scholarly journals On the biomechanical role of glycosaminoglycans in the aortic heart valve leaflet

2013 ◽  
Vol 9 (1) ◽  
pp. 4653-4660 ◽  
Author(s):  
Chad E. Eckert ◽  
Rong Fan ◽  
Brandon Mikulis ◽  
Mathew Barron ◽  
Christopher A. Carruthers ◽  
...  
Keyword(s):  
Heart Valve ◽  
Valve Leaflet ◽  
Aortic Heart Valve

The Role of Collagen Cross-Links in Biomechanical Behavior of Human Aortic Heart Valve Leaflets—Relevance for Tissue Engineering

2007 ◽  
Vol 13 (7) ◽  
pp. 1501-1511 ◽  
Author(s):  
Angelique Balguid ◽  
Mirjam P. Rubbens ◽  
Anita Mol ◽  
Ruud A. Bank ◽  
Ad J.J.C. Bogers ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Heart Valve ◽  
Aortic Heart Valve ◽  
Biomechanical Behavior ◽  
Cross Links

FEA of displacements and stresses of aortic heart valve leaflets during the opening phase

2019 ◽  
Vol 1-2 (92) ◽  
pp. 29-35
Author(s):  
O. Bialas ◽  
J. Żmudzki
Keyword(s):  
Aortic Valve ◽  
Heart Valve ◽  
Poisson Ratio ◽  
Elastic Behaviour ◽  
Valve Leaflet ◽  
Element Analysis ◽  
Linear Elastic ◽  
Material Thickness ◽  
Aortic Heart Valve ◽  
Opening Phase

Purpose: Modelling of biomechanical behaviour of heart valve materials aids improvement of biofunctional feature. The aim of the work was assessment of influence of material thickness of leaflets of artificial aortic valve on displacements and stresses during opening phase using finite element analysis (FEA). Design/methodology/approach: The model of aortic valve was developed on the basis of average anatomical valve shapes and dimensions. Nonlinear dynamic large displacements analysis with assumption of isotropic linear elastic material behaviour was used in simulation (Solidworks). The modulus of elasticity of 5.0 MPa was assumed and Poisson ratio set to 0.45. The rigidly supported leaflets was loaded by pressure increasing in the range 0-55 mmHg in time 0.1 s. Leaflets with material thickness 0.13 and 0.15 and 0.17 mm were analysed. The thickness was simulated with shell finite elements. Findings: The highest stresses were observed in the areas of fixation of the leaflets near the scaffold and were lower than dangerous value of fatigue of polyurethanes. Increasing the thickness of valve leaflet material in the range of 40 micrometres resulted in reduction of the valve outlet by almost 10 percent. Research limitations/implications: The FEA was limited to the isotropic linear-elastic behaviour of the material albeit can be used to assess leaflet deformation during dynamic load. Practical implications: Leaflets design may be start from efficient FEA which helps estimation of material impact on stress and fold formation which can affect local blood flow. Originality/value: Aortic heart valve leaflet material can be initially tested in dynamic conditions during opening phase with using FEA.

scholarly journals Time-dependent biaxial mechanical behavior of the aortic heart valve leaflet

2007 ◽  
Vol 40 (14) ◽  
pp. 3169-3177 ◽  
Author(s):  
John A. Stella ◽  
Jun Liao ◽  
Michael S. Sacks
Keyword(s):  
Mechanical Behavior ◽  
Heart Valve ◽  
Time Dependent ◽  
Valve Leaflet ◽  
Aortic Heart Valve

scholarly journals The concept of automated functional design of heart valve prostheses

2021 ◽  
Vol 10 (2) ◽  
pp. 63-67
Author(s):  
P. S. Onishchenko ◽  
K. Yu. Klyshnikov ◽  
M. A. Rezvova ◽  
E. A. Ovcharenko
Keyword(s):  
Numerical Modeling ◽  
Heart Valve ◽  
Von Mises Stress ◽  
Radius Of Curvature ◽  
Valve Leaflet ◽  
Functional Design ◽  
Aortic Heart Valve ◽  
Valve Prostheses ◽  
Von Mises ◽  
Matlab Programming

Aim. To develop an algorithm for the automated functional design of the heart valve leaflet apparatus.Methods. The geometry of the aortic valve leaflet was designed in the Matlab programming environment (MathWorks, Massachusetts, USA). Numerical modeling of the opening process was performed using Abaqus/CAE (Dassault Systemes, France).Results. We developed an algorithm, with the help of which a set of models of the leaflet apparatus was designed. 8 models were subjected to numerical modeling of the stress-strain state. The locking pressure simulation has shown that the smallest von Mises stress value was recorded for a sample with a larger surface area of the leaflet belly and it equals 0.422 MPa. The results obtained show that the value of the radius of curvature significantly affects the behavior of the entire valve, which leads to the conclusion that it is necessary to carefully select the design of the valve apparatus for its correct functioning.Conclusion. The study provides the primary confirmation that the concept of the algorithm is efficient for the automated functional design of the aortic heart valve leaflet apparatus. 

scholarly journals Interlayer micromechanics of the aortic heart valve leaflet

2013 ◽  
Vol 13 (4) ◽  
pp. 813-826 ◽  
Author(s):  
Rachel M. Buchanan ◽  
Michael S. Sacks
Keyword(s):  
Heart Valve ◽  
Valve Leaflet ◽  
Aortic Heart Valve
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