A novel method to construct a third-generation biosensor: self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres

2004 ◽  
Vol 19 (9) ◽  
pp. 1117-1120 ◽  
Author(s):  
Shiyi Xu ◽  
Xiaozu Han
Keyword(s):  
Gold Nanoparticles ◽  
Acrylic Acid ◽  
Third Generation ◽  
Self Assembling ◽  
Novel Method

A Method to Construct a Third-Generation Horseradish Peroxidase Biosensor:  Self-Assembling Gold Nanoparticles to Three-Dimensional Sol−Gel Network

2002 ◽  
Vol 74 (9) ◽  
pp. 2217-2223 ◽  
Author(s):  
Jianbo Jia ◽  
Bingquan Wang ◽  
Aiguo Wu ◽  
Guangjin Cheng ◽  
Zhuang Li ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Horseradish Peroxidase ◽  
Sol Gel ◽  
Three Dimensional ◽  
Third Generation ◽  
Self Assembling ◽  
Gel Network

Self-assembling of gold nanoparticles in one, two, and three dimensions

2000 ◽  
Vol 71 (3) ◽  
pp. 237-243 ◽  
Author(s):  
C. Gutiérrez-Wing ◽  
P. Santiago ◽  
J.A. Ascencio ◽  
A. Camacho ◽  
M. José-Yacamán
Keyword(s):  
Gold Nanoparticles ◽  
Three Dimensions ◽  
Self Assembling

scholarly journals SYNTHESIS AND STABILITY OF RESVERATROL-CONJUGATED GOLD NANOPARTICLES MODIFIED WITH POLYETHYLENE GLYCOL

2020 ◽  
pp. 230-236
Author(s):  
RADITYA ISWANDANA ◽  
RICHA NURSELVIANA ◽  
SUTRIYO SUTRIYO
Keyword(s):  
Particle Size ◽  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Zeta Potential ◽  
High Performance ◽  
Entrapment Efficiency ◽  
Test Results ◽  
Novel Method ◽  
The Stability ◽  
Phosphate Buffered Saline

Objective: Gold nanoparticles (AuNPs) are highly useful for drug delivery, but their application is limited by their stability as they readily aggregate.This issue can be prevented by adding a stabilizing agent such as resveratrol (RSV), which is a polyphenol derived from plants, that is used to preventcancer. Therefore, we propose a novel method to prepare stable RSV-conjugated nanoparticles modified with polyethylene glycol (RSV-AuNP-PEG).Methods: In the first step, the Turkevich method was used to synthesize the AuNPs. Then, PEG was added as stabilizer agent and conjugated with RSV.The synthesized conjugates were characterized using ultraviolet-visible spectrophotometry, Fourier transform infrared spectroscopy, particle sizeanalysis, and high-performance liquid chromatography.Results: The obtained RSV-AuNP-PEG had a particle size of 83.93 nm with a polydispersity index (PDI) of 0.562 and formed a translucent purple-redfluid in solution. The zeta potential was −22.9 mV, and the highest entrapment efficiency was 75.86±0.66%. For comparison, the RSV-AuNP solutionwas purple and turbid, the particle size was 51.97 nm with a PDI of 0.694, and the zeta potential was −24.6 mV. The stability test results showed thatthe storage stability of RSV-AuNP-PEG was better than that of AuNP-RSV. Further, the RSV-AuNP-PEG was shown to be most stable in 2% bovine serumalbumin (BSA) while the AuNP-RSV was most stable in 2% BSA in phosphate-buffered saline pH 7.4.Conclusion: These results show that modification of RSV-conjugated AuNPs with PEG effectively prevents their aggregation in storage, but only incertain mediums.

Layer-by-layer self-assembly of polydopamine/gold nanoparticle/thiol coating as the stationary phase for open tubular capillary electrochromatography

2015 ◽  
Vol 7 (19) ◽  
pp. 8227-8234 ◽  
Author(s):  
Xiu-Ju Li ◽  
Qi-Feng Fu ◽  
Qi-Hui Zhang ◽  
Xue-Mei Jiang ◽  
Feng-Qing Yang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Stationary Phase ◽  
Gold Nanoparticle ◽  
Self Assembly ◽  
Capillary Electrochromatography ◽  
Phase Ratio ◽  
Layer By Layer ◽  
Novel Method ◽  
First Time ◽  
High Phase

A novel method for the preparation of permanent coating columns with a high phase ratio based on the multiple properties of PDA and LBL self-assembly of polydopamine/gold nanoparticles/thiols has been developed for the first time.

Photocatalytic Nanostructured Self-Assembled Poly(allylamine hydrochloride)/Poly(acrylic acid) Polyelectrolyte Films Containing Titanium Dioxide–Gold Nanoparticles for Hydrogen Generation

2013 ◽  
Vol 117 (44) ◽  
pp. 23235-23243 ◽  
Author(s):  
Nicolle Dal’Acqua ◽  
Francine Ramos Scheffer ◽  
Rosiana Boniatti ◽  
Barbara Virgínia Mendonça da Silva ◽  
Janaina Viana de Melo ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Titanium Dioxide ◽  
Acrylic Acid ◽  
Hydrogen Generation ◽  
Allylamine Hydrochloride ◽  
Self Assembled ◽  
Poly Acrylic Acid

scholarly journals Sensitive detection of methylated DNA and methyltransferase activity based on the lighting up of FAM-labeled DNA quenched fluorescence by gold nanoparticles

RSC Advances ◽  
2019 ◽  
Vol 9 (21) ◽  
pp. 12063-12069 ◽  
Author(s):  
Mohammad Ali Karimi ◽  
Mehdi Dadmehr ◽  
Morteza Hosseini ◽  
Behnaz Korouzhdehi ◽  
Fatemeh Oroojalian
Keyword(s):  
Dna Methylation ◽  
Gold Nanoparticles ◽  
Sensitive Detection ◽  
Fluorescence Recovery ◽  
Methyltransferase Activity ◽  
Au Nps ◽  
Methylated Dna ◽  
Novel Method

A novel method for detection of DNA methylation based on fluorescence recovery of FAM labeled DNA/Au NPs was introduced.

Preparation of Poly(Acrylic Acid) Crosslinked-Gold Nanoparticles for Colorimetric Detection of Analytes

2019 ◽  
Vol 950 ◽  
pp. 138-143
Author(s):  
Erindyah Retno Wikantyasning ◽  
Mutmainnah Mutmainnah ◽  
Ghiyats Ramadhan ◽  
Zakky Cholisoh ◽  
Muhammad Da'i
Keyword(s):  
Gold Nanoparticles ◽  
Herbal Medicine ◽  
Acrylic Acid ◽  
Color Change ◽  
Colorimetric Detection ◽  
Ph Responsive ◽  
Herbal Medicine Product ◽  
Responsive Polymer ◽  
Medicine Product ◽  
Poly Acrylic Acid

The aims of this study are to synthesize and characterize gold nanoparticles (AuNPs) crosslinked by pH-responsive polymer poly (acrylic acid) (PAA) and its application for detection of some analytes in herbal medicine product. In this study, a pH-responsive polymer, poly (acrylic acid) was prepared by the reversible addition-fragmentation chain transfer (RAFT) polymerization method. The polymer was then cross-linked by gold nanoparticles, which was synthesized by the Turkevich method. The response of the AuNPs-crosslinked PAA was observed by the color change from red to blue at a specific pH (4-5) and was characterized by TEM. The reversible color change was resulted from aggregation and disaggregation of the AuNPs due to the shrinking and swelling of the polymer when different pH was introduced as a stimulant. This sensor has the capability of recognizing analytes such as aspirin and tolbutamide added in the herbal medicine product at the concentration of 0.04-0.05 M.

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