Extracellular matrix-inspired growth factor delivery systems for bone regeneration

2015 ◽  
Vol 94 ◽  
pp. 41-52 ◽  
Author(s):  
Mikaël M. Martino ◽  
Priscilla S. Briquez ◽  
Kenta Maruyama ◽  
Jeffrey A. Hubbell
Keyword(s):  
Extracellular Matrix ◽  
Growth Factor ◽  
Bone Regeneration ◽  
Delivery Systems ◽  
Growth Factor Delivery

scholarly journals Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing

2015 ◽  
Vol 4 (8) ◽  
pp. 479-489 ◽  
Author(s):  
Priscilla S. Briquez ◽  
Jeffrey A. Hubbell ◽  
Mikaël M. Martino
Keyword(s):  
Extracellular Matrix ◽  
Wound Healing ◽  
Growth Factor ◽  
Delivery Systems ◽  
Skin Wound ◽  
Growth Factor Delivery ◽  
Skin Wound Healing

scholarly journals Double-layered microsphere based dual growth factor delivery system for guided bone regeneration

RSC Advances ◽  
2018 ◽  
Vol 8 (30) ◽  
pp. 16503-16512 ◽  
Author(s):  
Chun Xu ◽  
Jia Xu ◽  
Lan Xiao ◽  
Zhihao Li ◽  
Yin Xiao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Growth Factor ◽  
Bone Regeneration ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Guided Bone Regeneration ◽  
Delivery Systems ◽  
Growth Factor Delivery ◽  
Dual Growth Factor Delivery

Microsphere based drug delivery systems show great advantages for tissue engineering.

scholarly journals Advances in Growth Factor Delivery for Bone Tissue Engineering

2021 ◽  
Vol 22 (2) ◽  
pp. 903
Author(s):  
Érica Resende Oliveira ◽  
Lei Nie ◽  
Daria Podstawczyk ◽  
Ahmad Allahbakhsh ◽  
Jithendra Ratnayake ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Growth Factors ◽  
Growth Factor ◽  
Bone Tissue Engineering ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Bone Repair ◽  
Bone Diseases ◽  
Growth Factor Delivery

Shortcomings related to the treatment of bone diseases and consequent tissue regeneration such as transplants have been addressed to some extent by tissue engineering and regenerative medicine. Tissue engineering has promoted structures that can simulate the extracellular matrix and are capable of guiding natural bone repair using signaling molecules to promote osteoinduction and angiogenesis essential in the formation of new bone tissues. Although recent studies on developing novel growth factor delivery systems for bone repair have attracted great attention, taking into account the complexity of the extracellular matrix, scaffolding and growth factors should not be explored independently. Consequently, systems that combine both concepts have great potential to promote the effectiveness of bone regeneration methods. In this review, recent developments in bone regeneration that simultaneously consider scaffolding and growth factors are covered in detail. The main emphasis in this overview is on delivery strategies that employ polymer-based scaffolds for spatiotemporal-controlled delivery of both single and multiple growth factors in bone-regeneration approaches. From clinical applications to creating alternative structural materials, bone tissue engineering has been advancing constantly, and it is relevant to regularly update related topics.

Triple Growth Factor Delivery Promotes Functional Bone Regeneration Following Composite Musculoskeletal Trauma

2021 ◽  
Author(s):  
Ramesh Subbiah ◽  
Marissa A. Ruehle ◽  
Brett S. Klosterhoff ◽  
Angela S.P. Lin ◽  
Marian H. Hettiaratchi ◽  
...  
Keyword(s):  
Growth Factor ◽  
Bone Regeneration ◽  
Growth Factor Delivery ◽  
Musculoskeletal Trauma

scholarly journals Integrated approach to designing growth factor delivery systems

2007 ◽  
Vol 21 (14) ◽  
pp. 3896-3903 ◽  
Author(s):  
Ruth R. Chen ◽  
Eduardo A. Silva ◽  
William W. Yuen ◽  
Andrea A. Brock ◽  
Claudia Fischbach ◽  
...  
Keyword(s):  
Growth Factor ◽  
Integrated Approach ◽  
Delivery Systems ◽  
Growth Factor Delivery

A platelet derived growth factor delivery system for bone regeneration

2012 ◽  
Vol 23 (8) ◽  
pp. 1903-1912 ◽  
Author(s):  
J. J. Delgado ◽  
Esther Sánchez ◽  
Manuel Baro ◽  
Ricardo Reyes ◽  
Carmen Évora ◽  
...  
Keyword(s):  
Growth Factor ◽  
Bone Regeneration ◽  
Delivery System ◽  
Platelet Derived Growth Factor ◽  
Growth Factor Delivery
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