Highly sensitive luminol electrochemiluminescence immunosensor based on ZnO nanoparticles and glucose oxidase decorated graphene for cancer biomarker detection

2012 ◽  
Vol 745 ◽  
pp. 137-142 ◽  
Author(s):  
Yinfeng Cheng ◽  
Ruo Yuan ◽  
Yaqin Chai ◽  
Huan Niu ◽  
Yaling Cao ◽  
...  
Keyword(s):  
Glucose Oxidase ◽  
Zno Nanoparticles ◽  
Cancer Biomarker ◽  
Biomarker Detection ◽  
Highly Sensitive

Cubic CeO2implanted reduced graphene oxide-based highly sensitive biosensor for non-invasive oral cancer biomarker detection

2018 ◽  
Vol 6 (19) ◽  
pp. 3000-3012 ◽  
Author(s):  
Namrata Pachauri ◽  
Kashyap Dave ◽  
Amit Dinda ◽  
Pratima R. Solanki
Keyword(s):  
Graphene Oxide ◽  
Oral Cancer ◽  
Reduced Graphene Oxide ◽  
Cerium Oxide ◽  
Cancer Biomarker ◽  
Electrochemical Technique ◽  
Biomarker Detection ◽  
Non Invasive ◽  
Reduced Graphene ◽  
Highly Sensitive

Herein, we report a cerium oxide nanocubes (ncCeO2)–reduced graphene oxide (RGO)-based nanocomposite for the detection of oral cancer biomarker, cytokeratin fragment-21-1 (Cyfra-21-1), using the electrochemical technique.

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

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