inhibitor, 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketone, as a Potential Cocaine Antagonist through 3D-Database Pharmacophore Searching. Molecular Modeling, Structure−Activity Relationships, and Behavioral Pharmacological Studies

Journal of Medicinal Chemistry ◽

10.1021/jm990516x ◽

2000 ◽

Vol 43 (3) ◽

pp. 351-360 ◽

Cited By ~ 53

Author(s):

Shaomeng Wang ◽

Sukumar Sakamuri ◽

Istvan J. Enyedy ◽

Alan P. Kozikowski ◽

Olivier Deschaux ◽

...

Keyword(s):

Molecular Modeling ◽

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Pharmacological Studies ◽

3D Database

Download Full-text

Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112674 ◽

2020 ◽

Vol 208 ◽

pp. 112674 ◽

Cited By ~ 1

Author(s):

JoLynn B. Giancola ◽

Alessandro Bonifazi ◽

Jianjing Cao ◽

Therese Ku ◽

Alexandra J. Haraczy ◽

...

Keyword(s):

Dopamine Transporter ◽

Metabolic Stability ◽

Structure Activity Relationships ◽

Bioisosteric Replacement ◽

Structure Activity

Download Full-text

Three-Dimensional Quantitative Structure−Activity Relationships of Mazindol Analogues at the Dopamine Transporter

Journal of Medicinal Chemistry ◽

10.1021/jm0102093 ◽

2002 ◽

Vol 45 (19) ◽

pp. 4119-4127 ◽

Cited By ~ 17

Author(s):

Santosh S. Kulkarni ◽

Amy Hauck Newman ◽

William J. Houlihan

Keyword(s):

Dopamine Transporter ◽

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

Download Full-text

Molecular Modeling, Structure–Activity Relationships and Functional Antagonism Studies of 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketones as a Novel Class of Dopamine Transporter Inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(01)00090-6 ◽

2001 ◽

Vol 9 (7) ◽

pp. 1753-1764 ◽

Cited By ~ 16

Author(s):

Shaomeng Wang ◽

Sukumar Sakamuri ◽

Istvan J. Enyedy ◽

Alan P. Kozikowski ◽

Wahiduz A. Zaman ◽

...

Keyword(s):

Molecular Modeling ◽

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity ◽

Functional Antagonism

Download Full-text

Structure–Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic Stability

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.9b01188 ◽

2019 ◽

Vol 63 (5) ◽

pp. 2343-2357 ◽

Cited By ~ 6

Author(s):

Rachel D. Slack ◽

Therese C. Ku ◽

Jianjing Cao ◽

JoLynn B. Giancola ◽

Alessandro Bonifazi ◽

...

Keyword(s):

Dopamine Transporter ◽

Metabolic Stability ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Cytotoxicity of β-carbolines in dopamine transporter expressing cells: Structure–activity relationships

Biochemical Pharmacology ◽

10.1016/j.bcp.2007.06.046 ◽

2007 ◽

Vol 74 (7) ◽

pp. 1065-1077 ◽

Cited By ~ 16

Author(s):

Catrin Wernicke ◽

Yvonne Schott ◽

Christoph Enzensperger ◽

Gert Schulze ◽

Jochen Lehmann ◽

...

Keyword(s):

Dopamine Transporter ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text