The role of biologic therapies in the management of systemic vasculitis

2006 ◽  
Vol 5 (4) ◽  
pp. 273-278 ◽  
Author(s):  
A.T. Chan ◽  
O. Floßmann ◽  
C. Mukhtyar ◽  
D.R.W. Jayne ◽  
R.A. Luqmani
Keyword(s):  
Systemic Vasculitis ◽  
Biologic Therapies

scholarly journals Vasculitis: From Target Molecules to Novel Therapeutic Approaches

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 757
Author(s):  
Sang-Wan Chung
Keyword(s):  
Systemic Vasculitis ◽  
Alkylating Agents ◽  
Large Vessel Vasculitis ◽  
Large Vessel ◽  
Biologic Therapies ◽  
Therapeutic Approaches ◽  
Novel Treatments ◽  
Treatment Regimens ◽  
Immune Mediated ◽  
Target Molecules

Systemic vasculitis is a group of diverse diseases characterized by immune-mediated inflammation of blood vessels. Current treatments for vasculitis, such as glucocorticoids and alkylating agents, are associated with significant side effects. In addition, the management of both small and large vessel vasculitis is challenging due to a lack of robust markers of disease activity. Recent research has advanced our understanding of the pathogenesis of both small and large vessel vasculitis, and this has led to the development of novel biologic therapies capable of targeting key cytokine and cellular effectors of the inflammatory cascade. It is anticipated that these novel treatments will lead to more effective and less toxic treatment regimens for patients with systemic vasculitis.

The Role of Biologic Therapies in Dermatology

2015 ◽  
Vol 99 (6) ◽  
pp. 1183-1194 ◽  
Author(s):  
Ramin Fathi ◽  
April Wang Armstrong
Keyword(s):  
Biologic Therapies

The Expanding Role of Imaging in Systemic Vasculitis

2016 ◽  
Vol 42 (4) ◽  
pp. 733-751 ◽  
Author(s):  
Sergio Prieto-González ◽  
Georgina Espígol-Frigolé ◽  
Ana García-Martínez ◽  
Marco A. Alba ◽  
Itziar Tavera-Bahillo ◽  
...  
Keyword(s):  
Systemic Vasculitis

Inflammatory bowel disease and colonic disorders

2021 ◽  
pp. 150-208
Author(s):  
Thomas Marjot
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Core Curriculum ◽  
Therapeutic Drug ◽  
Biologic Therapies ◽  
Inflammatory Bowel ◽  
Prevention Of Cancer ◽  
Curriculum Topics

This chapter covers core curriculum topics relating to inflammatory bowel disease (IBD) and colonic disorders. A diagnostic approach to IBD is covered including the role of imaging, endoscopy, histopathology and clinical features. Pathophysiology and epidemiology of IBD is detailed. Management of Ulcerative colitis and Crohn’s disease includes assessment of disease severity, imaging modalities and therapeutic management. Particular focus is given to therapeutic drug monitoring and indications for biologic therapies. Surgical management of IBD is broadly covered including indications, timing and approach. Coverage is also given to the diagnosis and management of extra-intestinal manifestations of IBD, IBD in special situations (pregnancy, elderly, transition) and the prevention of cancer in IBD. Colorectal cancer and benign conditions including constipation, functional gut disorders and other colitides are also featured.

Role of therapeutic plasma exchanges in systemic vasculitis

2020 ◽  
Vol 59 (6) ◽  
pp. 102992
Author(s):  
Alexis Régent ◽  
Luc Mouthon ◽  
Loïc Guillevin ◽  
Benjamin Terrier
Keyword(s):  
Systemic Vasculitis
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