Major depression among adolescent smokers undergoing treatment for nicotine dependence

2004 ◽  
Vol 29 (8) ◽  
pp. 1517-1526 ◽  
Author(s):  
Joel D. Killen ◽  
Thomas N. Robinson ◽  
Seth Ammerman ◽  
Chris Hayward ◽  
Jayna Rogers ◽  
...  
Keyword(s):  
Major Depression ◽  
Nicotine Dependence ◽  
Adolescent Smokers

A twin study of smoking, nicotine dependence, and major depression in men

2008 ◽  
Vol 10 (1) ◽  
pp. 97-108 ◽  
Author(s):  
Michael Lyons ◽  
Brian Hitsman ◽  
Hong Xian ◽  
Matthew Panizzon ◽  
Beth Jerskey ◽  
...  
Keyword(s):  
Major Depression ◽  
Nicotine Dependence ◽  
Twin Study

scholarly journals Testing the nicotine dependence measure mFTQ for adolescent smokers: A multinational investigation

2017 ◽  
Vol 26 (7) ◽  
pp. 689-696 ◽  
Author(s):  
Alexander V. Prokhorov ◽  
Georges E. Khalil ◽  
Dawn W. Foster ◽  
Salma K. Marani ◽  
Michele Guindani ◽  
...  
Keyword(s):  
Nicotine Dependence ◽  
Adolescent Smokers ◽  
Dependence Measure

scholarly journals Common Genetic Risk of Major Depression and Nicotine Dependence: The Contribution of Antisocial Traits in a United States Veteran Male Twin Cohort

2007 ◽  
Vol 10 (3) ◽  
pp. 470-478 ◽  
Author(s):  
Qiang Fu ◽  
Andrew C. Heath ◽  
Kathleen K. Bucholz ◽  
Michael J. Lyons ◽  
Ming T. Tsuang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depression ◽  
Predominantly White ◽  
Nicotine Dependence ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
Diagnostic Interview ◽  
Genetic Influences ◽  
Vietnam Era ◽  
Shared Genetic

AbstractMany studies that found associations between depression and nicotine dependence have ignored possible shared genetic influences associated with antisocial traits. The present study examined the contribution of genetic and environmental effects associated with conduct disorder (CD) and antisocial personality disorder (ASPD) to the comorbidity of major depression (MD) and nicotine dependence (ND). A telephone diagnostic interview, the Diagnostic Interview Schedule-III-R, was administered to eligible twins from the Vietnam Era Twin (VET) Registry in 1992. Multivariate genetic models were fitted to 3360 middle-aged and predominantly white twin pairs (1868 monozygotic, 1492 dizygotic pairs) of which both members completed the pertinent diagnostic interview sections. Genetic influences on CD accounted for 100%, 68%, and 50% of the total genetic variance in risk for ASPD, MD and ND, respectively. After controlling for genetic influences on CD, the partial genetic correlation between MD and ND was no longer statistically significant. Nonshared environmental contributions to the comorbidity among these disorders were not significant. This study not only demonstrates that the comorbidity between ND and MD is influenced by common genetic risk factors, but also further suggests that the common genetic risk factors overlapped with those for antisocial traits such as CD and ASPD in men.

Nicotine dependence is associated with depression and childhood trauma in smokers with schizophrenia. Results from the Face-SZ dataset

2017 ◽  
Vol 41 (S1) ◽  
pp. s831-s831
Author(s):  
R. Rey ◽  
T. D’amato ◽  
P.M. Llorca ◽  
G. Fond
Keyword(s):  
Smoking Cessation ◽  
Major Depression ◽  
Nicotine Dependence ◽  
Childhood Trauma ◽  
Male Gender ◽  
Community Dwelling ◽  
Psychotic Symptoms ◽  
Childhood Trauma Questionnaire ◽  
Personalized Care ◽  
Questionnaire Score

IntroductionIn a perspective of personalized care for smoking cessation, a better clinical characterization of smokers with schizophrenia (SZ) is needed. The objective of this study was to determine the clinical characteristics of SZ smokers with severe nicotine (NIC) dependence.MethodsTwo hundred and forty stabilized community-dwelling SZ smokers (mean age = 31.9 years, 80.4% male gender) were consecutively included in the network of the FondaMental Expert Centers for schizophrenia and assessed with validated scales. Severe NIC dependence was defined by a Fagerstrom questionnaire score ≥7. Major depression was defined by a Calgary score ≥6. Childhood trauma was self-reported by the Childhood Trauma Questionnaire score (CTQ). Ongoing psychotropic treatment was recorded.ResultsSevere NIC dependence was identified in 83 subjects (34.6%), major depression in 60 (26.3%). 44 (22.3%) subjects were treated by antidepressants. In a multivariate model, severe NIC dependence remained associated with major depression (OR = 3.155, P = 0.006), male gender (OR = 4.479, P = 0.009) and more slightly with childhood trauma (OR = 1.032, P = 0.044), independently of socio-demographic characteristics, psychotic symptoms severity, psychotropic treatments and alcohol disorder.ConclusionNIC dependence was independently and strongly associated with respectively major depression and male gender in schizophrenia, and only slightly with history of childhood trauma. Based on these results, the care of both nicotine dependence and depression should be evaluated for an effective smoking cessation intervention in schizophrenia. Bupropion, an antidepressant that has been found as the potential most effective strategy for tobacco cessation in schizophrenia to date, may be particularly relevant in male SZ smokers with comorbid major depression.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Self-efficacy to refrain from smoking predicted by major depression and nicotine dependence

2004 ◽  
Vol 29 (5) ◽  
pp. 857-866 ◽  
Author(s):  
U John ◽  
C Meyer ◽  
H.-J Rumpf ◽  
U Hapke
Keyword(s):  
Major Depression ◽  
Nicotine Dependence ◽  
Self Efficacy
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