Interaction of osteoblast -TiO2 nanotubes in vitro: The combinatorial effect of surface topography and other physico-chemical factors governs the cell fate

2018 ◽  
Vol 449 ◽  
pp. 152-165 ◽  
Author(s):  
Sahely Saha ◽  
Ravi Kumar ◽  
Krishna Pramanik ◽  
Amit Biswas
Keyword(s):  
Surface Topography ◽  
Cell Fate ◽  
Tio2 Nanotubes ◽  
Physico Chemical ◽  
Chemical Factors ◽  
Effect Of Surface

In vitro oral drug permeation models: the importance of taking physiological and physico-chemical factors into consideration

2016 ◽  
Vol 14 (2) ◽  
pp. 179-187 ◽  
Author(s):  
Ruan Joubert ◽  
Johan Dewald Steyn ◽  
Hendrik Jacobus Heystek ◽  
Jan Harm Steenekamp ◽  
Jan Lourens Du Preez ◽  
...  
Keyword(s):  
Oral Drug ◽  
Drug Permeation ◽  
Physico Chemical ◽  
Chemical Factors ◽  
Permeation Models

1234 Evaluation of effect of surface topography on fixation of artificial joint in vitro

2005 ◽  
Vol 2005.5 (0) ◽  
pp. 209-210
Author(s):  
Kenichi YAMASAKI ◽  
Koji HATTORI ◽  
Hideo KONDO ◽  
Shigehiro HASHIMOTO ◽  
Yoshinori TAKAKURA ◽  
...  
Keyword(s):  
Surface Topography ◽  
Artificial Joint ◽  
Effect Of Surface

Cytotoxicity and Adhesion Evaluation of Nanothickness Ca/P-Based Bioceramics Coated Titanium

2008 ◽  
Vol 396-398 ◽  
pp. 319-322
Author(s):  
Caroline M. Ramirez ◽  
Paulo Guilherme Coelho ◽  
José Mauro Granjeiro
Keyword(s):  
Cell Adhesion ◽  
Surface Topography ◽  
Dental Implants ◽  
Biological Response ◽  
Biological Evaluation ◽  
Titanium Implants ◽  
3T3 Fibroblasts ◽  
Plasma Sprayed ◽  
Effect Of Surface

Incorporation of bioceramics on the surface of dental implants has been utilized in an attempt to increase biological response of bone to materials. This paper reports the in vitro biological evaluation of Ca/P-based nanothickness bioceramic coated alumina-blasted/acid-etched titanium implants (AB/AE nanotite implant) and compare its performance to the untreated and uncoated implants, Ca/P-based nanothickness bioceramic coated untreated implants (untreated nanotite implant), alumina-blasted/acid-etched titanium implants (AB/AE implant) and hydroxyapatite plasma-sprayed implants (PSHA Implant). Balb/c 3T3 fibroblasts were used to asses the cytocompatibility of implant materials according to ISO-10993-5 protocols. Osteoblasts from Balb/c femurs seeded onto different implant surfaces showed the effect of surface topography and chemistry on cell adhesion. The results showed that all implants were not cytotoxic and that PSHA and AB/AE nanotite implants favored osteoblasts adhesion.

THYROID STIMULATORS AND THYROID STIMULATION

1971 ◽  
Vol 66 (3) ◽  
pp. 558-576 ◽  
Author(s):  
Gerald Burke
Keyword(s):  
Regulatory System ◽  
Control Site ◽  
Thyroid Cell ◽  
Primary Control ◽  
Physico Chemical ◽  
Site Of Action ◽  
Long Acting

ABSTRACT A long-acting thyroid stimulator (LATS), distinct from pituitary thyrotrophin (TSH), is found in the serum of some patients with Graves' disease. Despite the marked physico-chemical and immunologic differences between the two stimulators, both in vivo and in vitro studies indicate that LATS and TSH act on the same thyroidal site(s) and that such stimulation does not require penetration of the thyroid cell. Although resorption of colloid and secretion of thyroid hormone are early responses to both TSH and LATS, available evidence reveals no basic metabolic pathway which must be activated by these hormones in order for iodination reactions to occur. Cyclic 3′, 5′-AMP appears to mediate TSH and LATS effects on iodination reactions but the role of this compound in activating thyroidal intermediary metabolism is less clear. Based on the evidence reviewed herein, it is suggested that the primary site of action of thyroid stimulators is at the cell membrane and that beyond the(se) primary control site(s), there exists a multifaceted regulatory system for thyroid hormonogenesis and cell growth.

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