A label-free electrochemical biosensor based on a DNA aptamer against codeine

2013 ◽  
Vol 787 ◽  
pp. 203-210 ◽  
Author(s):  
Liangliang Huang ◽  
Xiaojuan Yang ◽  
Cui Qi ◽  
Xiaofang Niu ◽  
Chunling Zhao ◽  
...  
Keyword(s):  
Electrochemical Biosensor ◽  
Dna Aptamer ◽  
Label Free

A simple label-free electrochemical aptasensor for dopamine detection

RSC Advances ◽  
2014 ◽  
Vol 4 (94) ◽  
pp. 52250-52255 ◽  
Author(s):  
Jiawan Zhou ◽  
Wenyang Wang ◽  
Peng Yu ◽  
Erhu Xiong ◽  
Xiaohua Zhang ◽  
...  
Keyword(s):  
Electrochemical Biosensor ◽  
Dna Aptamer ◽  
Selective Detection ◽  
Label Free ◽  
Electrochemical Aptasensor ◽  
Dopamine Detection

A simple and label-free electrochemical biosensor based on a dopamine DNA aptamer was developed for the sensitive and selective detection of dopamine.

scholarly journals DNA Aptamer Functionalized Hydrogels for Interferometric Fiber-Optic Based Continuous Monitoring of Potassium Ions

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 266
Author(s):  
Nataša Žuržul ◽  
Bjørn Torger Stokke
Keyword(s):  
Conformational Transition ◽  
Polymer Network ◽  
Potassium Ion ◽  
Ion Concentration ◽  
Dna Aptamer ◽  
Blood Levels ◽  
Label Free ◽  
Practical Applications ◽  
Hydrogel Matrix ◽  
K Concentration

In the present paper, we describe a potassium sensor based on DNA-aptamer functionalized hydrogel, that is capable of continuous label-free potassium ion (K+) monitoring with potential for in situ application. A hydrogel attached to the end of an optical fiber is designed with di-oligonucleotides grafted to the polymer network that may serve as network junctions in addition to the covalent crosslinks. Specific affinity toward K+ is based on exploiting a particular aptamer that exhibits conformational transition from single-stranded DNA to G-quadruplex formed by the di-oligonucleotide in the presence of K+. Integration of this aptamer into the hydrogel transforms the K+ specific conformational transition to a K+ concentration dependent deswelling of the hydrogel. High-resolution interferometry monitors changes in extent of swelling at 1 Hz and 2 nm resolution for the hydrogel matrix of 50 µm. The developed hydrogel-based biosensor displayed high selectivity for K+ ions in the concentration range up to 10 mM, in the presence of physiological concentrations of Na+. Additionally, the concentration dependent and selective K+ detection demonstrated in the artificial blood buffer environment, both at room and physiological temperatures, suggests substantial potential for practical applications such as monitoring of potassium ion concentration in blood levels in intensive care medicine.

A novel label free long non-coding RNA electrochemical biosensor based on green l-cysteine electrodeposition and Au–Rh hollow nanospheres as tags

RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 51990-51999 ◽  
Author(s):  
Fei Liu ◽  
Guiming Xiang ◽  
Liqun Zhang ◽  
Dongneng Jiang ◽  
Linlin Liu ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Single Wall Carbon Nanotubes ◽  
Complex Signal ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Hollow Nanospheres ◽  
Non Coding Rna ◽  
Long Non Coding Rna

lncRNA biosensor based on single-wall carbon nanotubes wrapped with Au–Rh hollow nanospheres (Au/Rh-HNP@SWCNT) complex signal amplification and an l-Cys Au nano-film provided ultrasensitive detection for the nuclear paraspeckle assembly transcript 1 (NEAT1).

Selection of a DNA Aptamer against Zearalenone and Docking Analysis for Highly Sensitive Rapid Visual Detection with Label-Free Aptasensor

2018 ◽  
Vol 66 (45) ◽  
pp. 12102-12110 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Taofeng Lu ◽  
Yue Wang ◽  
Chenxi Diao ◽  
Yan Zhou ◽  
...  
Keyword(s):  
Visual Detection ◽  
Dna Aptamer ◽  
Label Free ◽  
Docking Analysis ◽  
Highly Sensitive ◽  
Selection Of
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