scholarly journals “Fibrous nests” in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome

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Sihem Mebarki ◽  
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Marie Sicard ◽  
Elise Lavergne ◽  
...  
Hepatology ◽  
2016 ◽  
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Jing Xu ◽  
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Ru-Hai Zou ◽  
Keng Chen ◽  
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LONG-ZI LIU ◽  
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In an early liver damage mouse model, Smad7 induced compensatory hepatocyte proliferation. High Smad7 expression was associated with better prognosis in human hepatocellular carcinoma, especially in distinct subgroups. A YB-1 dependent mechanism was involved in Smad7 up-regulation in HCC.


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Kerstin Fischer ◽  
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Ariane Aigelsreiter ◽  
Johannes Haybaeck ◽  
Silvia Schauer ◽  
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Dandan Zhang ◽  
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