Clinical usefulness of videocapillaroscopy and selected endothelial cell activation markers in people with Type 1 diabetes mellitus complicated by microangiopathy

2017 ◽  
Vol 62 (2) ◽  
pp. 368-373 ◽  
Author(s):  
Anna Kuryliszyn-Moskal ◽  
Wieslaw Zarzycki ◽  
Artur Dubicki ◽  
Diana Moskal ◽  
Bozena Kosztyła-Hojna ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Endothelial Cell ◽  
Type 1 Diabetes Mellitus ◽  
Cell Activation ◽  
Clinical Usefulness ◽  
Endothelial Cell Activation ◽  
Activation Markers

scholarly journals Markers of apoptosis in patients with type 1 diabetes mellitus at the onset of the disease

2009 ◽  
Vol 12 (4) ◽  
pp. 73-89 ◽  
Author(s):  
Elena Vladimirovna Pekareva ◽  
Tatiana Vasil'evna Nikonova ◽  
Vera Anatol'evna Gorelysheva ◽  
Yana Stanislavovna Zvereva ◽  
Svetlana Mikhailovna Stepanova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Immune Response ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Peripheral Blood Lymphocytes ◽  
Activation Markers ◽  
Activated Lymphocytes ◽  
Immunological Examination ◽  
Biochemical Genetic

Aim. This work was to study activation markers of apoptosis (CD95, CD95L) on peripheral blood lymphocytes of patients with type 1 diabetes mellitus (DM1) at the onset of the disease. Materials and methods. A total of 33 patients (25 men and 8 women) divided into 2 groups were available for biochemical, genetic, and immunological examination. Results. Those with the ?classical? onset of DM1 had significantly fewer CD95-expressing lymphocytes and more CD95L+ lymphocytes than control subjects. Carriers of genes responsible for high risk of DM1 showed especially large number of lymphocytes expressing CD95L. Conclusion. It is conjectured that DM1 is characterized by the suppression of mechanism controlling apoptosis of activated lymphocytes that may promote prolongation of the immune response.

scholarly journals T Cell Activation by Coxsackievirus B4 Antigens in Type 1 Diabetes Mellitus: Evidence for Selective TCR Vβ Usage Without Superantigenic Activity

2001 ◽  
Vol 167 (6) ◽  
pp. 3513-3520 ◽  
Author(s):  
Ruben Varela-Calvino ◽  
Gianluca Sgarbi ◽  
Lucy R. Wedderburn ◽  
Colin M. Dayan ◽  
Jenny Tremble ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
T Cell ◽  
Type 1 Diabetes Mellitus ◽  
T Cell Activation ◽  
Cell Activation ◽  
Coxsackievirus B4

Selective Inhibition of FcεRI-Mediated Mast Cell Activation by a Truncated Variant of Cbl-b Related to the Rat Model of Type 1 Diabetes Mellitus

2005 ◽  
Vol 137 (6) ◽  
pp. 711-720 ◽  
Author(s):  
Xiujuan Qu ◽  
S. M. Shahjahan Miah ◽  
Tomoko Hatani ◽  
Mami Okazaki ◽  
Naoko Hori-Tamura ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Mast Cell ◽  
Type 1 Diabetes Mellitus ◽  
Rat Model ◽  
Cell Activation ◽  
Selective Inhibition ◽  
Mast Cell Activation
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