Facile detection of microRNA based on phosphorescence resonance energy transfer and duplex-specific nuclease-assisted signal amplification

2017 ◽  
Vol 539 ◽  
pp. 127-133 ◽  
Author(s):  
Jia-jia Yang ◽  
Zhi-feng Zhang ◽  
Gui-qin Yan
2018 ◽  
Vol 54 (77) ◽  
pp. 10897-10900 ◽  
Author(s):  
Zhi-Bin Wen ◽  
Wen-Bin Liang ◽  
Ying Zhuo ◽  
Cheng-Yi Xiong ◽  
Ying-Ning Zheng ◽  
...  

Herein, an adenosine triphosphate (ATP)-fueled nucleic acid signal amplification strategy based on toehold-mediated strand displacement (TMSD) and fluorescence resonance energy transfer (FRET) was proposed for highly sensitive detection of microRNA-21.


2018 ◽  
Vol 54 (84) ◽  
pp. 11861-11864 ◽  
Author(s):  
Chen Zong ◽  
Jie Wu ◽  
Yang Zang ◽  
Huangxian Ju

A novel enzyme-free chemiluminescence system based on CdTe quantum dots along with a CL signal amplification strategy was designed for sensitive immunoassay.


The Analyst ◽  
2020 ◽  
Vol 145 (21) ◽  
pp. 6992-6999
Author(s):  
Bei Zhang ◽  
Lu Shi ◽  
Wei Liu ◽  
Baoxin Li ◽  
Yan Jin

A reliable, sensitive and immobilization-free method was developed for the detection of intracellular telomerase activity by combining double signal amplification with ratiometric FRET.


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