scholarly journals Noninvasive imaging analysis of biological tissue associated with laser thermal injury

2017 ◽  
Vol 40 (2) ◽  
pp. 106-112 ◽  
Author(s):  
Cheng-Jen Chang ◽  
De-Yi Yu ◽  
Yen-Chang Hsiao ◽  
Kuang-Hua Ho
Keyword(s):  
Biological Tissue ◽  
Thermal Injury ◽  
Noninvasive Imaging ◽  
Imaging Analysis

scholarly journals Modeling of thermal injury produced by laser ablation of biological tissue

1993 ◽  
Author(s):  
Vasan Venugopalan ◽  
Norman S. Nishioka ◽  
B. B. Mikic
Keyword(s):  
Laser Ablation ◽  
Biological Tissue ◽  
Thermal Injury

The Effect of Laser Parameters on the Zone of Thermal Injury Produced by Laser Ablation of Biological Tissue

1994 ◽  
Vol 116 (1) ◽  
pp. 62-70 ◽  
Author(s):  
V. Venugopalan ◽  
N. S. Nishioka ◽  
B. B. Mikic´
Keyword(s):  
Laser Ablation ◽  
Pulse Duration ◽  
Biological Tissue ◽  
Thermal Injury ◽  
Thermal Damage ◽  
Optical Scattering ◽  
Published Data ◽  
Laser Parameters ◽  
Model Predictions ◽  
Key Parameter

A thermal model to predict the effect of laser parameters on the zone of thermal injury produced by laser ablation of biological tissue is presented. The model suggests that the Pe´cle`t number based on the optical penetration depth of laser radiation is the key parameter in determining the resulting zone of thermal injury. We show that the zone of thermal injury is minimized for Pe´cle`t numbers greater than one since the transport of energy via conduction beyond the ablation front is minimized. We also show that for Pe´cle`t numbers less than one, larger zones of thermal damage are unavoidable regardless of the laser pulse duration. The predictions of the model are compared with data available in the literature. Deviations between the model predictions and published data are discussed and the potential effects of the model assumptions, optical scattering, pyrolysis, temporal pulse shape, pulse duration, irradiance and pulse repetition rate are explored.

Advances in Microprobe Analysis Applied to Muscle, Nerve and Gland

1982 ◽  
Vol 40 ◽  
pp. 404-407
Author(s):  
T. E. Hutchinson ◽  
D. E. Johnson ◽  
A. C. Lee ◽  
E. Y. Wang
Keyword(s):  
Biological Tissue ◽  
Microprobe Analysis ◽  
Physiological State ◽  
External Environment ◽  
Physiological Relevance ◽  
Muscle Nerve ◽  
Technique Development

Microprobe analysis of biological tissue is now in the end phase of transition from instrumental and technique development to applications pertinent to questions of physiological relevance. The promise,implicit in early investigative efforts, is being fulfilled to an extent much greater than many had predicted. It would thus seem appropriate to briefly report studies exemplifying this, ∿. In general, the distributions of ions in tissue in a preselected physiological state produced by variations in the external environment is of importance in elucidating the mechanisms of exchange and regulation of these ions.

Complementary Z-Contrast Imaging and Digital Image Processing

1985 ◽  
Vol 43 ◽  
pp. 304-305
Author(s):  
K. N. Colonna ◽  
G. Oliphant
Keyword(s):  
Image Processing ◽  
Heavy Metal ◽  
Digital Image Processing ◽  
Digital Image ◽  
Biological Tissue ◽  
Biological Imaging ◽  
Tissue Preparation ◽  
Contrast Imaging ◽  
Imaging Tool ◽  
Z Contrast

Harmonious use of Z-contrast imaging and digital image processing as an analytical imaging tool was developed and demonstrated in studying the elemental constitution of human and maturing rabbit spermatozoa. Due to its analog origin (Fig. 1), the Z-contrast image offers information unique to the science of biological imaging. Despite the information and distinct advantages it offers, the potential of Z-contrast imaging is extremely limited without the application of techniques of digital image processing. For the first time in biological imaging, this study demonstrates the tremendous potential involved in the complementary use of Z-contrast imaging and digital image processing.Imaging in the Z-contrast mode is powerful for three distinct reasons, the first of which involves tissue preparation. It affords biologists the opportunity to visualize biological tissue without the use of heavy metal fixatives and stains. For years biologists have used heavy metal components to compensate for the limited electron scattering properties of biological tissue.

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