Analytical performance of molecular beacons on surface immobilized gold nanoparticles of varying size and density

2013 ◽  
Vol 803 ◽  
pp. 113-122 ◽  
Author(s):  
Uvaraj Uddayasankar ◽  
Ulrich J. Krull
Keyword(s):  
Gold Nanoparticles ◽  
Molecular Beacons ◽  
Analytical Performance

Gold nanoparticles based molecular beacons for in vitro and in vivo detection of the matriptase expression on tumor

2013 ◽  
Vol 49 ◽  
pp. 216-221 ◽  
Author(s):  
Dawei Deng ◽  
Dongyin Zhang ◽  
Yang Li ◽  
Samuel Achilefu ◽  
Yueqing Gu
Keyword(s):  
Gold Nanoparticles ◽  
Molecular Beacons ◽  
In Vivo Detection

A tumour mRNA-triggered nanocarrier for multimodal cancer cell imaging and therapy

2014 ◽  
Vol 50 (56) ◽  
pp. 7473-7476 ◽  
Author(s):  
Na Li ◽  
Huijun Yang ◽  
Wei Pan ◽  
Wei Diao ◽  
Bo Tang
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cell ◽  
Cell Imaging ◽  
Molecular Beacons ◽  
Cancer Cell Imaging ◽  
Tumor Mrna

A tumor mRNA-triggered nanocarrier was established for multimodal cancer cell imaging and therapy based on the gold nanoparticles functionalized with molecular beacons.

scholarly journals Comparison of Single- and Mixed-Sized Gold Nanoparticles on Lateral Flow Assay for Albumin Detection

Biosensors ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 209
Author(s):  
Sasima Chotithammakul ◽  
Michael B. Cortie ◽  
Dakrong Pissuwan
Keyword(s):  
Chronic Kidney Disease ◽  
Gold Nanoparticles ◽  
Test Line ◽  
Lateral Flow ◽  
Lateral Flow Assay ◽  
Analytical Performance ◽  
Detection Mechanism ◽  
Multiple Factors ◽  
20 Nm ◽  
Target Analyte

The sensitivity and reproducibility of the lateral flow assay can be influenced by multiple factors, such as the size of gold nanoparticles (GNPs) employed. Here, we evaluated the analytical performance of single-sized and mixed-sized GNPs using a simple lateral flow assay (LFA) platform. This platform was used as a model assay to diagnose albumin levels and demonstrate the analytical performance of single-sized and mixed-sized GNPs in LFA tests. Two sizes of GNPs@anti-bovine serum albumin (BSA) conjugate proteins were mixed at different ratios. The unique optical properties of the GNPs induced a distinguishing color-shedding effect on the single- and mixed-sized GNPs@anti-BSA conjugates interacting with the target analyte BSA spotted on the test line. The use of mixed-sized GNPs@anti-BSA conjugates enhanced signal relative to the 20 nm GNPs, and provided superior stability compared with solely employing the large GNPs (50 nm). The proposed platform in this study could provide an efficient BSA detection mechanism that can be utilized as a model biomarker for confronting chronic kidney disease.

Electrochemical sensors of octylphenol based on molecularly imprinted poly(3,4-ethylenedioxythiophene) and poly(3,4-ethylenedioxythiophene–gold nanoparticles)

RSC Advances ◽  
2015 ◽  
Vol 5 (71) ◽  
pp. 57671-57677 ◽  
Author(s):  
Yanhui Pan ◽  
Faqiong Zhao ◽  
Baizhao Zeng
Keyword(s):  
Gold Nanoparticles ◽  
Electrochemical Sensors ◽  
Graphene Nanoribbons ◽  
Analytical Performance ◽  
Molecularly Imprinted ◽  
Octyl Phenol

Two molecularly imprinted electrochemical sensors are fabricated by using EDOT and EDOT–AuNPs as monomers, respectively. The sensors show good analytical performance for OP sensing. Note: graphene nanoribbons (GNRs), 3,4-ethylenedioxythiophene (EDOT), 4-tert-octyl-phenol (OP).

Performance comparison of single and mixed-sized gold nanoparticles on straightforward lateral flow assay for albumin detection

2020 ◽  
Author(s):  
Sasima Chotithammakul ◽  
Dakrong Pissuwan
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Test Line ◽  
Testing Procedure ◽  
Performance Comparison ◽  
Lateral Flow ◽  
Lateral Flow Assay ◽  
Analytical Performance ◽  
Detection Mechanism ◽  
Multiple Factors

The sensitivity of the lateral flow assay can be influenced by multiple factors, such as the size of gold nanoparticles (GNPs) employed, which affect the sensitivity and reproducibility of the assay testing procedure. Here, we evaluated the analytical performance of single-sized and mixed-sized GNPs using a simple lateral flow assay (LFA) platform. This platform was used as a model assay to diagnose albumin levels and demonstrate the analytical performance of single-sized and mixed-sized GNPs in LFA tests. Two sizes of GNPs@anti-bovine serum albumin (BSA) conjugate proteins were mixed at different ratios. The unique optical properties of the GNPs induced a distinguishing color-shedding effect on the single and mixed-sized GNPs@anti-BSA conjugates interacting with the target analyte BSA spotted on the test line. The use of mixed-sized GNPs@anti-BSA conjugates enhanced signal amplification, and provided superior stability compared with solely employing the large GNPs (50 nm). The proposed platform in this study could provide an efficient BSA detection mechanism that can be utilized as a biomarker for confronting chronic kidney disease.

Photo-tethered molecular beacons for superior light-induction

2021 ◽  
Author(s):  
Robin Klimek ◽  
Mantian Wang ◽  
Vivien R. McKenney ◽  
Erin M. Schuman ◽  
Alexander Heckel
Keyword(s):  
Molecular Beacons ◽  
Light Induction ◽  
In Cells

Photolabile circularization of molecular beacons via backbone phosphates leads to superior probes to study spatiotemporal aspects of RNA in cells.

EpCam-specific Gold Nanoparticles for Detection, Live-imaging and Rapid Enrichment of Adult Human Liver Progenitor Cells

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
N Fekete-Drimusz ◽  
J de la Roche ◽  
F Vondran ◽  
CL Sajti ◽  
MP Manns ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Progenitor Cells ◽  
Human Liver ◽  
Live Imaging ◽  
Adult Human
Sign in / Sign up

Export Citation Format

Share Document