Chemically imaging living cells by scanning electrochemical microscopy

2006 ◽  
Vol 22 (4) ◽  
pp. 461-472 ◽  
Author(s):  
Allen J. Bard ◽  
Xiao Li ◽  
Wei Zhan
Keyword(s):  
Scanning Electrochemical Microscopy ◽  
Living Cells ◽  
Electrochemical Microscopy

Scanning electrochemical microscopy of living cells

2001 ◽  
Vol 500 (1-2) ◽  
pp. 590-597 ◽  
Author(s):  
Biao Liu ◽  
Wei Cheng ◽  
Susan A. Rotenberg ◽  
Michael V. Mirkin
Keyword(s):  
Scanning Electrochemical Microscopy ◽  
Living Cells ◽  
Electrochemical Microscopy

scholarly journals Monitoring Activity of Living Cells Entrapped in a Membrane-Sealed Microcapillary with Scanning Electrochemical Microscopy

2000 ◽  
Vol 68 (11) ◽  
pp. 890-892 ◽  
Author(s):  
Hitoshi SHIKU ◽  
Takuo SHIRAISHI ◽  
Hiroaki OHYA ◽  
Tomokazu MATSUE ◽  
Hiroyuki ABE ◽  
...  
Keyword(s):  
Scanning Electrochemical Microscopy ◽  
Living Cells ◽  
Monitoring Activity ◽  
Electrochemical Microscopy

scholarly journals Recent Advances in Scanning Electrochemical Microscopy for Biological Applications

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1389 ◽  
Author(s):  
Luyao Huang ◽  
Ziyu Li ◽  
Yuntian Lou ◽  
Fahe Cao ◽  
Dawei Zhang ◽  
...  
Keyword(s):  
Physiological Activity ◽  
Chemical Species ◽  
Scanning Electrochemical Microscopy ◽  
Living Cells ◽  
Basic Principles ◽  
Specific Chemical ◽  
Microscopy Technique ◽  
Biological Studies ◽  
Computer Controlled ◽  
Electrochemical Microscopy

Scanning electrochemical microscopy (SECM) is a chemical microscopy technique with high spatial resolution for imaging sample topography and mapping specific chemical species in liquid environments. With the development of smaller, more sensitive ultramicroelectrodes (UMEs) and more precise computer-controlled measurements, SECM has been widely used to study biological systems over the past three decades. Recent methodological breakthroughs have popularized SECM as a tool for investigating molecular-level chemical reactions. The most common applications include monitoring and analyzing the biological processes associated with enzymatic activity and DNA, and the physiological activity of living cells and other microorganisms. The present article first introduces the basic principles of SECM, followed by an updated review of the applications of SECM in biological studies on enzymes, DNA, proteins, and living cells. Particularly, the potential of SECM for investigating bacterial and biofilm activities is discussed.

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