Resorbable composites with bioresorbable glass fibers for load-bearing applications. In vitro degradation and degradation mechanism

2013 ◽  
Vol 9 (1) ◽  
pp. 4868-4877 ◽  
Author(s):  
Timo J. Lehtonen ◽  
Jukka U. Tuominen ◽  
Elina Hiekkanen
Keyword(s):  
Degradation Mechanism ◽  
Glass Fibers ◽  
In Vitro Degradation ◽  
Load Bearing

Tensile properties and in vitro degradation of P(TMC-co-LLA) elastomers

2015 ◽  
Vol 3 (21) ◽  
pp. 4406-4416 ◽  
Author(s):  
Jorja Cork ◽  
Andrew K. Whittaker ◽  
Justin J. Cooper-White ◽  
Lisbeth Grøndahl
Keyword(s):  
Tensile Properties ◽  
Degradation Mechanism ◽  
In Vitro Degradation

The degradation mechanism of P(TMC-co-LLA) films was dependent on the LLA content and found to transition from heterogeneous to homogeneous bulk degradation.

scholarly journals Polylactide Composite Pins Reinforced with Bioresorbable Continuous Glass Fibers Demonstrating Bone-like Apatite Formation and Spiral Delamination Degradation

Polymers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 812
Author(s):  
Xiao-Yan Cao ◽  
Na Tian ◽  
Xiang Dong ◽  
Cheng-Kung Cheng
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Glass Fibers ◽  
Atomic Ratio ◽  
Apatite Formation ◽  
Degradation Behavior ◽  
Continuous Glass ◽  
Load Bearing ◽  
Sodium Magnesium

The emergence of polylactide composites reinforced with bioresorbable silicate glass fibers has allowed for the long-term success of biodegradable polymers in load-bearing orthopedic applications. However, few studies have reported on the degradation behavior and bioactivity of such biocomposites. The aim of this work was to investigate the degradation behavior and in vitro bioactivity of a novel biocomposite pin composed of bioresorbable continuous glass fibers and poly-L-D-lactide in simulated body fluid for 78 weeks. As the materials degraded, periodic spiral delamination formed microtubes and funnel-shaped structures in the biocomposite pins. It was speculated that the direction of degradation, from both ends towards the middle of the fibers and from the surface through to the bulk of the polymer matrix, could facilitate bone healing. Following immersion in simulated body fluid, a bone-like apatite layer formed on the biocomposite pins which had a similar composition and structure to natural bone. The sheet- and needle-like apatite nanostructure was doped with sodium, magnesium, and carbonate ions, which acted to lower the Ca/P atomic ratio to less than the stoichiometric apatite and presented a calcium-deficient apatite with low crystallinity. These findings demonstrated the bioactivity of the new biocomposite pins in vitro and their excellent potential for load-bearing applications.

In Vitro Degradation Of beta-Amyloid[25-35] Peptide

2001 ◽  
Vol 8 (6) ◽  
pp. 423-428 ◽  
Author(s):  
Krisztina Jost ◽  
Jozsef Varga ◽  
Botond Pence ◽  
Marta Zarandi
Keyword(s):  
Beta Amyloid ◽  
In Vitro Degradation

scholarly journals In Vitro Degradation of Absorbable Zinc Alloys in Artificial Urine

Materials ◽  
2019 ◽  
Vol 12 (2) ◽  
pp. 295 ◽  
Author(s):  
Sébastien Champagne ◽  
Ehsan Mostaed ◽  
Fariba Safizadeh ◽  
Edward Ghali ◽  
Maurizio Vedani ◽  
...  
Keyword(s):  
Surface Characterization ◽  
Urinary Tract Obstruction ◽  
Calcium Content ◽  
Corrosion Layer ◽  
Uniform Corrosion ◽  
In Vitro Degradation ◽  
Pure Zinc ◽  
Zinc Alloys ◽  
Artificial Urine

Absorbable metals have potential for making in-demand rigid temporary stents for the treatment of urinary tract obstruction, where polymers have reached their limits. In this work, in vitro degradation behavior of absorbable zinc alloys in artificial urine was studied using electrochemical methods and advanced surface characterization techniques with a comparison to a magnesium alloy. The results showed that pure zinc and its alloys (Zn–0.5Mg, Zn–1Mg, Zn–0.5Al) exhibited slower corrosion than pure magnesium and an Mg–2Zn–1Mn alloy. The corrosion layer was composed mostly of hydroxide, carbonate, and phosphate, without calcium content for the zinc group. Among all tested metals, the Zn–0.5Al alloy exhibited a uniform corrosion layer with low affinity with the ions in artificial urine.

Effects of Mn-doping on the structure and in vitro degradation of β-tricalcium phosphate

2021 ◽  
Author(s):  
Junjian Che ◽  
Hubiao Wang ◽  
Yunhai Ma ◽  
Feipeng Cao ◽  
Guoqin Liu ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
In Vitro Degradation ◽  
Mn Doping

In vitro degradation and drug release from polymer blends based on poly(dl-lactide), poly(l-lactide-glycolide) and poly(ε-caprolactone)

2009 ◽  
Vol 45 (5) ◽  
pp. 1284-1292 ◽  
Author(s):  
Paul F. McDonald ◽  
John G. Lyons ◽  
Luke M. Geever ◽  
Clement L. Higginbotham
Keyword(s):  
Drug Release ◽  
Polymer Blends ◽  
In Vitro Degradation

Covalent Grafting of Poly(l-lactide) to Tune the In Vitro Degradation Rate

2007 ◽  
Vol 8 (8) ◽  
pp. 2492-2496 ◽  
Author(s):  
Martina Källrot ◽  
Ulrica Edlund ◽  
Ann-Christine Albertsson
Keyword(s):  
Degradation Rate ◽  
In Vitro Degradation ◽  
Covalent Grafting
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