Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

Yakun Chen; Yong Tang; Changxiong Guo; Jiuhui Wang; Debasish Boral; Daotai Nie

doi:10.1016/j.bcp.2012.01.030

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

Biochemical Pharmacology ◽

10.1016/j.bcp.2012.01.030 ◽

2012 ◽

Vol 83 (8) ◽

pp. 1112-1126 ◽

Cited By ~ 127

Author(s):

Yakun Chen ◽

Yong Tang ◽

Changxiong Guo ◽

Jiuhui Wang ◽

Debasish Boral ◽

...

Keyword(s):

Multidrug Resistance ◽

Nuclear Receptors ◽

Drug Transporters ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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Nuclear Receptors and the Regulation of Drug-Metabolizing Enzymes and Drug Transporters: Implications for Interindividual Variability in Response to Drugs

The Journal of Clinical Pharmacology ◽

10.1177/0091270007299930 ◽

2007 ◽

Vol 47 (5) ◽

pp. 566-578 ◽

Cited By ~ 264

Author(s):

Bradley L. Urquhart ◽

Rommel G. Tirona ◽

Richard B. Kim

Keyword(s):

Nuclear Receptors ◽

Interindividual Variability ◽

Drug Transporters ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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Expression of clinically relevant drug‐metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra‐subject analysis

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/bcpt.13137 ◽

2018 ◽

Vol 124 (3) ◽

pp. 245-255 ◽

Cited By ~ 10

Author(s):

Anja Fritz ◽

Diana Busch ◽

Joanna Lapczuk ◽

Marek Ostrowski ◽

Marek Drozdzik ◽

...

Keyword(s):

Nuclear Receptors ◽

Drug Transporters ◽

Drug Metabolizing Enzymes ◽

Human Intestine ◽

Metabolizing Enzymes ◽

Subject Analysis

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Genetic Polymorphism of Drug‐Metabolizing Enzymes and Drug Transporters in Drug Toxicity

Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity ◽

10.1002/9781119171003.ch5 ◽

2021 ◽

pp. 139-165

Author(s):

Ann K. Daly

Keyword(s):

Genetic Polymorphism ◽

Drug Toxicity ◽

Drug Transporters ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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Regulation of brain drug metabolizing enzymes and transporters by nuclear receptors

Drug Metabolism Reviews ◽

10.1080/03602532.2018.1554673 ◽

2018 ◽

Vol 50 (4) ◽

pp. 407-414 ◽

Cited By ~ 5

Author(s):

Dan Xu ◽

Songqiang Huang ◽

Hui Wang ◽

Wen Xie

Keyword(s):

Nuclear Receptors ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells

Archives of Toxicology ◽

10.1007/s00204-020-02706-5 ◽

2020 ◽

Vol 94 (5) ◽

pp. 1637-1653 ◽

Cited By ~ 3

Author(s):

Dongying Li ◽

Leihong Wu ◽

Bridgett Knox ◽

Si Chen ◽

William H. Tolleson ◽

...

Keyword(s):

Nuclear Receptors ◽

Long Noncoding Rna ◽

Human Liver ◽

Noncoding Rna ◽

Liver Cells ◽

Molecular Network ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes ◽

Human Liver Cells

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Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters

FEBS Journal ◽

10.1111/febs.15116 ◽

2019 ◽

Vol 287 (7) ◽

pp. 1306-1322 ◽

Cited By ~ 8

Author(s):

William M. Atkins

Keyword(s):

Drug Transporters ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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MicroRNAs as regulators of drug transporters, drug-metabolizing enzymes, and tight junctions: Implication for intestinal barrier function

Pharmacology & Therapeutics ◽

10.1016/j.pharmthera.2014.03.002 ◽

2014 ◽

Vol 143 (2) ◽

pp. 217-224 ◽

Cited By ~ 30

Author(s):

Kenji Ikemura ◽

Takuya Iwamoto ◽

Masahiro Okuda

Keyword(s):

Tight Junctions ◽

Barrier Function ◽

Drug Transporters ◽

Intestinal Barrier ◽

Intestinal Barrier Function ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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Long noncoding RNA LINC00844‐mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in HepaRG cells

The FASEB Journal ◽

10.1096/fasebj.2020.34.s1.02615 ◽

2020 ◽

Vol 34 (S1) ◽

pp. 1-1

Author(s):

Baitang Ning ◽

Dongying Li ◽

Leihong Wu ◽

Bridgett Knox ◽

Si Chen ◽

...

Keyword(s):

Nuclear Receptors ◽

Long Noncoding Rna ◽

Noncoding Rna ◽

Molecular Network ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes ◽

Heparg Cells

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Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchiceine: Focus on PXR, CAR, and GR in primary human hepatocytes

Cell Biology and Toxicology ◽

10.1007/s10565-006-9001-y ◽

2006 ◽

Vol 23 (2) ◽

pp. 141-141

Author(s):

Z. Dvořák ◽

P. Maurel ◽

M.-J. Vilarem ◽

J. Ulrichová ◽

M. Modrianský

Keyword(s):

Nuclear Receptors ◽

Human Hepatocytes ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes ◽

Primary Human Hepatocytes

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Genotype Frequencies of Selected Drug Metabolizing Enzymes and ABC Drug Transporters among Breast Cancer Patients on FAC Chemotherapy

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/j.1742-7843.2009.00531.x ◽

2010 ◽

Vol 107 (1) ◽

pp. 570-576 ◽

Cited By ~ 14

Author(s):

Nasir Ali Afsar ◽

Sierk Haenisch ◽

Ahmed Mateen ◽

Ahmed Usman ◽

Mike Ufer ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Drug Transporters ◽

Drug Metabolizing Enzymes ◽

Breast Cancer Patients ◽

Metabolizing Enzymes ◽

Genotype Frequencies ◽

Fac Chemotherapy

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