The Taxus™ drug-eluting stent: A new paradigm in controlled drug delivery

2006 ◽  
Vol 58 (3) ◽  
pp. 412-436 ◽  
Author(s):  
Kalpana R. Kamath ◽  
James J. Barry ◽  
Kathleen M. Miller
Keyword(s):  
Drug Delivery ◽  
Controlled Drug Delivery ◽  
Drug Eluting Stent ◽  
New Paradigm ◽  
Drug Eluting

Drug-eluting stent with rhombic-shape reservoirs for drug delivery

2016 ◽  
Author(s):  
Yen-Ting Wang ◽  
Yi-Ping Wang ◽  
Tzu-Yuan Lin ◽  
Chien-Erh Lin ◽  
Hao-Ming Hsiao
Keyword(s):  
Drug Delivery ◽  
Drug Eluting Stent ◽  
Drug Eluting

scholarly journals Drug-eluting contact lens containing cyclosporine-loaded cholesterol-hyaluronate micelles for dry eye syndrome

RSC Advances ◽  
2019 ◽  
Vol 9 (29) ◽  
pp. 16578-16585 ◽  
Author(s):  
Jonghwan Mun ◽  
Jee won Mok ◽  
Sanghoon Jeong ◽  
Seonghwi Cho ◽  
Choun-Ki Joo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dry Eye ◽  
Contact Lens ◽  
Drug Loading ◽  
Controlled Drug Delivery ◽  
Dry Eye Syndrome ◽  
Hydrophobic Drug ◽  
Drug Eluting

A cholesterol-hyaluronate (C-HA) micelle embedded contact lens was developed for efficient hydrophobic drug loading and long-term controlled drug delivery.

Neointima Inhibition: Comparison of Effectiveness of Non–Stent-based Local Drug Delivery and a Drug-eluting Stent in Porcine Coronary Arteries

Radiology ◽  
2006 ◽  
Vol 240 (2) ◽  
pp. 411-418 ◽  
Author(s):  
Ulrich Speck ◽  
Bruno Scheller ◽  
Claudia Abramjuk ◽  
Christoph Breitwieser ◽  
Juergen Dobberstein ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Coronary Arteries ◽  
Local Drug Delivery ◽  
Drug Eluting Stent ◽  
Drug Eluting ◽  
Comparison Of Effectiveness

scholarly journals Mutual influence of incorporated drugs in a dual drug delivery coating for cardiovascular applications

2017 ◽  
Vol 3 (2) ◽  
pp. 379-382
Author(s):  
Katharina Wulf ◽  
Michael Teske ◽  
Claudia Matschegewski ◽  
Daniela Arbeiter ◽  
Thomas Eickner ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mutual Influence ◽  
Local Drug Delivery ◽  
Drug Eluting Stent ◽  
Vascular Endothelial ◽  
Effective Inhibition ◽  
Drug Eluting ◽  
The Stability ◽  
Endothelial Growth Factor

AbstractFor a long-term efficient drug-eluting stent for vascular applications, the development of drug-loaded coating, combining the effective inhibition of smooth muscle cell proliferation while promoting the re-endothelialization, is a promising concept. However the mostly required simultaneous incorporation of drugs can influence decisively the stability, efficacy and release of the respective drug. Therefore, the mutual influence of a dual local drug delivery coatings based on poly(L-lactide-co-ε-caprolactone) (PLLA-co-CL) containing vascular endothelial growth factor (VEGF165) coupled to the surface and an embedded drug, such as fluorescein diacetate (FDAc) instead of Paclitaxel (PTX) on the in vitro drug release was investigated. Surprisingly, for the investigated coating the immobilized VEGF loading was enhanced and the release profile was accelerated by FDAc incorporation. Even a manifold increase for the in vitro released amounts of VEGF was detected. In contrast, the immobilization of VEGF seems to have a negligible influence on the in vitro FDAc release profiles.

Non-vascular drug eluting stents as localized controlled drug delivery platform: Preclinical and clinical experience

2013 ◽  
Vol 172 (1) ◽  
pp. 105-117 ◽  
Author(s):  
Mohsin Shaikh ◽  
Ganessan Kichenadasse ◽  
Namita Roy Choudhury ◽  
Ross Butler ◽  
Sanjay Garg
Keyword(s):  
Drug Delivery ◽  
Clinical Experience ◽  
Controlled Drug Delivery ◽  
Drug Eluting Stents ◽  
Drug Eluting ◽  
Delivery Platform

Drug Eluting Stent: A Promising Drug Delivery System

2009 ◽  
Vol 1 (1) ◽  
Author(s):  
Rakesh Patel ◽  
Samir Patel ◽  
Chetan Borkhataria
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Pharmacological Therapy ◽  
Drug Eluting Stents ◽  
Drug Eluting Stent ◽  
Broad Perspective ◽  
New Device ◽  
Drug Eluting ◽  
Time Periods ◽  
High Doses

TDrug eluting stent is a topic of current interest in the design of drug delivery systems. Drug-eluting stents deliver potentially high doses of drugs locally for variable time periods in the area of stent implantation, directed at the potential restenosis site. While this is currently achievable, optimal pharmacological therapy is still evolving. Acknowledging the challenge of examining such a dynamic and flourishing field, our goals in this article were to provide a broad perspective of the development of drug-eluting stent technology, to summarize the available clinical data, and to introduce emerging concepts for the understanding and application of this new device in clinical practice.

scholarly journals Local drug-delivery balloon for proliferative occlusive in-stent restenosis after drug-eluting stent

2011 ◽  
Vol 8 (1) ◽  
pp. 65-66
Author(s):  
Rigatelli Gianluca ◽  
Cardaioli Paolo ◽  
Dell’Avvocata Fabio ◽  
Giordan Massimo
Keyword(s):  
Drug Delivery ◽  
Local Drug Delivery ◽  
Drug Eluting Stent ◽  
Stent Restenosis ◽  
Drug Eluting ◽  
In Stent Restenosis
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