A new mitochondria-targeting fluorescent probe for ratiometric detection of H2O2 in live cells

2020 ◽  
Vol 1097 ◽  
pp. 230-237 ◽  
Author(s):  
Chengcheng Wang ◽  
Yang Wang ◽  
Guanyang Wang ◽  
Chusen Huang ◽  
Nengqin Jia
Keyword(s):  
Fluorescent Probe ◽  
Live Cells ◽  
Ratiometric Detection ◽  
Mitochondria Targeting

Ratiometric detection and imaging of hydrogen sulfide in mitochondria based on a cyanine/naphthalimide hybrid fluorescent probe

The Analyst ◽  
2020 ◽  
Vol 145 (20) ◽  
pp. 6549-6555
Author(s):  
Jing Liu ◽  
Xiangjun Liu ◽  
Shanshan Lu ◽  
Lingling Zhang ◽  
Le Feng ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Ratiometric Detection ◽  
Mitochondria Targeting

A novel fluorescent probe (L1) for ratiometric detection and imaging of H2S in mitochondria was developed by combining a H2S-sensitive naphthalimide fluorophore and a mitochondria targeting cyanine fluorophore.

Mitochondria-targeting NIR fluorescent probe for rapid, highly sensitive and selective visualization of nitroxyl in live cells, tissues and mice

2019 ◽  
Vol 63 (2) ◽  
pp. 282-289 ◽  
Author(s):  
Jianguo Wang ◽  
Wenping Zhu ◽  
Chunbin Li ◽  
Pengfei Zhang ◽  
Guoyu Jiang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Live Cells ◽  
Highly Sensitive ◽  
Mitochondria Targeting

scholarly journals A Fast-Response Red Shifted Fluorescent Probe for Detection of H2S in Living Cells

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 437 ◽  
Author(s):  
Ismail Ismail ◽  
Zhuoyue Chen ◽  
Xiuru Ji ◽  
Lu Sun ◽  
Long Yi ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Redox Homeostasis ◽  
Fast Response ◽  
Living Cells ◽  
Live Cells ◽  
Minimal Damage ◽  
Auto Fluorescence ◽  
Mitochondria Targeting

Near-infrared (NIR) fluorescent probes are attractive tools for bioimaging applications because of their low auto-fluorescence interference, minimal damage to living samples, and deep tissue penetration. H2S is a gaseous signaling molecule that is involved in redox homeostasis and numerous biological processes in vivo. To this end, we have developed a new red shifted fluorescent probe 1 to detect physiological H2S in live cells. The probe 1 is based on a rhodamine derivative as the red shifted fluorophore and the thiolysis of 7-nitro 1,2,3-benzoxadiazole (NBD) amine as the H2S receptor. The probe 1 displays fast fluorescent enhancement at 660 nm (about 10-fold turn-ons, k2 = 29.8 M−1s−1) after reacting with H2S in buffer (pH 7.4), and the fluorescence quantum yield of the activated red shifted product can reach 0.29. The probe 1 also exhibits high selectivity and sensitivity towards H2S. Moreover, 1 is cell-membrane-permeable and mitochondria-targeting, and can be used for imaging of endogenous H2S in living cells. We believe that this red shifted fluorescent probe can be a useful tool for studies of H2S biology.

scholarly journals An ultrasensitive near-infrared ratiometric fluorescent probe for imaging mitochondrial polarity in live cells and in vivo

2016 ◽  
Vol 7 (2) ◽  
pp. 1588-1593 ◽  
Author(s):  
Haibin Xiao ◽  
Ping Li ◽  
Wei Zhang ◽  
Bo Tang
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Live Cells ◽  
Mitochondria Targeting ◽  
Ratiometric Fluorescent Probe

We describe a new mitochondria-targeting fluorescent probeMCY-BF2that is singularly sensitive and specifically responsive to mitochondrial polarity.

A colorimetric and ratiometric fluorescent probe for cyanide sensing in aqueous media and live cells

2019 ◽  
Vol 7 (30) ◽  
pp. 4620-4629 ◽  
Author(s):  
Lingjie Hou ◽  
Fan Li ◽  
Jinchang Guo ◽  
Xiaoying Zhang ◽  
Xiangyu Kong ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Aqueous Media ◽  
Live Cells ◽  
Cyanide Sensing ◽  
Mitochondria Targeting ◽  
Ratiometric Fluorescent Probe

A mitochondria-targeting ratiometric fluorescent probe for cyanide was reported.

Turn-on fluorescent probe for dopamine detection in solutions and live cells based on in situ formation of aminosilane-functionalized carbon dots

2021 ◽  
Vol 1157 ◽  
pp. 338394
Author(s):  
Xiao-Yue Tang ◽  
Yi-Ming Liu ◽  
Xiao-Lin Bai ◽  
Hao Yuan ◽  
Yi-Kao Hu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Carbon Dots ◽  
Live Cells ◽  
Turn On ◽  
Dopamine Detection ◽  
In Situ Formation

A smart mitochondria-targeting TP-NIR fluorescent probe for selective and sensitive sensing H2S in living cells and mice

2021 ◽  
Author(s):  
Qiaomei Yang ◽  
Liyi Zhou ◽  
Longpeng Peng ◽  
Gangqiang Yuan ◽  
Haiyuan Ding ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Signal Molecules ◽  
Two Photon ◽  
Mitochondria Targeting

Hydrogen sulfide (H2S) is one of the important gaseous signal molecules and plays key roles in various biologically crucial processes. In this work, we report a novel two-photon near-infrared (TP-NIR)...

scholarly journals A rapid “on–off–on” mitochondria-targeted phosphorescent probe for selective and consecutive detection of Cu2+ and cysteine in live cells and zebrafish

RSC Advances ◽  
2021 ◽  
Vol 11 (13) ◽  
pp. 7610-7620 ◽  
Author(s):  
Peipei Deng ◽  
Yongyan Pei ◽  
Mengling Liu ◽  
Wenzhu Song ◽  
Mengru Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Living Cells ◽  
Live Cells ◽  
Mitochondria Targeting

An iridium(iii) complex-based mitochondria targeting phosphorescent probe for selectively detecting Cu2+ and Cys in aqueous solution, living cells and zebrafish has been developed.

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