Antipsychotic drug poisoning monitoring of clozapine in urine by using coffee ring effect based surface-enhanced Raman spectroscopy

2018 ◽  
Vol 1014 ◽  
pp. 64-70 ◽  
Author(s):  
Qingxia Zhu ◽  
Xiaoyan Yu ◽  
Zebing Wu ◽  
Feng Lu ◽  
Yongfang Yuan
Keyword(s):  
Raman Spectroscopy ◽  
Antipsychotic Drug ◽  
Surface Enhanced Raman Spectroscopy ◽  
Drug Poisoning ◽  
Coffee Ring ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Coffee Ring Effect ◽  
Ring Effect

Surface-enhanced Raman spectroscopy using a coffee-ring-type three-dimensional silver nanostructure

RSC Advances ◽  
2015 ◽  
Vol 5 (2) ◽  
pp. 1378-1384 ◽  
Author(s):  
R. Hara ◽  
T. Fukuoka ◽  
R. Takahashi ◽  
Y. Utsumi ◽  
A. Yamaguchi
Keyword(s):  
Raman Spectroscopy ◽  
Three Dimensional ◽  
Surface Enhanced Raman Spectroscopy ◽  
Ring Type ◽  
Silver Nanostructure ◽  
Coffee Ring ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

We demonstrated surface-enhanced Raman spectroscopy using a coffee-ring-type three-dimensional silver nanostructure (Ag3D).

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

Sign in / Sign up

Export Citation Format

Share Document