Role of enhanced noradrenergic transmission within the ventral bed nucleus of the stria terminalis in visceral pain-induced aversion in rats

2009 ◽  
Vol 197 (2) ◽  
pp. 279-283 ◽  
Author(s):  
Satoshi Deyama ◽  
Takahiro Katayama ◽  
Naoto Kondoh ◽  
Takayuki Nakagawa ◽  
Shuji Kaneko ◽  
...  
Keyword(s):  
Visceral Pain ◽  
Stria Terminalis ◽  
Bed Nucleus ◽  
Noradrenergic Transmission

Mo1100 Stress-Induced Colonic Hypersensitivity: the Role of the Bed Nucleus of the Stria Terminalis

2012 ◽  
Vol 142 (5) ◽  
pp. S-595
Author(s):  
Lee Tran ◽  
Beverley Greenwood-Van Meerveld
Keyword(s):  
Stria Terminalis ◽  
Bed Nucleus

scholarly journals Threat imminence dictates the role of the bed nucleus of the stria terminalis in contextual fear

2019 ◽  
Author(s):  
Travis D. Goode ◽  
Gillian M. Acca ◽  
Stephen Maren
Keyword(s):  
Unconditioned Stimulus ◽  
Fear Conditioning ◽  
Stria Terminalis ◽  
Conditioning Procedure ◽  
Conditioned Stimuli ◽  
Reversible Inactivation ◽  
Bed Nucleus ◽  
Contextual Fear ◽  
Context Dependent

ABSTRACTPrevious work indicates that the bed nucleus of the stria terminalis (BNST) is involved in defensive freezing to unpredictable Pavlovian conditioned stimuli (Goode et al., 2019). Here we show that the BNST mediates freezing to contexts paired with remote (unpredictable), but not imminent (predictable), footshock. Rats underwent a fear conditioning procedure in which a single footshock unconditioned stimulus (US) was delivered either 1 (imminent) or 9 minutes (remote) after placement in the context; each rat received a total of four conditioning trials over two days. Contexts associated with either imminent or remote USs produced distinct patterns of freezing and shock-induced activity but freezing in each case was context-dependent. Reversible inactivation of the BNST reduced the expression of contextual freezing in the context paired with remote, but not imminent, footshock. Implications of these data are discussed in light of recent conceptualizations of BNST function, as well as for anxiety behaviors.

The Role of the Bed Nucleus of the Stria Terminalis in Stress-Induced Inhibition of Pulsatile Luteinising Hormone Secretion in the Female Rat

2010 ◽  
Vol 23 (1) ◽  
pp. 3-11 ◽  
Author(s):  
X. F. Li ◽  
Y. S. Lin ◽  
J. S. Kinsey-Jones ◽  
S. R. Milligan ◽  
S. L. Lightman ◽  
...  
Keyword(s):  
Luteinising Hormone ◽  
Hormone Secretion ◽  
Stria Terminalis ◽  
Female Rat ◽  
Bed Nucleus

scholarly journals Role of the bed nucleus of the stria terminalis in the acquisition of contextual fear at long or short context-shock intervals.

2015 ◽  
Vol 129 (5) ◽  
pp. 673-678 ◽  
Author(s):  
Sayamwong E. Hammack ◽  
Travis P. Todd ◽  
Margaret Kocho-Schellenberg ◽  
Mark E. Bouton
Keyword(s):  
Stria Terminalis ◽  
Bed Nucleus ◽  
Contextual Fear

Modulation by arginine vasopressin of glutamate excitation in the ventral septal area of the rat brain

1987 ◽  
Vol 65 (1) ◽  
pp. 30-35 ◽  
Author(s):  
J. E. Disturnal ◽  
W. L. Veale ◽  
Q. J. Pittman
Keyword(s):  
Rat Brain ◽  
Paraventricular Nucleus ◽  
Septal Area ◽  
Inhibitory Input ◽  
Stria Terminalis ◽  
Evoked Responses ◽  
Bed Nucleus ◽  
Septal Neurons ◽  
Stimulation Of

Arginine vasopresin is hypothesized to act as a neurotransmitter or neuromodulator in the ventral septal area of the rat brain. To examine this role of vasopressin further, it was applied by microiontophoresis or micropressure from multiple-barrelled micropipettes onto spontaneously active or glutamate-activated neurons. Applied in this manner, vasopressin reduced glutamate-evoked excitation in 32 of the 47 cells studied. Further, micropressure application of the vasopressin antagonist d(CH2)5Tyr(Me)AVP reversed the vasopressin effects. In contrast, administration of vasopressin had no effect on excitations evoked by acetylcholine iontophoresis or on the spontaneous activity of the majority of the ventral septal neurons studied. These observations suggest that vasopressin may be acting on a V1-like receptor on specific neurons in the ventral septal area as a modulator of glutamate actions. Evoked responses were also obtained in the same population of ventral septal cells following stimulation of a variety of limbic areas. Inhibitory input onto most of the vasopressin responsive neurons studied was obtained following electrical stimulation of the paraventricular nucleus and bed nucleus of the stria terminalis, two cell groupings that are potential sources of vasopressin to the ventral septal area. Thus, the similarity in action of exogenously applied vasopressin and the evoked responses following paraventricular nucleus and bed nucleus stimulation suggests that vasopressin may be a neurotransmitter in this pathway.

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