Vaccination response following aerobic exercise: Can a brisk walk enhance antibody response to pneumococcal and influenza vaccinations?

2012 ◽  
Vol 26 (4) ◽  
pp. 680-687 ◽  
Author(s):  
Joanna E. Long ◽  
Christopher Ring ◽  
Mark Drayson ◽  
Jos Bosch ◽  
John P. Campbell ◽  
...  
Keyword(s):  
Antibody Response ◽  
Aerobic Exercise ◽  
Vaccination Response ◽  
Influenza Vaccinations ◽  
Enhance Antibody Response

scholarly journals Effect of Duration of a Moderate Exercise Program on Primary and Secondary Immune Responses in Mice

2003 ◽  
Vol 83 (7) ◽  
pp. 638-647 ◽  
Author(s):  
Zoher F Kapasi ◽  
Pamela A Catlin ◽  
Meredith A Adams ◽  
Elizabeth G Glass ◽  
Bart W McDonald ◽  
...  
Keyword(s):  
Antibody Response ◽  
Exercise Program ◽  
Endogenous Opioids ◽  
Exercise Session ◽  
Enzyme Linked Immunosorbent Assay ◽  
Moderate Exercise ◽  
Secondary Antibody ◽  
Primary Immunization ◽  
Antibody Levels ◽  
Enhance Antibody Response

Abstract Background and Purpose. Moderate exercise conducted over a 4- to 8-week period enhances secondary antibody response and is mediated, in part, by endogenous opioids. Because changes in circulating levels of endogenous opioids occur after each exercise session, the researchers in this study tested the hypothesis that a shorter exercise program of 2 weeks may be sufficient to enhance secondary antibody response. Another purpose of this study was to examine the effects of a moderate exercise program completed prior to the primary immunization on the secondary antibody response in mice. Subjects and Methods. Young (8- to 10-week-old), syngeneic, female C57BL/6 mice were randomly assigned to exercise (2 or 8 weeks) and sedentary intervention protocols. Mice were immunized against human serum albumin (HSA), and serum anti-HSA antibody levels were measured (in micrograms per milliliter) using an enzyme-linked immunosorbent assay (ELISA). Results. The secondary antibody response was comparable in mice exercising for 2 or 8 weeks and was enhanced over sedentary controls. Discussion and Conclusion. A moderate exercise program of 2 weeks may be sufficient to improve secondary antibody production and may be a useful strategy to enhance antibody response to vaccinations in humans. Furthermore, an exercise program that includes exercise prior to the primary immunization in addition to exercise following primary immunization may not provide additional enhancement of secondary antibody response.

scholarly journals Different Repeat Annual Influenza Vaccinations Improve the Antibody Response to Drifted Influenza Strains

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Ewan P. Plant ◽  
Lucy J. Fredell ◽  
Blake A. Hatcher ◽  
Xing Li ◽  
Meng-Jung Chiang ◽  
...  
Keyword(s):  
Antibody Response ◽  
Influenza Vaccinations

Adequate immune response to tetanus toxoid and failure of vitamin A and E supplementation to enhance antibody response in healthy children

Vaccine ◽  
2000 ◽  
Vol 18 (26) ◽  
pp. 2979-2984 ◽  
Author(s):  
Necil Kutukculer ◽  
Talha Akil ◽  
Ayten Egemen ◽  
Zafer Kurugöl ◽  
Sadık Akşit ◽  
...  
Keyword(s):  
Immune Response ◽  
Vitamin A ◽  
Antibody Response ◽  
Tetanus Toxoid ◽  
Healthy Children ◽  
Enhance Antibody Response

scholarly journals Antibody Response to Canine Adenovirus-2 Virus Vaccination in Healthy Adult Dogs

Viruses ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 1198
Author(s):  
Michèle Bergmann ◽  
Monika Freisl ◽  
Yury Zablotski ◽  
Stephanie Speck ◽  
Uwe Truyen ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Antibody Response ◽  
Urban Areas ◽  
Multivariate Regression ◽  
Healthy Adult ◽  
Multivariate Regression Analysis ◽  
Exact Test ◽  
Virus Vaccination ◽  
Factors Associated ◽  
Vaccination Response

Background: Re-vaccination against canine adenovirus (CAV) is performed in ≤3-year-intervals but their necessity is unknown. The study determined anti-CAV antibodies within 28 days of re-vaccination and factors associated with the absence of antibodies and vaccination response. Methods: Ninety-seven healthy adult dogs (last vaccination ≥12 months) were re-vaccinated with a modified live CAV-2 vaccine. Anti-CAV antibodies were measured before vaccination (day 0), and after re-vaccination (day 7, 28) by virus neutralization. A ≥4-fold titer increase was defined as vaccination response. Fisher’s exact test and multivariate regression analysis were performed to determine factors associated with the absence of antibodies and vaccination response. Results: Totally, 87% of dogs (90/97; 95% CI: 85.61–96.70) had anti-CAV antibodies (≥10) before re-vaccination. Vaccination response was observed in 6% of dogs (6/97; 95% CI: 2.60–13.11). Time since last vaccination (>3–5 years, OR = 9.375, p = 0.020; >5 years, OR= 25.000, p = 0.006) was associated with a lack of antibodies. Dogs from urban areas were more likely to respond to vaccination (p = 0.037). Conclusion: Many dogs had anti-CAV pre-vaccination antibodies, even those with an incomplete vaccination series. Most dogs did not respond to re-vaccination. Based on this study, dogs should be re-vaccinated every 3 years or antibodies should be determined.

scholarly journals Humoral Antibody Response After Receipt of Inactivated Seasonal Influenza Vaccinations One Year Apart in Children

2012 ◽  
Vol 31 (9) ◽  
pp. 964-969 ◽  
Author(s):  
Sophia Ng ◽  
Vicky J. Fang ◽  
Dennis K. M. Ip ◽  
Susan S. Chiu ◽  
Gabriel M. Leung ◽  
...  
Keyword(s):  
Antibody Response ◽  
Seasonal Influenza ◽  
Humoral Antibody ◽  
One Year ◽  
Influenza Vaccinations

scholarly journals Antibody Response to Canine Parvovirus Vaccination in Dogs with Hypothyroidism Treated with Levothyroxine

Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 180
Author(s):  
Michèle Bergmann ◽  
Monika Freisl ◽  
Katrin Hartmann ◽  
Stephanie Speck ◽  
Uwe Truyen ◽  
...  
Keyword(s):  
Adverse Events ◽  
Antibody Response ◽  
Matched Control ◽  
Univariate Analysis ◽  
Canine Parvovirus ◽  
Post Vaccination ◽  
Vaccination Response ◽  
Significant Difference ◽  
Healthy Dogs ◽  
Modified Live Vaccine

(1) Background: No information is available on how dogs with hypothyroidism (HypoT) respond to vaccination. This study measured pre- and post-vaccination anti-canine parvovirus (CPV) antibodies in dogs with HypoT treated with levothyroxine and compared the results to those of healthy dogs. (2) Methods: Six dogs with HypoT and healthy age-matched control dogs (n = 23) were vaccinated against CPV with a modified-live vaccine. Hemagglutination inhibition was used to measure antibodies on days 0, 7, and 28. The comparison of the vaccination response of dogs with HypoT and healthy dogs were performed with univariate analysis. (3) Results: Pre-vaccination antibodies (≥10) were detected in 100% of dogs with HypoT (6/6; 95% CI: 55.7–100) and in 100% of healthy dogs (23/23; 95% CI: 83.1–100.0). A ≥4-fold titer increase was observed in none of the dogs with HypoT and in 4.3% of the healthy dogs (1/23; CI95%: <0.01–22.7). Mild vaccine-associated adverse events (VAAEs) were detected in 33.3% of the dogs with HypoT (2/6; 95% CI: 9.3–70.4) and in 43.5% (10/23; 95% CI: 25.6–63.2) of the healthy dogs. (4) Conclusions: There was neither a significant difference in the dogs’ pre-vaccination antibodies (p = 1.000), or vaccination response (p = 0.735), nor in the occurrence of post-vaccination VAAEs (p = 0.798). The vaccination response in dogs with levothyroxine-treated HypoT seems to be similar to that of healthy dogs.

scholarly journals Relationship between Vitamin D Status and Antibody Response to COVID-19 mRNA Vaccination in Healthy Adults

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1714
Author(s):  
Thilo Samson Chillon ◽  
Kamil Demircan ◽  
Raban Arved Heller ◽  
Ines Maria Hirschbil-Bremer ◽  
Joachim Diegmann ◽  
...  
Keyword(s):  
Vitamin D ◽  
Immune Response ◽  
Immune System ◽  
Antibody Response ◽  
Healthy Adults ◽  
Vitamin D Status ◽  
Vaccination Response ◽  
Over Time

The immune response to vaccination with SARS-CoV-2 vaccines varies greatly from person to person. In addition to age, there is evidence that certain micronutrients influence the immune system, particularly vitamin D. Here, we analysed SARS-CoV-2 IgG and neutralisation potency along with 25-hydroxy-cholecalciferol [25(OH)D] concentrations in a cohort of healthy German adults from the time of vaccination over 24 weeks. Contrary to our expectations, no significant differences were found in the dynamic increase or decrease of SARS-CoV-2 IgG as a function of the 25(OH)D status. Furthermore, the response to the first or second vaccination, the maximum SARS-CoV-2 IgG concentrations achieved, and the decline in SARS-CoV-2 IgG concentrations over time were not related to 25(OH)D status. We conclude that the vaccination response, measured as SARS-CoV-2 IgG concentration, does not depend on 25(OH)D status in healthy adults with moderate vitamin D status.

Sign in / Sign up

Export Citation Format

Share Document