Severe hypoglycemia with “Big”-IGF-2 oversecretion by a giant phyllode tumor of the breast: A rare case of non-islet cell tumor-induced hypoglycemia (NICTH)

2012 ◽  
Vol 73 (5) ◽  
pp. 488-491 ◽  
Author(s):  
Emeline Renard ◽  
Christelle Langbour-Remy ◽  
Marc Klein ◽  
Yves Le Bouc ◽  
Georges Weryha ◽  
...  
Keyword(s):  
Islet Cell ◽  
Rare Case ◽  
Islet Cell Tumor ◽  
Severe Hypoglycemia ◽  
Cell Tumor ◽  
Phyllode Tumor

scholarly journals An Adrenocortical Carcinoma Associated with Non-Islet Cell Tumor Hypoglycemia and Aberrant ACTH Production

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
M. D. S. A. Dilrukshi ◽  
A. W. Wickramarachchi ◽  
D. D. K. Abeyaratne ◽  
Brian Shine ◽  
Bahram Jafar-Mohammadi ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Islet Cell ◽  
Islet Cell Tumor ◽  
Severe Hypoglycemia ◽  
Cushing's Syndrome ◽  
Cell Tumor ◽  
Adrenocortical Carcinomas ◽  
Tumor Hypoglycemia

Introduction. Adrenocortical carcinomas (ACCs) are infrequently reported to present with severe hypoglycemia syndrome resulting from the secretion of insulin-like growth factor II (IGF-II) by tumor cells. Adrenocorticotropic hormone- (ACTH) independent hypercortisolism is the norm of hormonally active ACCs, but aberrant ACTH production by tumor cells can theoretically cause ACTH-dependent hypercortisolism. The purpose of this report was to present a case of an ACC manifested with the co-occurrence of two extremely rare presentations. Case Description. We present a rare case of a 43-year-old male patient admitted with recurrent episodes of severe non-ketotic and non-insulin-mediated hypoglycemia due to IGF-II mediated disease and ACTH-dependent Cushing’s syndrome. He was diagnosed with a diffusely disseminated adrenocortical carcinoma with immunohistochemistry of tumor cells showing focal ACTH immunostain positivity. Conclusion. Non-islet cell tumor hypoglycemia and ACTH-dependent Cushing’s syndrome are extremely rare presentations of an ACC, and co-occurrence of these entities in a single patient is never reported in the literature.

ISLET CELL ADENOMA IN THE NEWBORN: REPORT OF TWO PATIENTS

PEDIATRICS ◽  
1971 ◽  
Vol 48 (2) ◽  
pp. 232-236
Author(s):  
M. J. Robinson ◽  
A. Murray Clarke ◽  
Hugo Gold ◽  
J. F. Connelly
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumor ◽  
Severe Hypoglycemia ◽  
Cell Tumor ◽  
Normal Birth Weight ◽  
Neonatal Hypoglycemia ◽  
Cell Adenoma ◽  
Subtotal Pancreatectomy ◽  
Normal Birth ◽  
Obscure Origin

Islet cell adenoma is a rare cause of severe neonatal hypoglycemia. Two cases are reported and difficulties in diagnosis are outlined. In one infant, cure followed subtotal pancreatectomy at the age of 19 days. It is suggested that severe hypoglycemia of obscure origin persisting beyond the age of 2 weeks in a newborn infant of normal birth weight and not responding to standard medical measures, justifies exploration of the pancreas. Even if an islet-cell tumor is not identified, subtotal pancreatectomy is indicated.

scholarly journals Non-islet-cell tumor hypoglycemia as first manifestation of an advanced hepatocellular carcinoma

2021 ◽  
Author(s):  
Imen Rojbi ◽  
Wiem Ben Elhaj ◽  
Nadia Mchirgui ◽  
myriam jrad ◽  
Ibtissem Ben Nacef ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Islet Cell ◽  
Islet Cell Tumor ◽  
Severe Hypoglycemia ◽  
Clinical Work ◽  
Cell Tumor ◽  
Severe Complication ◽  
Advanced Hepatocellular Carcinoma ◽  
Tumor Hypoglycemia

Non-islet cell tumor hypoglycemia (NICTH) is a rare but severe complication of malignancy. We present the case of 55 year old man who was admitted for severe hypoglycemia. The diagnosis of insulinoma was ruled out. After clinical work-ups, we made the diagnosis of metastatic HCC with production of IGF-2.

About a rare case of hypoglycemia: Non-islet cell tumor hypoglycemia (NICTH)

2021 ◽  
Vol 68 (8) ◽  
pp. 589-591
Author(s):  
Roberto Sierra-Poyatos ◽  
Jersy Cárdenas-Salas ◽  
Maite Ortega-Juaristi ◽  
Clotilde Vázquez-Martínez
Keyword(s):  
Islet Cell ◽  
Rare Case ◽  
Islet Cell Tumor ◽  
Cell Tumor ◽  
Tumor Hypoglycemia

A rare case: non-islet cell tumor hypoglycemia with adrenal insufficiency

2017 ◽  
Author(s):  
Veysi Asoglu ◽  
Mehmet Celik ◽  
Buket Yilmaz Bulbul ◽  
Semra Ayturk ◽  
Funda Ustun ◽  
...  
Keyword(s):  
Adrenal Insufficiency ◽  
Islet Cell ◽  
Rare Case ◽  
Islet Cell Tumor ◽  
Cell Tumor ◽  
Tumor Hypoglycemia

About a rare case of hypoglycemia: Non-islet cell tumor hypoglycemia (NICTH)

2020 ◽  
Author(s):  
Roberto Sierra-Poyatos ◽  
Jersy Cárdenas-Salas ◽  
Maite Ortega-Juaristi ◽  
Clotilde Vázquez-Martínez
Keyword(s):  
Islet Cell ◽  
Rare Case ◽  
Islet Cell Tumor ◽  
Cell Tumor ◽  
Tumor Hypoglycemia

scholarly journals Severe Hypoglycemia Induced by IGF-II Producing Non-Islet Cell Tumor

2007 ◽  
Vol 46 (13) ◽  
pp. 1061-1061 ◽  
Author(s):  
Motoko Kanzaki ◽  
Hiromi Kashihara ◽  
Katsuyuki Kiura ◽  
Kazutoshi Murakami ◽  
Hiromi Iwagaki ◽  
...  
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumor ◽  
Severe Hypoglycemia ◽  
Cell Tumor

Suppression and stimulation mechanisms controlling glucagon secretion in a case of islet-cell tumor producing glucagon, insulin, and gastrin

Diabetes ◽  
1976 ◽  
Vol 25 (5) ◽  
pp. 408-412 ◽  
Author(s):  
A. Tiengo ◽  
D. Fedele ◽  
E. Marchiori ◽  
R. Nosadini ◽  
M. Muggeo
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumor ◽  
Glucagon Secretion ◽  
Cell Tumor
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