Electrochemiluminescent immunosensing of prostate-specific antigen based on silver nanoparticles-doped Pb (II) metal-organic framework

2016 ◽  
Vol 79 ◽  
pp. 379-385 ◽  
Author(s):  
Hongmin Ma ◽  
Xiaojian Li ◽  
Tao Yan ◽  
Yan Li ◽  
Yong Zhang ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Prostate Specific Antigen ◽  
Metal Organic Framework ◽  
Specific Antigen ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Zn(II) Metal-organic Framework Nanoparticles: Synthesis, Characterization and Application as Optical Biosensor for Prostate-Specific Antigen

2021 ◽  
Author(s):  
Amal S. Basaleh ◽  
S. M. El-Sheikh
Keyword(s):  
Prostate Specific Antigen ◽  
Metal Organic Framework ◽  
Specific Antigen ◽  
Interaction Mechanism ◽  
Optical Biosensor ◽  
Human Beings ◽  
Vis Spectroscopy ◽  
Metal Organic ◽  
Ft Ir ◽  
Organic Framework

Abstract PSA, abbreviated of “Prostate-Specific Antigen” is widely used as a considered a significant cancer biomarker for diagnosing prostate cancer. Improvement of a fast, facile, and less cost with high accurate/sensitive/selective methodologies for the PSA determination is stock-still a challenge. In this work, we reported a simple biosensor based on a Zn(II) metal-organic framework nanoparticles (Zn-MOF-NPs) derived from reaction of zinc acetate with nano organic linker. The structure, morphology, and physicochemical properties of the prepared Zn(II)-MOF-NPs were definite using various spectroscopic and microanalytical tools as SEM-EDX, HR-TEM, XRD, XPS, elemental analysis, FT-IR, UV-vis spectroscopy, mass spectroscopy, thermogravimetric Analysis (DSC/TGA), and photoluminescence (PL). Obviously, the results revealed that the Zn(II)-MOF-NPs is chemical stable, highly selective and sensitive to PSA, without interferences with other common interfering analytes. The detection limit for PSA was 0.145 fg/mL, in a wide-linear range of concentrations (0.1 fg/mL-20 pg/mL), with a correlation coefficient 0.983. The Zn(II)-MOF-NPs was successfully used as an up-and-coming biosensor for PSA-monitoring and quantification in biological real samples (plasma/whole blood/serum) at clinical target concentration levels. Moreover, the present approach will help the human-beings from the hazard’s prostatic cancer through early discovery and diagnosis process via the detection of PSA at low limits of concentrations. Meantime, the interaction mechanism between the Zn(II)-MOF-NPs and PSA was well studied and investigated.

Preparation of Well-Dispersed Nanosilver in MIL-101(Cr) Using Double-Solvent Radiation Method for Catalysis

NANO ◽  
2018 ◽  
Vol 13 (12) ◽  
pp. 1850145 ◽  
Author(s):  
Shuquan Chang ◽  
Chengcheng Liu ◽  
Heliang Fu ◽  
Zheng Li ◽  
Xian Wu ◽  
...  
Keyword(s):  
Particle Size ◽  
Silver Nanoparticles ◽  
Porous Materials ◽  
Chemical Treatment ◽  
Metal Organic Framework ◽  
Catalytic Performance ◽  
Radiation Method ◽  
Metal Organic ◽  
Excellent Catalytic Performance ◽  
Organic Framework

In this study, a double-solvent radiation method is proposed to prepare silver nanoparticles in the pores of metal-organic framework MIL-101(Cr). The results reveal that well-dispersed silver nanoparticles with a diameter of about 2[Formula: see text]nm were successfully fabricated in the cages of monodisperse octahedral MIL-101(Cr) with a particle size of about 400[Formula: see text]nm. The structure of MIL-101(Cr) was not destroyed during the chemical treatment and irradiation. The resulting Ag/MIL-101 exhibits excellent catalytic performance for the reduction of 4-nitrophenol. This method can be extended to prepare other single or bimetallic components inside porous materials.

A novel electrochemical sensor of tryptophan based on silver nanoparticles/metal–organic framework composite modified glassy carbon electrode

RSC Advances ◽  
2016 ◽  
Vol 6 (17) ◽  
pp. 13742-13748 ◽  
Author(s):  
Zhewei Peng ◽  
Zhongwei Jiang ◽  
Xin Huang ◽  
Yuanfang Li
Keyword(s):  
Silver Nanoparticles ◽  
Electrochemical Sensor ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Metal Organic Framework ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Metal Organic ◽  
Organic Framework

A familiar metal–organic framework MIL-101(Fe) and silver nanoparticles composite acted as a novel electrode modified material for the detection of tryptophan.

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