scholarly journals Sex and Body Mass Index but Not CXCL12 801 G/A Polymorphism Determine the Efficacy of Hematopoietic Cell Mobilization: A Study in Healthy Volunteer Donors

2013 ◽  
Vol 19 (10) ◽  
pp. 1517-1521 ◽  
Author(s):  
Juliane Lenk ◽  
Martin Bornhauser ◽  
Michael Kramer ◽  
Kristina Hölig ◽  
Kirsten Poppe-Thiede ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Healthy Volunteer ◽  
Body Mass ◽  
Hematopoietic Cell ◽  
Cell Mobilization

scholarly journals Pediatric hematopoietic cell transplantation: Longitudinal trends in body mass index and outcomes

2020 ◽  
Vol 24 (7) ◽  
Author(s):  
Brian Norman Dang ◽  
Holly Wilhalme ◽  
James Ch'ng ◽  
Satiro De Oliveira ◽  
LaVette Bowles ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cell Transplantation ◽  
Body Mass ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell

Predictors of Oral Mucositis in Patients Receiving Hematopoietic Cell Transplants for Chronic Myelogenous Leukemia

2004 ◽  
Vol 22 (7) ◽  
pp. 1268-1275 ◽  
Author(s):  
Kim Robien ◽  
Mark M. Schubert ◽  
Barbara Bruemmer ◽  
Michele E. Lloid ◽  
John D. Potter ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Chronic Myelogenous Leukemia ◽  
Body Mass ◽  
Oral Mucositis ◽  
Methylenetetrahydrofolate Reductase ◽  
Hematopoietic Cell ◽  
Myelogenous Leukemia ◽  
Multivitamin Supplementation ◽  
Supplement Use ◽  
Conditioning Regimens

PurposeOral mucositis is a nearly universal and often severe complication following hematopoietic cell transplantation (HCT). The objective of this study was to evaluate factors predicting oral mucositis severity among 133 patients undergoing allogeneic HCT for chronic myelogenous leukemia.Patients and MethodsAll patients were transplanted between 1992 and 1999, were ≥ 18 years of age, received either cyclophosphamide/total-body irradiation (TBI) or busulfan/cyclophosphamide conditioning regimens, and received four doses of methotrexate for graft-versus-host disease prophylaxis post-transplant. Oral mucositis was measured by a trained examiner every 2 to 3 days using the Oral Mucositis Index (OMI). Multiple linear regression analysis was used to identify predictors of mean OMI during days 6 to 12, 1 to 18, and the maximum OMI score between days 1 to 18.ResultsTBI containing conditioning regimens, body mass index ≥ 25, and methylenetetrahydrofolate reductase 677 TT genotype were found to be predictive of higher mean OMI scores (P < .05). Pretransplant multivitamin supplement use was associated with lower mean OMI scores compared to those who did not use supplements. Smoking status, race, pretransplant treatment with interferon-alfa or hydroxyurea, and patient/donor ABO compatibility were not associated with mean OMI scores.ConclusionPatients who are scheduled to receive conditioning regimens containing TBI, have a pretransplant body mass index ≥ 25, or carry the methylenetetrahydrofolate reductase 677 TT genotype should be considered at greater risk of developing oral mucositis following HCT. Future studies should investigate whether multivitamin supplementation before HCT could reduce mucositis severity.

scholarly journals Donor body mass index does not predict graft versus host disease following hematopoietic cell transplantation

2018 ◽  
Vol 53 (7) ◽  
pp. 932-937
Author(s):  
Lucie M. Turcotte ◽  
Tao Wang ◽  
Michael T. Hemmer ◽  
Stephen R. Spellman ◽  
Mukta Arora ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cell Transplantation ◽  
Body Mass ◽  
Graft Versus Host Disease ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Host Disease ◽  
Graft Versus Host

scholarly journals Pediatric Hematopoietic Cell Transplantation: Longitudinal Trends in Body Mass Index and Outcomes

2020 ◽  
Author(s):  
Brian Dang ◽  
Holly Wilhalme ◽  
James Ch ng ◽  
Satiro De Oliveira ◽  
Lavette Bowles ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cell Transplantation ◽  
Body Mass ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell
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