A comparison of electrochemically pre-treated and spark-platinized carbon fiber microelectrode. Measurement of 8-oxo-7,8-dihydro-2′-deoxyguanosine in human urine and plasma

2016 ◽  
Vol 935 ◽  
pp. 82-89 ◽  
Author(s):  
Z. Bartosova ◽  
D. Riman ◽  
V. Halouzka ◽  
J. Vostalova ◽  
V. Simanek ◽  
...  
Keyword(s):  
Carbon Fiber ◽  
Human Urine ◽  
Carbon Fiber Microelectrode ◽  
Platinized Carbon

scholarly journals Laser Sharpening of Carbon Fiber Microelectrode Arrays for Brain Recording

2020 ◽  
Vol 8 (4) ◽  
Author(s):  
Tianshu Dong ◽  
Lei Chen ◽  
Albert Shih
Keyword(s):  
Carbon Fiber ◽  
Electrical Discharge Machining ◽  
Electrochemical Impedance ◽  
Microelectrode Arrays ◽  
Small Diameter ◽  
Input Voltage ◽  
Bath Surface ◽  
Insertion Force ◽  
Carbon Fiber Microelectrode ◽  
The Brain

Abstract Microwire microelectrode arrays (MEAs) are implanted in the brain for recording neuron activities to study the brain function. Among various microwire materials, carbon fiber stands out due to its small diameter (5–10 μm), relatively high Young's modulus, and low electrical resistance. Microwire tips in MEAs are often sharpened to reduce the insertion force and prevent the thin microwires from buckling. Currently, carbon fiber MEAs are sharpened by either torch burning, which limits the positions of wire tips to a water bath surface plane, or electrical discharge machining, which is difficult to implement to the nonelectrically conductive carbon fiber with parylene-C insulation. A laser-based carbon fiber sharpening method proposed in this study enables the fabrication of carbon fiber MEAs with sharp tips and custom lengths. Experiments were conducted to study effects of laser input voltage and transverse speed on carbon fiber tip geometry. Results of the tip sharpness and stripped length of the insulation as well as the electrochemical impedance spectroscopy measurement at 1 kHz were evaluated and analyzed. The laser input voltage and traverse speed have demonstrated to be critical for the sharp tip, short stripped length, and low electrical impedance of the carbon fiber electrode for brain recording MEAs. A carbon fiber MEA with custom electrode lengths was fabricated to validate the laser-based approach.

scholarly journals Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin

The Analyst ◽  
2016 ◽  
Vol 141 (18) ◽  
pp. 5256-5260 ◽  
Author(s):  
Elefterios Trikantzopoulos ◽  
Cheng Yang ◽  
Mallikarjunarao Ganesana ◽  
Ying Wang ◽  
B. Jill Venton
Keyword(s):  
Carbon Fiber ◽  
Carbon Fiber Microelectrode ◽  
Batch Fabrication ◽  
3D Printed

Laser Sharpening of Carbon Fiber Microelectrode Arrays for Brain Recording

2020 ◽  
Author(s):  
Tianshu Dong ◽  
Lei Chen ◽  
Albert Shih
Keyword(s):  
Carbon Fiber ◽  
Output Power ◽  
Electrical Discharge Machining ◽  
Microelectrode Arrays ◽  
Insertion Force ◽  
Speed Test ◽  
Carbon Fiber Microelectrode ◽  
Array Pattern ◽  
The Brain ◽  
Moving Speed

Abstract Microwire microelectrode arrays (MEAs) are implanted in the brain for recording neuron activities to study the brain functioning mechanism. Among various microwire materials that had been applied, carbon fiber is outstanding due to its small footprint (6–7 μm), relatively high Young’s modulus, and low electrical resistance. Tips of microwire in MEAs are often sharpened to reduce insertion force. Currently, carbon fiber MEAs are sharpened with either torch burning, which can only give a uniform length of wires in an array, or electrical discharge machining (EDM), which requires circuit connection with each single carbon fiber. The sharp tip results from intense burning induced by a flame or spark, leading to poor repeatability and controllability of the sharp tip geometry. In this paper, a laser-based, non-contact carbon fiber sharpening method is proposed, which enables controllable and repeatable production of carbon fiber MEAs of custom electrode lengths, insulation stripping lengths, and sharpened tips. Path of laser movement is designed according to desired array pattern. Variation in tip geometry can be accomplished by changing laser output power and moving speed. Test with different laser parameters (output power and moving speed) were conducted. Tip sharpening results were evaluated and analyzed in terms of tip geometry and insulation stripping length. Results showed that to achieve the desired MEA with sharper tip and shorter insulation stripping length, a higher laser power with faster moving speed is preferred.

Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording

10.3791/63099 ◽  
2021 ◽  
Author(s):  
Julianna M. Richie ◽  
Paras R. Patel ◽  
Elissa J. Welle ◽  
Tianshu Dong ◽  
Lei Chen ◽  
...  
Keyword(s):  
Carbon Fiber ◽  
Open Source ◽  
Microelectrode Array ◽  
Carbon Fiber Microelectrode

In Vivo Monitoring of Oxygen in Rat Brain by Carbon Fiber Microelectrode Modified with Antifouling Nanoporous Membrane

2019 ◽  
Vol 91 (5) ◽  
pp. 3645-3651 ◽  
Author(s):  
Lin Zhou ◽  
Hanfeng Hou ◽  
Huan Wei ◽  
Lina Yao ◽  
Lei Sun ◽  
...  
Keyword(s):  
Carbon Fiber ◽  
Rat Brain ◽  
Nanoporous Membrane ◽  
In Vivo Monitoring ◽  
Carbon Fiber Microelectrode
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