Sustainable lipid production from oleaginous fungus Syncephalastrum racemosum using synthetic and watermelon peel waste media

2020 ◽  
Vol 12 ◽  
pp. 100569 ◽  
Author(s):  
Amr Hosny Hashem ◽  
Waleed Bakry Suleiman ◽  
Gadallah Abu-elreesh ◽  
Amr Mohamed Shehabeldine ◽  
Ahmed Mohamed Aly Khalil
Keyword(s):  
Lipid Production ◽  
Syncephalastrum Racemosum ◽  
Oleaginous Fungus

Enhanced growth and lipid production in oleaginous fungus, Sarocladium kiliense ADH17: Study on fatty acid profiling and prediction of biodiesel properties

2019 ◽  
Vol 135 ◽  
pp. 10-20 ◽  
Author(s):  
Hoda Nouri ◽  
Hamid Moghimi ◽  
Mahzad Nikbakht Rad ◽  
Marjan Ostovar ◽  
Shima Sadat Farazandeh Mehr ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Lipid Production ◽  
Biodiesel Properties ◽  
Fatty Acid Profiling ◽  
Oleaginous Fungus ◽  
Sarocladium Kiliense

scholarly journals Enhancement of lipid productivity from a promising oleaginous fungus Aspergillus sp. strain EM2018 for biodiesel production: Optimization of culture conditions and identification

2020 ◽  
Vol 71 (3) ◽  
pp. 371
Author(s):  
E. M. Abdellah ◽  
T. H. Ali ◽  
D. A.M. Abdou ◽  
N. M. Hassanein ◽  
M. Fadel ◽  
...  
Keyword(s):  
Unsaturated Fatty Acids ◽  
Incubation Temperature ◽  
Inorganic Nitrogen ◽  
Lipid Production ◽  
Culture Conditions ◽  
Production Optimization ◽  
Biodiesel Production ◽  
Dry Cell Weight ◽  
Oleaginous Fungus ◽  
Optimization Of Culture Conditions

Oleaginous fungi have recently gained increasing attention among different microorganisms due to their ability for lipid production for the preparation of biofuel. In the present study, a locally isolated fungus E45, identified genetically as Aspergillus sp. strain EM2018, was found to produce 25.2% of the total lipids content of its dry cell weight (DCW). Optimization of culture conditions was performed and lipid accumula­tion increased by about 2.4 fold (from 25.2% to 60.1% of DCW) when the fungus was grown for seven days in the potato dextrose (50 g/L) liquid medium at pH 5.0, incubation temperature at 30 ºC and inoculum size of 2 × 106 spore/mL. Supplementation of the medium with yeast extract and NaNO3 at a concentration of 0.05% as organic and inorganic nitrogen sources, respectively, increased lipid production (53.3% lipid/dry biomass). Gas chromatography analysis of fungal lipids revealed the presence of saturated (mainly palmitic acid C16:0 (33%) and lignoceric acid C24:0 (15%)) and unsaturated fatty acids in different proportions (mainly linoleic acid C18:2 (24.4%), oleica cid C18:1 (14%) and arachidonic C20:4 (7.4%). These findings suggest this new oleaginous fungus as a promising feedstock for various industrial applications and for the preparation of biodiesel.

Untangling the Metabolic Reprogramming in Brain Cancer: Discovering Key Molecular Players Using Mass Spectrometry

2019 ◽  
Vol 19 (17) ◽  
pp. 1521-1534 ◽  
Author(s):  
Anatoly Sorokin ◽  
Vsevolod Shurkhay ◽  
Stanislav Pekov ◽  
Evgeny Zhvansky ◽  
Daniil Ivanov ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Brain Cancer ◽  
De Novo ◽  
Aerobic Glycolysis ◽  
Lipid Production ◽  
Dietary Fatty Acids ◽  
Metabolic Reprogramming ◽  
Detection Methods ◽  
Malignant Cells ◽  
Proliferating Cells

Cells metabolism alteration is the new hallmark of cancer, as well as an important method for carcinogenesis investigation. It is well known that the malignant cells switch to aerobic glycolysis pathway occurring also in healthy proliferating cells. Recently, it was shown that in malignant cells de novo synthesis of the intracellular fatty acid replaces dietary fatty acids which change the lipid composition of cancer cells noticeably. These alterations in energy metabolism and structural lipid production explain the high proliferation rate of malignant tissues. However, metabolic reprogramming affects not only lipid metabolism but many of the metabolic pathways in the cell. 2-hydroxyglutarate was considered as cancer cell biomarker and its presence is associated with oxidative stress influencing the mitochondria functions. Among the variety of metabolite detection methods, mass spectrometry stands out as the most effective method for simultaneous identification and quantification of the metabolites. As the metabolic reprogramming is tightly connected with epigenetics and signaling modifications, the evaluation of metabolite alterations in cells is a promising approach to investigate the carcinogenesis which is necessary for improving current diagnostic capabilities and therapeutic capabilities. In this paper, we overview recent studies on metabolic alteration and oncometabolites, especially concerning brain cancer and mass spectrometry approaches which are now in use for the investigation of the metabolic pathway.

Dynamic flux balance analysis of biomass and lipid production by Antarctic thraustochytrid Oblongichytrium sp. RT2316‐13

2020 ◽  
Vol 117 (10) ◽  
pp. 3006-3017 ◽  
Author(s):  
Carolina Shene ◽  
Paris Paredes ◽  
Liset Flores ◽  
Allison Leyton ◽  
Juan A. Asenjo ◽  
...  
Keyword(s):  
Flux Balance Analysis ◽  
Lipid Production ◽  
Dynamic Flux Balance Analysis ◽  
Flux Balance ◽  
Balance Analysis

scholarly journals Human crypt intestinal epithelial cells are capable of lipid production, apolipoprotein synthesis, and lipoprotein assembly

2000 ◽  
Vol 41 (1) ◽  
pp. 12-22 ◽  
Author(s):  
Emile Levy ◽  
Jean-François Beaulieu ◽  
Edgard Delvin ◽  
Ernest Seidman ◽  
Wagner Yotov ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Intestinal Epithelial Cells ◽  
Lipid Production ◽  
Intestinal Epithelial ◽  
Lipoprotein Assembly
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