scholarly journals Age of alcohol use initiation and psychiatric symptoms among young adult trauma survivors

2019 ◽  
Vol 88 ◽  
pp. 150-156 ◽  
Author(s):  
Erin C. Berenz ◽  
Sage McNett ◽  
Lance M. Rappaport ◽  
Anka A. Vujanovic ◽  
Andres G. Viana ◽  
...  
PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0202200 ◽  
Author(s):  
Haika Osaki ◽  
Gerry Mshana ◽  
Doris Mbata ◽  
Saidi Kapiga ◽  
John Changalucha

2019 ◽  
Vol 80 (6) ◽  
pp. 623-630 ◽  
Author(s):  
Brian A. Feinstein ◽  
Isaac C. Rhew ◽  
Kimberley A. Hodge ◽  
Tonda L. Hughes ◽  
Debra Kaysen

2019 ◽  
Vol 44 (1) ◽  
pp. 255-263
Author(s):  
Jacqueline Woerner ◽  
Feifei Ye ◽  
Alison E. Hipwell ◽  
Tammy Chung ◽  
Carolyn E. Sartor

2018 ◽  
Vol 49 (5) ◽  
pp. 791-800 ◽  
Author(s):  
Erika J. Wolf ◽  
Mark W. Logue ◽  
Filomene G. Morrison ◽  
Elizabeth S. Wilcox ◽  
Annjanette Stone ◽  
...  

AbstractBackgroundPosttraumatic stress disorder (PTSD) and stress/trauma exposure are cross-sectionally associated with advanced DNA methylation age relative to chronological age. However, longitudinal inquiry and examination of associations between advanced DNA methylation age and a broader range of psychiatric disorders is lacking. The aim of this study was to examine if PTSD, depression, generalized anxiety, and alcohol-use disorders predicted acceleration of DNA methylation age over time (i.e. an increasing pace, or rate of advancement, of the epigenetic clock).MethodsGenome-wide DNA methylation and a comprehensive set of psychiatric symptoms and diagnoses were assessed in 179 Iraq/Afghanistan war veterans who completed two assessments over the course of approximately 2 years. Two DNA methylation age indices (Horvath and Hannum), each a weighted index of an array of genome-wide DNA methylation probes, were quantified. The pace of the epigenetic clock was operationalized as change in DNA methylation age as a function of time between assessments.ResultsAnalyses revealed that alcohol-use disorders (p = 0.001) and PTSD avoidance and numbing symptoms (p = 0.02) at Time 1 were associated with an increasing pace of the epigenetic clock over time, per the Horvath (but not the Hannum) index of cellular aging.ConclusionsThis is the first study to suggest that posttraumatic psychopathology is longitudinally associated with a quickened pace of the epigenetic clock. Results raise the possibility that accelerated cellular aging is a common biological consequence of stress-related psychopathology, which carries implications for identifying mechanisms of stress-related cellular aging and developing interventions to slow its pace.


2020 ◽  
Vol 50 (4) ◽  
pp. 359-377
Author(s):  
Akilah Patterson ◽  
Milkie Vu ◽  
Regine Haardörfer ◽  
Michael Windle ◽  
Carla J. Berg

This study examined (a) differences between alcohol-only users and alcohol–marijuana co-users and (b) motives for use in relation to alcohol and marijuana use and problem use. Spring 2016 data among 1,870 past 4-month alcohol users (63.6% female, 69.1% White) from seven Georgia colleges/universities were analyzed cross-sectionally and with regard to problem use measured 4 months later. Correlates of co-use ( n = 345; vs. alcohol-only use, n = 1,525) included greater alcohol and marijuana use frequency, problem drinking and marijuana use, and alcohol use motives ( p’s < .05). Controlling for covariates, alcohol use frequency correlated with greater marijuana use frequency and Coping and Self-enhancement alcohol use motives, but lower Conformity alcohol use motives ( p’s < .001); greater Coping and Self-enhancement alcohol use motives ( p’s < .01) predicted problem alcohol use. Marijuana use frequency correlated with greater Coping and Expansion marijuana use motives ( p’s < .05); greater Expansion marijuana use motives ( p = .005) predicted problem marijuana use. College-based substance use interventions should target Coping and Self-enhancement alcohol use motives and Expansion marijuana use motives.


2020 ◽  
Vol 19 ◽  
pp. 100298
Author(s):  
Nicolas Bertholet ◽  
Jean-Bernard Daeppen ◽  
Joseph Studer ◽  
Emily C. Williams ◽  
John A. Cunningham ◽  
...  

Author(s):  
Lucas Giner ◽  
Juan J Carballo ◽  
Julio A Guija ◽  
Dahlia Sperling ◽  
Maria A Oquendo ◽  
...  

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