scholarly journals Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex

2012 ◽  
Vol 519 (2) ◽  
pp. 154-166 ◽  
Author(s):  
Michael F. Dunn
Keyword(s):  
Allosteric Regulation ◽  
Tryptophan Synthase ◽  
Substrate Channeling

Allosteric Regulation of Substrate Channeling in Tryptophan Synthase:  Modulation of thel-Serine Reaction in Stage I of the β-Reaction by α-Site Ligands†,‡

Biochemistry ◽  
2007 ◽  
Vol 46 (26) ◽  
pp. 7740-7753 ◽  
Author(s):  
Huu Ngo ◽  
Novelle Kimmich ◽  
Rodney Harris ◽  
Dimitri Niks ◽  
Lars Blumenstein ◽  
...  
Keyword(s):  
Allosteric Regulation ◽  
Stage I ◽  
Tryptophan Synthase ◽  
Substrate Channeling

βD305A Mutant of Tryptophan Synthase Shows Strongly Perturbed Allosteric Regulation and Substrate Specificity†

Biochemistry ◽  
2001 ◽  
Vol 40 (25) ◽  
pp. 7421-7432 ◽  
Author(s):  
Davide Ferrari ◽  
Li-Hong Yang ◽  
Edith W. Miles ◽  
Michael F. Dunn
Keyword(s):  
Substrate Specificity ◽  
Allosteric Regulation ◽  
Tryptophan Synthase

Allosteric Regulation of Tryptophan Synthase Channeling:  The Internal Aldimine Probed bytrans-3-Indole-3‘-acrylate Binding†

Biochemistry ◽  
2007 ◽  
Vol 46 (26) ◽  
pp. 7728-7739 ◽  
Author(s):  
Patricia Casino ◽  
Dimitri Niks ◽  
Huu Ngo ◽  
Peng Pan ◽  
Peter Brzovic ◽  
...  
Keyword(s):  
Allosteric Regulation ◽  
Tryptophan Synthase

Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex†,‡

Biochemistry ◽  
2007 ◽  
Vol 46 (26) ◽  
pp. 7713-7727 ◽  
Author(s):  
Huu Ngo ◽  
Rodney Harris ◽  
Novelle Kimmich ◽  
Patricia Casino ◽  
Dimitri Niks ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Tryptophan Synthase ◽  
Substrate Channeling

On the Role of αThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase

2002 ◽  
Vol 324 (4) ◽  
pp. 677-690 ◽  
Author(s):  
Victor Kulik ◽  
Michael Weyand ◽  
Ralf Seidel ◽  
Dimitri Niks ◽  
Demet Arac ◽  
...  
Keyword(s):  
Catalytic Mechanism ◽  
Allosteric Regulation ◽  
Tryptophan Synthase

scholarly journals Allostery and Substrate Channeling in the Tryptophan Synthase Bienzyme Complex: Evidence for Two Subunit Conformations and Four Quaternary States

Biochemistry ◽  
2013 ◽  
Vol 52 (37) ◽  
pp. 6396-6411 ◽  
Author(s):  
Dimitri Niks ◽  
Eduardo Hilario ◽  
Adam Dierkers ◽  
Huu Ngo ◽  
Dan Borchardt ◽  
...  
Keyword(s):  
Tryptophan Synthase ◽  
Substrate Channeling
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