scholarly journals Body Mass Index as an Indicator of Prognosis in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Single Institution Experience

2013 ◽  
Vol 19 (2) ◽  
pp. S219
Author(s):  
Guillermo Jose Ruiz-Delgado ◽  
Julia A. Lutz-Presno ◽  
Carlos Alarcon-Urdaneta ◽  
Guillermo J. Ruiz-Arguelles
Keyword(s):  
Body Mass Index ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Body Mass ◽  
Single Institution ◽  
Hematopoietic Stem

Pretransplant body mass index on outcomes of allogeneic hematopoietic stem cell transplantation

2019 ◽  
Vol 55 (6) ◽  
pp. 1175-1177
Author(s):  
Justin Tai ◽  
Matthew Buras ◽  
Jose Leis ◽  
Pierre Noel ◽  
Jeanne Palmer ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Body Mass ◽  
Hematopoietic Stem

scholarly journals Obesity is correlated with poor outcome after allogeneic hematopoietic stem cell transplantation in patients with acute leukemia

2020 ◽  
Vol 50 (8) ◽  
pp. 889-896
Author(s):  
Jian Yu ◽  
Shangnao Lin ◽  
Yi Luo ◽  
Jimin Shi ◽  
Yamin Tan ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Confidence Interval ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Body Mass ◽  
Normal Weight ◽  
Hematopoietic Stem

Abstract Objective The relationship between body mass index and overall survival has been controversial in patients who suffered from hematological malignancies and underwent hematopoietic stem cell transplantation. Methods We collected the data of 686 acute leukemia patients who received only one allogeneic hematopoietic stem cell transplantation in our center from 2008 to 2017. Patients were divided into four groups (underweight, normal weight, overweight and obesity) according to their body mass index pre-hematopoietic stem cell transplantation. Results 56.4% of patients had normal body mass indices, 17.3% were underweight, 20.4% were overweight and 5.8% were with obesity. Concerning long-term follow-up, the probability of overall survival was significantly lower in overweight (P = 0.010) and patients with obesity (P = 0.065) as compared with normal weight patients, and no statistically significant difference between underweight and normal weight individuals (P = 0.810). The results demonstrated that higher body mass index was associated with poorer overall survival (hazard ratio: 1.79; 95% confidence interval: 1.33–2.40, P < 0.001) and shorter leukemia-free survival (hazard ratio: 1.78; 95% confidence interval: 1.35–2.34, P < 0.001). Additionally, patients exhibiting a higher body mass index were more likely to face the problem of relapse (30.6 vs 20.9%, P < 0.001). Furthermore, non-relapse mortality of patients with obesity was statistically higher than normal weight patients (22.5 vs 9.6%, P = 0.027). Besides, individuals with a higher abdominal girth had shorter survival (hazard ratio: 1.73; 95% confidence interval: 1.29–2.31, P < 0.001) and higher relapse rate (hazard ratio: 1.78; 95% confidence interval: 1.29–2.45, P = 0.001) as compared with those with a lower abdominal girth. Conclusion Our results indicate that obesity at pre-hematopoietic stem cell transplantation stage, whether characterized by higher body mass index or abdominal girth, is correlated with poorer outcome.

Effect of body mass index on outcomes of autologous hematopoietic stem cell transplantation.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e18004-e18004
Author(s):  
Sherilyn Alvaran Tuazon ◽  
Neil David Palmisiano ◽  
Scott W. Keith ◽  
Irina Kakhniashvili ◽  
Joanne E. Filicko-O'Hara
Keyword(s):  
Body Mass Index ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Body Mass ◽  
Hematopoietic Stem
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