scholarly journals Role of insular cortex D1 and D2 dopamine receptors in nicotine self-administration in rats

2013 ◽  
Vol 256 ◽  
pp. 273-278 ◽  
Author(s):  
Munir G. Kutlu ◽  
Dennis Burke ◽  
Susan Slade ◽  
Brandon J. Hall ◽  
Jed E. Rose ◽  
...  
Keyword(s):  
Dopamine Receptors ◽  
Insular Cortex ◽  
Self Administration ◽  
D2 Dopamine Receptors

Role of ventral pallidal D2 dopamine receptors in the consolidation of spatial memory

2016 ◽  
Vol 313 ◽  
pp. 1-9 ◽  
Author(s):  
László Péczely ◽  
Tamás Ollmann ◽  
Kristóf László ◽  
Anita Kovács ◽  
Rita Gálosi ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Dopamine Receptors ◽  
D2 Dopamine Receptors

scholarly journals The role of D2 dopamine receptors in oxytocin induced place preference and anxiolytic effect

2020 ◽  
Vol 124 ◽  
pp. 104777
Author(s):  
K. László ◽  
L. Péczely ◽  
F. Géczi ◽  
A. Kovács ◽  
O. Zagoracz ◽  
...  
Keyword(s):  
Dopamine Receptors ◽  
Anxiolytic Effect ◽  
Place Preference ◽  
D2 Dopamine Receptors

scholarly journals The potential role of D2 dopamine receptors as a target in the management of neuroendocrine tumors

2008 ◽  
Vol 7 (12) ◽  
pp. 1979-1981
Author(s):  
Antonio Ribeiro-Oliveira Jr. ◽  
Marta Korbonits ◽  
Ashley B. Grossman
Keyword(s):  
Dopamine Receptors ◽  
Neuroendocrine Tumors ◽  
Potential Role ◽  
D2 Dopamine Receptors

Role of D2 dopamine receptors of the ventral pallidum in inhibitory avoidance learning

2017 ◽  
Vol 321 ◽  
pp. 99-105 ◽  
Author(s):  
László Lénárd ◽  
Tamás Ollmann ◽  
Kristóf László ◽  
Anita Kovács ◽  
Rita Gálosi ◽  
...  
Keyword(s):  
Dopamine Receptors ◽  
Avoidance Learning ◽  
Inhibitory Avoidance ◽  
Ventral Pallidum ◽  
D2 Dopamine Receptors ◽  
Inhibitory Avoidance Learning

scholarly journals Dopamine modulates visual threat processing in the superior colliculus via D2 receptors

2021 ◽  
Author(s):  
Quentin Montardy ◽  
Zheng Zhou ◽  
Lei Li ◽  
Qingning Yang ◽  
Zhuogui Lei ◽  
...  
Keyword(s):  
Superior Colliculus ◽  
Dopamine Receptors ◽  
Defensive Behavior ◽  
D2 Receptors ◽  
Receptor System ◽  
D2 Dopamine Receptors ◽  
Visuomotor Integration ◽  
Defensive Responses ◽  
Defensive Behaviors

AbstractDopamine (DA) system is intriguing in the aspect that distinct, typically opposing physiological functions are mediated by D1 dopamine receptors (Drd1) and D2 dopamine receptors (Drd2). Both Drd1+ and Drd2+ neurons were identified in superior colliculus (SC), a visuomotor integration center known for its role in defensive behaviors to visual threats. We hypothesized that Drd1+ and Drd2+ neurons in the SC may play a role in promoting instinctive defensive responses.Optogenetic activation of Drd2+ neurons, but not Drd1+ neurons, in the SC triggered strong defensive behaviors. Chemogenetic inhibition of SC Drd2+ neurons decreased looming-induced defensive behavior, suggesting involvement of SC Drd2+ neurons in defensive responses. To further confirm this functional role of Drd2 receptors, pretreatment with the Drd2+ agonist quinpirole in the SC impaired looming-evoked defensive responses, suggesting an essential role of Drd2 receptors in the regulation of innate defensive behavior. Inputs and outputs of SC Drd2+ neurons were investigated using viral tracing: SC Drd2+ neurons mainly receive moderate inputs from the Locus Coeruleus (LC), whilst we did not find any incoming projections from other dopaminergic structures. Our results suggest a sophisticated regulatory role of DA and its receptor system in innate defensive behavior.

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